1. Impact of interstitial lung disease on mortality of patients with rheumatoid arthritis
- Author
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Jisoo Lee, Jung Yoon Choe, Seung Jae Hong, Hye Soon Lee, Joo Hyun Lee, Chan-Bum Choi, Tae-Hwan Kim, Tae-Jong Kim, Dam Kim, Yoon Kyoung Sung, Young Ok Jung, Jin Woo Song, Jae-Bum Jun, Shin-Seok Lee, Soo-Kyung Cho, Bo Young Yoon, Won Tae Chung, Dae Hyun Yoo, and Sang Cheol Bae
- Subjects
Adult ,Male ,medicine.medical_specialty ,Immunology ,Arthritis ,Comorbidity ,behavioral disciplines and activities ,Arthritis, Rheumatoid ,03 medical and health sciences ,0302 clinical medicine ,Rheumatology ,Internal medicine ,Prevalence ,medicine ,Humans ,Immunology and Allergy ,Prospective Studies ,Risk factor ,Prospective cohort study ,Survival rate ,Aged ,030203 arthritis & rheumatology ,business.industry ,Interstitial lung disease ,Middle Aged ,respiratory system ,medicine.disease ,respiratory tract diseases ,Surgery ,Survival Rate ,body regions ,030228 respiratory system ,Rheumatoid arthritis ,Cohort ,Female ,Radiography, Thoracic ,Lung Diseases, Interstitial ,Tomography, X-Ray Computed ,business - Abstract
To identify the prevalence of interstitial lung disease (ILD) in Korean patients with rheumatoid arthritis (RA) and assess its effect on mortality. A total of 3555 patients with RA, with chest X-ray or chest computed tomography (CT) data at enrollment were extracted from the KORean Observational study Network for Arthritis cohort, a nationwide prospective cohort for patients with RA in Korea. The patients were classified into two groups: (1) an ILD group by chest X-ray or chest CT scan, and (2) a non-ILD group by these modalities. After comparing the characteristics of the groups at enrollment, mortalities were compared using the log-rank test. To explore the impact of ILD on mortality, Cox proportional hazard models were used. Sixty-four patients (1.8%) were identified with ILD. Male and older patients were more common in the ILD group. During a mean follow-up of 24 months, 6 patients (9.4%) in the ILD group and 25 patients (0.7%) in the non-ILD group died; the survival rate was significantly worse in the ILD group (p
- Published
- 2017
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