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51 results on '"Stratton, Michael R"'

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1. A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

2. Combined burden and functional impact tests for cancer driver discovery using DriverPower

3. Integrative pathway enrichment analysis of multivariate omics data

4. Pathway and network analysis of more than 2500 whole cancer genomes

5. Divergent mutational processes distinguish hypoxic and normoxic tumours

6. Genomic footprints of activated telomere maintenance mechanisms in cancer

7. Mutational processes molding the genomes of 21 breast cancers

8. The life history of 21 breast cancers

9. Recurrent histone mutations in T-cell acute lymphoblastic leukaemia

10. Short inverted repeats contribute to localized mutability in human somatic cells

11. RNA editing of human microRNAs

12. Timing, rates and spectra of human germline mutation

13. The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

14. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

15. A mutational signature in gastric cancer suggests therapeutic strategies

16. Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

17. Signatures of mutational processes in human cancer

18. International network of cancer genome projects

19. A small-cell lung cancer genome with complex signatures of tobacco exposure

20. Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

21. Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

22. Subclonal diversification of primary breast cancer revealed by multiregion sequencing

23. Somatic Evolution in Non-neoplastic IBD-Affected Colon

24. Somatic mutation landscapes at single-molecule resolution

25. DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

26. Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis

27. HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

28. Sex differences in oncogenic mutational processes

29. Landscape of somatic mutations in 560 breast cancer whole-genome sequences

30. The genome as a record of environmental exposure

31. Somatic mutant clones colonize the human esophagus with age

32. Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

33. Pan-cancer analysis of whole genomes

34. Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

35. Sex differences in oncogenic mutational processes

36. Population dynamics of normal human blood inferred from somatic mutations

37. Signatures of mutational processes in human cancer

38. Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

39. Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

40. A mutational signature in gastric cancer suggests therapeutic strategies

41. Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

42. Recurrent rearrangements of FOS and FOSB define osteoblastoma

43. A small-cell lung cancer genome with complex signatures of tobacco exposure

44. Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

45. Somatic mutation rates scale with lifespan across mammals

46. Convergent somatic mutations in metabolism genes in chronic liver disease

47. Mutational landscape of normal epithelial cells in Lynch Syndrome patients

48. Somatic mutation landscapes at single-molecule resolution

49. Somatic mutant clones colonize the human esophagus with age

50. Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

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