1. [Melanoma cutâneo metastático em um tigre-siberiano (Panthera tigris altaica) - relato de caso]
- Author
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C. Eckstein, H.P. Tinoco, C.M. Coelho, P.A. Lima, C.E.V. Rocha, and R.L. Santos
- Subjects
melanocytic neoplasia ,medicine.medical_specialty ,Pathology ,040301 veterinary sciences ,felinos de cativeiro ,melanoma cutâneo ,SF1-1100 ,Metastasis ,0403 veterinary science ,cutaneous melanoma ,03 medical and health sciences ,neoplasia melanocítica ,wild animals ,medicine ,030304 developmental biology ,0303 health sciences ,General Veterinary ,biology ,business.industry ,Melanoma ,captive felines ,Nodule (medicine) ,04 agricultural and veterinary sciences ,biology.organism_classification ,medicine.disease ,Animal culture ,animais silvestres ,Cutaneous melanoma ,Histopathology ,sense organs ,Lymph ,medicine.symptom ,business ,Corpora amylacea ,Siberian tiger - Abstract
A male 15-year-old captive Siberian tiger (Panthera tigris altaica) developed pelvic limb hypermetry over the past 10 years. Recently, an ulcerated black nodule located caudally to the right ear was observed. The animal was submitted to surgery for removing the tumor, but died during anesthetic recovery. At necropsy, another infiltrative nodule was observed caudally to the right ear. Histologically, both nodules corresponded to melanocytic neoplasia, varying from heavily pigmented to amelanotic, with metastasis to mediastinal lymph nodes, spleen and lung. Lipofuscinosis and corpora amylacea were histologically observed in the central nervous system. Macroscopic and histologic findings confirmed the diagnosis of skin metastatic melanoma in a captive adult Siberian tiger. RESUMO Um tigre-siberiano (Panthera tigris altaica) de cativeiro, macho, de 15 anos de idade, apresentou hipermetria dos membros pélvicos nos últimos 10 anos, e recentemente, foi observado um nódulo preto e ulcerado caudalmente à orelha direita. O animal foi submetido à cirurgia para remoção do nódulo e morreu durante a recuperação anestésica. À necropsia, outro nódulo infiltrativo, foi detectado caudalmente a orelha direita. Histologicamente, ambos os nódulos correspondiam à neoplasia melanocítica, com células variando de fortemente pigmentadas a amelanóticas, com metástase para linfonodos mediastinais, baço e pulmão. Havia lipofucsinose e corpora amilácea no sistema nervoso central. Os achados macroscópicos e histológicos confirmam o diagnóstico de melanoma cutâneo metastático em um tigre-siberiano adulto de cativeiro.
- Published
- 2020
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