1. Recurrent fulminant hepatic failure in an HB carrier after intensive chemotherapy
- Author
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Hiroaki Okamoto, Yoshiba Makoto, Fumio Sugata, Toshiyuki Uchikoshi, Shogo Iwabuchi, Y. Tanaka, Masao Takatori, Kazuhiko Sekiyama, and Kazuaki Inoue
- Subjects
medicine.medical_specialty ,Hepatitis B virus ,Physiology ,Fulminant ,medicine.medical_treatment ,Molecular Sequence Data ,medicine.disease_cause ,Virus Replication ,Immunocompromised Host ,Fulminant hepatic failure ,Interferon ,Recurrence ,Internal medicine ,Cyclosporin a ,Antineoplastic Combined Chemotherapy Protocols ,medicine ,Humans ,Chemotherapy ,Base Sequence ,business.industry ,Lymphoma, Non-Hodgkin ,Gastroenterology ,Hepatology ,Middle Aged ,medicine.disease ,Hepatitis B ,Lymphoma ,Hepatic Encephalopathy ,Immunology ,Carrier State ,DNA, Viral ,Female ,business ,medicine.drug - Abstract
A 56-year-old female HB carrier developed fulminant hepatic failure with propagation of precore mutant hepatitis B virus following two sessions of intensive chemotherapy for non-Hodgkin's lymphoma. She was treated with interferon and cyclosporin A for the suppression of viral replication and enhanced host immune responses. She recovered from liver failure with histological evidence of marked regenerative activity.
- Published
- 1993