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A cross-platform software application was developed to manage energy generation and consumption intelligently in smart homes. The system model consists of domestic loads, household distributed energy resources and an energy storage component that supports scheduled charging/discharging. The software deals with all these electrical devices as well as their energy information, based on which real-time conditions are presented to the resident and the history can be queried. Whats more, the application fulfills kinds of energy profiling and pricing-related optimization on account of demand response, resulting more monetary benefits and comforts. The software interacts smartly with energy owners by graphical user interface (GUI) and enables an intelligent electricity usage pattern in the context of smart power consumption within the framework of smart grid.

A novel series of thiazole acetamides was synthesized in excellent yields and characterized with the aid of various spectroscopic and elemental analysis. These compounds were evaluated for in vitro acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities for possible benefit in Alzheimers disease (AD). Among the synthesized compound, 6d was identified as the most potent compound of AChE (IC50=3.14±0.16 μM) with a selectivity index (SI) of 2.94 against BuChE. These compounds were further tested for inhibition of Aβ aggregation and β-secretase, where it showed potent inhibition which confirmed its multifactorial benefits in AD. The toxicity and docking study were also carried out to exemplify the pharmacological profile of compound 6d as prospective lead molecule against AD.