1. Prevalence and risk factors of carbapenem-resistant
- Author
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Bo, Guo, Ziqi, Guo, Huifeng, Zhang, Chuanchuan, Shi, Bingyu, Qin, Shanmei, Wang, Yinjiang, Chang, Jian, Chen, Peili, Chen, Limin, Guo, Weidong, Guo, Huaibin, Han, Lihong, Han, Yandong, Hu, Xiaoye, Jin, Yening, Li, Hong, Liu, Ping, Lou, Yibing, Lu, Panfeng, Ma, Yanhua, Shan, Yiyi, Sun, Wukui, Zhang, Xisheng, Zheng, and Huanzhang, Shao
- Abstract
In intensive care units (ICUs), carbapenem-resistantThis cross-sectional study was conducted in 96 ICUs of 78 hospitals in Henan Province, China. The clinical and microbiological data were collected. A multivariable logistic regression model was used to analyze the risk factors for CRE positivity.A total of 1,009 patients were enrolled. There was a significant difference in CRE positive rate between pharyngeal and anal swabs (15.16 vs. 19.13%,In ICUs in Henan Province, CRE positive rate was very high, mostly KPC-type CR-KPN. Patients with prolonged ICU stay, chronic neurological disease, transfer from other hospitals, previous infection, and history of antibiotic exposure are prone to CRE. Age and cardiovascular diseases are susceptibility factors for mixed infections of CRE. The CRE positive rate in tertiary hospitals was higher than that in secondary hospitals, which may be related to the source of patients, antibiotic exposure, disease severity, and previous infection.
- Published
- 2022