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32 results on '"Vachier, Isabelle"'

1. Empty outcome table

Author

Suehs, Carey, Bourdin, Arnaud, Nicolas, Audrey, Martinez, Aurelie, Molinari, Nicolas, and Vachier, Isabelle

Published
2022
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2. CLIPPCAIR

Author

Bommart, Sébastien, Suehs, Carey, Marty-Ané, Charles, Vachier, Isabelle, Charriot, Jeremy, Hrieche, Kheira, Solovei, Laurence, Hayot, Maurice, Gouzi, Fares, Serre, Isabelle, Molinari, Nicolas, and Bourdin, Arnaud

Subjects
Medicine and Health Sciences
Abstract

The primary objective of the CLIPPCAIR study is to construct and validate a new algorithm for predicting post-operative forced expiratory volume in 1 second (FEV1) values for lung resection candidates; this new model will be based on data derived from a thoracic CT scan with injection of contrast media. This registration includes information contained in the eCRF.

Published
2022
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4. CortiCORONA

Author

Boissin, Clement, Charriot, Jeremy, Bourdin, Arnaud, Vachier, Isabelle, Suehs, Carey, and Molinari, Nicolas

Subjects
body regions, viruses, fungi, Medicine and Health Sciences, skin and connective tissue diseases, respiratory tract diseases
Abstract

Determination of biomarkers to predict the response to treatment with dexamethasone for Sars-Cov(2 / COVID-19 pneumonia

Published
2022
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5. CLIPPCAIR

Author

Bommart, Sébastien, Suehs, Carey, Marty-Ané, Charles, Vachier, Isabelle, Charriot, Jeremy, Hrieche, Kheira, Solovei, Laurence, Hayot, Maurice, Gouzi, Fares, Serre, Isabelle, Molinari, Nicolas, and Bourdin, Arnaud

Subjects
Medicine and Health Sciences, lung resection, fev1, lung function, spirometry
Abstract

The primary objective of the CLIPPCAIR study is to construct and validate a new algorithm for predicting post-operative forced expiratory volume in 1 second (FEV1) values for lung resection candidates; this new model will be based on data derived from a thoracic CT scan with injection of contrast media.

Published
2022
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6. CortiCORONA

Author

Boissin, Clement, Charriot, Jeremy, Bourdin, Arnaud, Vachier, Isabelle, Suehs, Carey, and Molinari, Nicolas

Subjects
body regions, viruses, fungi, Medicine and Health Sciences, corticosteroid response, COVID-19, SARS-COV-2, skin and connective tissue diseases, respiratory tract diseases
Abstract

Determination of biomarkers to predict the response to treatment with dexamethasone for Sars-Cov(2 / COVID-19 pneumonia

Published
2022
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8. eo-Delphi

Author

Suehs, Carey, Vachier, Isabelle, Molinari, Nicolas, and Bourdin, Arnaud

Abstract

eo-Delphi aims to create consensus for a core set of outcomes for the eo-Drive protocol using a modified Delphi method.

Published
2022
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10. Protocol

Author

Suehs, Carey, Boissin, Clement, Charriot, Jeremy, Bourdin, Arnaud, Vachier, Isabelle, and Molinari, Nicolas

Published
2022
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12. Study documents

Author

Suehs, Carey, Boissin, Clement, Charriot, Jeremy, Bourdin, Arnaud, Vachier, Isabelle, and Molinari, Nicolas

Published
2022
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13. The eo-Delphi protocol

Author

Suehs, Carey, Molinari, Nicolas, Vachier, Isabelle, and Bourdin, Arnaud

Subjects
modified delphi process, COPD, eo-Delphi, eosinophils, protocol, delphi process, corticosteroids
Published
2022
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14. CortiCORONA

Author

Boissin, Clement, Charriot, Jeremy, Bourdin, Arnaud, Vachier, Isabelle, Suehs, Carey, and Molinari, Nicolas

Subjects
body regions, viruses, fungi, skin and connective tissue diseases, respiratory tract diseases
Abstract

Determination of biomarkers to predict the response to treatment with dexamethasone for Sars-Cov(2 / COVID-19 pneumonia

Published
2022
Full Text
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15. CortiCORONA

Author

Boissin, Clement, Charriot, Jeremy, Bourdin, Arnaud, Vachier, Isabelle, Suehs, Carey, and Molinari, Nicolas

Subjects
body regions, viruses, fungi, Medicine and Health Sciences, CORTICOSTEROIDS, COVID-19, skin and connective tissue diseases, respiratory tract diseases
Abstract

Determination of biomarkers to predict the response to treatment with dexamethasone for Sars-Cov(2 / COVID-19 pneumonia

Published
2022
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17. Protocol

Author

Suehs, Carey, Boissin, Clement, Charriot, Jeremy, Bourdin, Arnaud, Vachier, Isabelle, and Molinari, Nicolas

Published
2022
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19. COPD-CARhE

Author

Charriot, Jeremy, Suehs, Carey, Vachier, Isabelle, Gamez, Anne-Sophie, Jean, Romain, Berger, Patrick, Zysman, Maeva, Guilleminault, Laurent, Didier, Alain, Brouquières, Danielle, Guibert, Nicolas, Marchandise, Sandrine, Molinari, Nicolas, and Bourdin, Arnaud

Published
2022
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20. PROTOACCEPT2

Author

Barrionuevo, Christian, Vachier, Isabelle, Suehs, Carey, Molinari, Nicolas, and Bourdin, Arnaud

Published
2022
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22. eo-Drive

Author

Bourdin, Arnaud, Suehs, Carey, Vachier, Isabelle, Molinari, Nicolas, Chanez, Pascal, Roche, Nicolas, Burgel, Pierre-Régis, Chinet, Thierry, Demoule, Alexandre, Similowski, Thomas, Morelot, Capucine, Londner, Cecile, Chenivesse, Cecile, Le Rouzic, Olivier, Bautin, Nathalie, Perez, Thierry, Raherison, Chantal, Molimard, Mathieu, Berger, Patrick, Girodet, Pierre, Yali, Matthieu, Devouassoux, Gilles, Didier, Alain, Noel-Savina, Elise, Couturaud, Francis, DESLEE, Chabaud, François, Chaouat, Ari, Guillaumot, Anne, Zysman, Maeva, Devillier, Philippe, Kessler, Romain, Just, Nicolas, Gamez, Anne-Sophie, and Boyer, Laurent

Subjects
exacerbation, biomarker driven, COPD, eosinophilia, corticosteroids, hospitalization
Published
2022
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23. CLIPPCAIR

Author

Bommart, Sébastien, Suehs, Carey, Marty-Ané, Charles, Vachier, Isabelle, Charriot, Jeremy, Hrieche, Kheira, Solovei, Laurence, Hayot, Maurice, Gouzi, Fares, Serre, Isabelle, Molinari, Nicolas, and Bourdin, Arnaud

Published
2022
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24. Supplementary file on the standard rheometry data, microrheology complementary data, and mucus composition data from Mucus from human bronchial epithelial cultures: rheology and adhesion across length scales

Author

Jory, Myriam, Donnarumma, Dario, Blanc, Christophe, Bellouma, Karim, Fort, Aurélie, Vachier, Isabelle, Casanellas, Laura, Bourdin, Arnaud, and Massiera, Gladys

Abstract

The supplementary files contains detailed data mentionned in the main text on the standard rheometry results. The experiments limitations, the yield stress measurements and the non-linear (LAOS) measurements are described in details, as well as the response variability depending on the culture day. The micromanipulations performed with the optical tweezers are also detailed: The response dependance upon the probe size and materials is detailed, as well as the elastic moduli close to the interface. Fially, the mucus composition / rheology correlation can be evaluated on provided Figures, corresponding to the discussion in the main text.

Published
2022
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25. Generation of the induced pluripotent stem cell line UHOMi001-A from a patient with mutations in CCDC40 gene causing Primary Ciliary Dyskinesia (PCD)

Author

Ahmed, Engi, Sansac, Caroline, Fieldes, Mathieu, Bergougnoux, Anne, Bourguignon , Chloé, Mianne, Joffrey, Arnould, Cécile, Vachier, Isabelle, Assou, Said, Bourdin, Arnaud, John, De Vos, MORNET, Dominique, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), and Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDV] Life Sciences [q-bio], Adult, lcsh:Biology (General), [SDV]Life Sciences [q-bio], Induced Pluripotent Stem Cells, Mutation, Humans, Proteins, Female, lcsh:QH301-705.5, ComputingMilieux_MISCELLANEOUS, Ciliary Motility Disorders
Abstract

Primary Ciliary Dyskinesia (PCD) is a rare heterogeneous genetic disorder affecting motile cilia structure and function leading to lung disease. We generated induced pluripotent stem cells (iPSCs) from dermal fibroblasts of a female PCD patient carrying disease-causing variants in the CCDC40 gene. Reprogramming was performed with the human OSKM transcription factors using the Sendai-virus delivery system. The resulting transgene free iPSCs had normal karyotype, expressed pluripotency markers, could differentiate into the three germ layers in vivo and retained the disease-causing CCDC40 mutations. This iPSC line could be useful to model PCD disease and test gene therapy strategies.Resource TableUnlabelled TableUnique stem cell line identifierUHOMi001-AAlternative name(s) of stem cell lineiPCD02.30InstitutionInstitute for Regenerative Medicine & Biotherapy (IRMB), Montpellier, FRANCEContact information of distributorJohn De Vos john.devos@inserm.frType of cell lineiPSCOriginhumanAdditional origin infoAge: 34Sex: FemaleCell SourceDermal fibroblastsClonalityClonalMethod of reprogramminghOCT4, hSOX2, hC-MYC, hKLF4 (CytoTune™-iPS 2.0 Sendai Reprogramming Kit - Invitrogen, Thermo Fisher Scientific Inc.)Genetic ModificationYESType of ModificationSpontaneous mutationAssociated diseasePrimary Ciliary DyskinesiaGene/locusCompound Heterozygous mutations the Coiled-Coil Domain Containing 40 Gene (CCDC40): c.1116_1117delCT (Exon 7) and c.3180 + 1G > A (Intron 19)Method of modificationN/AName of transgene or resistanceN/AInducible/constitutive systemN/ADate archived/stock date2018-02-12Cell line repository/bankN/AEthical approvalThe study was approved by the regional scientific ethical committee (CPP Sud Med IV) under the number ID-RCB: 2013-A00892–43/CILIPS, Promoter University Hospital Of Montpellier) and informed consent was obtained from the patient.

Published
2018

27. Additional file 3: Table S2. of DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis

Author

Magalhães, Milena, Rivals, Isabelle, Claustres, Mireille, Varilh, Jessica, Thomasset, Mélodie, Bergougnoux, Anne, Mely, Laurent, Leroy, Sylvie, Corvol, Harriet, Guillot, Loïc, Murris, Marlène, Beyne, Emmanuelle, Caimmi, Davide, Vachier, Isabelle, Chiron, Raphaël, and Sario, Albertina De

Abstract

Distribution of HMOX1 and GSTM3 genotypes in CF patients and controls (DOCX 39 kb)

Published
2017
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28. Additional file 3: Table S2. of DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis

Author

Magalhães, Milena, Rivals, Isabelle, Claustres, Mireille, Varilh, Jessica, Thomasset, Mélodie, Bergougnoux, Anne, Mely, Laurent, Leroy, Sylvie, Corvol, Harriet, Guillot, Loïc, Murris, Marlène, Beyne, Emmanuelle, Caimmi, Davide, Vachier, Isabelle, Chiron, Raphaël, and Sario, Albertina De

Abstract

Distribution of HMOX1 and GSTM3 genotypes in CF patients and controls (DOCX 39 kb)

Published
2017
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29. Additional file 2: Figure S2. of DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis

Author

Magalhães, Milena, Rivals, Isabelle, Claustres, Mireille, Varilh, Jessica, Thomasset, Mélodie, Bergougnoux, Anne, Mely, Laurent, Leroy, Sylvie, Corvol, Harriet, Guillot, Loïc, Murris, Marlène, Beyne, Emmanuelle, Caimmi, Davide, Vachier, Isabelle, Chiron, Raphaël, and Sario, Albertina De

Subjects
body regions, nervous system, fungi
Abstract

DNA methylation distribution at 14 analyzed genes in CF and control samples. (PDF 212 kb)

Published
2017
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32. Additional file 1: Table SA1. of Rising total costs and mortality rates associated with admissions due to COPD exacerbations

Author

Molinari, Nicolas, Chanez, Pascal, Roche, Nicolas, Engi Ahmed, Vachier, Isabelle, and Bourdin, Arnaud

Subjects
respiratory tract diseases
Abstract

COPD hospitalizations and definitions of severity categories (sorting rules according to ICD-10) [17]. Table SA2. Leading cause associated with COPD admissions. Table SA3. Trends in admissions-related costs among different categories of severity. Table SA4. Cause of COPD admissions. Only five leading causes are mentioned. Table SA5. Top seven medical acts performed during hospitalizations for COPD exacerbations. 2007 and 2012 data and changes are presented. (DOCX 27Â kb)

Published
2016
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