1. Case of Kikuchi-Fujimoto disease associated with multiple myeloma
- Author
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Vidhi Unadkat, Siti Nadhirah Binti Abd Hadi, Ciro R. Rinaldi, and Luqman Safwan Fauzi
- Subjects
Axillary Lymph Node Biopsy ,medicine.medical_specialty ,Biopsy ,Lymphadenopathy ,Case Report ,Disease ,Monoclonal Gammopathy of Undetermined Significance ,03 medical and health sciences ,0302 clinical medicine ,immune system diseases ,hemic and lymphatic diseases ,Internal medicine ,medicine ,Humans ,030223 otorhinolaryngology ,Histiocytic Necrotizing Lymphadenitis ,Multiple myeloma ,030203 arthritis & rheumatology ,Hematology ,medicine.diagnostic_test ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Dermatology ,Rash ,medicine.anatomical_structure ,Female ,Bone marrow ,medicine.symptom ,Multiple Myeloma ,business ,Monoclonal gammopathy of undetermined significance - Abstract
We present a 47-year-old, South-African origin, woman with a background of stable monoclonal gammopathy of unknown significance (MGUS) who attended A&E with a history of coryzal symptoms associated with persistent fever, lymphadenopathy and a new onset of rash, not responding to antibiotics and paracetamol. A trial of high-dose steroids resolved symptoms. Bone marrow biopsy confirmed a progression of MGUS into multiple myeloma and her axillary lymph node biopsy analysis supported a diagnosis of Kikuchi-Fujimoto disease (KFD). This is an unusual presentation where KFD has been noted alongside MGUS progression to multiple myeloma. Haematology follow-up is underway.
- Published
- 2021
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