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Guava is considered as poor man’s apple rich in phytochemicals with medicinal value and hence it is highly consumed. Gas chromatography–mass spectroscopy (GC–MS) analysis of guava leaf extract revealed the presence of various bioactive compounds with antimicrobial, antioxidant, anticancer, and antitumor properties. Hence, it is used in tooth paste formulations along with other ingredients such asAcacia arabicagum powder, stevia herb powder, sea salt, extra virgin coconut oil, peppermint oil in the present study. Three formulations F1, F2 and F3 have been made by varying the concentration of these ingredients and the prepared formulations were studied for their antimicrobial activity and physico-chemical parameters such as pH, abrasiveness, foaming activity, spreading and cleaning ability. Among these, F3 showed significant antioxidant and antimicrobial properties, minimal cytotoxicity, maximum spreadability and very high cleaning ability. This study surmises that the herbal toothpaste formulation is greener, rich in medicinal values and imparts oral hygiene.

Objectives: The aim of this study was to evaluate dentine permeability after brushing with Twin Lotus®, Thai herbal toothpaste by comparing with Sensodyne Rapid Relief®, a commercial desensitizing toothpaste, and also after artificial saliva (AS) immersion or citric acid challenge. Materials and Methods: Dentine discs from human mandibular third molars were divided into three groups (n = 20) and brushed with either experimental toothpaste or water (control) for 2 min with an automated toothbrush. Then, 10 discs were immersed in AS, and the other 10 discs were immersed in 6% citric acid to simulate the conditions of the oral environment. The dentine permeability of each specimen was measured before brushing and after each treatment using a fluid filtration system. Morphological changes in the dentine were observed using scanning electron microscopy (SEM). Results: Both toothpastes significantly reduced dentine permeability, and a crystalline precipitate was observed on the dentine surface under SEM observation. No significant difference was found between the two toothpaste groups with regard to dentine permeability after brushing and AS or acid immersion. Conclusions: The dentine permeability reduction caused by the two toothpastes did not differ after brushing or after AS or citric acid immersion.

Background: Use of antimicrobial agents is one of the important strategies to prevent oral diseases. These agents vary in their abilities to deliver preventive and therapeutic benefits. Objectives: This invitro study was conducted to assess antimicrobial efficacy of different toothpastes against various oral pathogens. Materials and Methods: A total of nine toothpastes in three groups were tested for their antimicrobial activity against Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 25923), Streptococcus mutans (ATCC 0266P) and Candida albicans (Laboratory Strain) by modified agar well diffusion method. Statistical Analysis was performed using Minitab Software. A p-value of less than 0.05 was considered significant. Results: Triclosan-based dental formulation with combination of fluoride (1000ppm) exhibited higher antimicrobial activity against test organisms than the combination of lower fluorideconcentration or sodium monofluorophosphate. Among herbal dentifrices, formulation containing Neem, Pudina, Long, Babool, Turmeric and Vajradanti showed significant antimicrobial activity against all the four tested microorganisms (p

Aim: The aim of this study was to compare the micro hardness of a nanohybrid composite resin after brushing with two herbal and one non-herbal whitening toothpastes. Materials and Methods: We divided Eighty disk-shaped specimens of a nanohybrid composite (Tetric N Ceram, Ivoclar Vivadent, Asia) into 4 groups of 20 specimens each: Groups A, B, C, and D. Group A was control, Group B was brushed with Colgate total advanced whitening (Colgate-Palmolive (India) Limited), Group C with Salt and Lemon, Dabur (Dabur International Limited, Dubai, UAE), and Group D with HiOra Shine, Himalaya (The Himalaya Drug Company, India). The specimens were polished using medium, fine, and superfine discs (Sof-lex, 3M, ESPE, USA) and subsequently placed at 37°C in distilled water. They were brushed for 2 minutes twice daily with a soft motorized toothbrush (Colgate 360 sonic power battery-operated tooth brush, Colgate Palmolive, India) for 30 days. The samples were rinsed under running water to remove the toothpaste and stored in distilled water at 37°C until the readout was taken on the Vickers's hardness tester for microhardness. Results: The results revealed that the difference among the groups was statistically significant (P < 0.001). Tukey's test showed that reduction in microhardness for Group B was significantly higher than that for Group C and Group D (P < 0.001). Conclusion: Within the limitations of this study, non-herbal whitening toothpaste had a greater impact on the microhardness of nanohybrid resin composite than herbal whitening toothpastes.

Maintaining good oral hygiene in orthodontic patients is important and as the community interest in herbal ingredients increases, herbal toothpaste was developed. Its effectiveness against dental plaque accumulation is still under debate. Herbal toothpaste has not been tested in fixed orthodontic patients. Objective: To study the effectivenes differences between herbal toothpaste and non-herbal toothpaste. Methods: This randomized, double blind clinical trial was participated by 16 subjects aged range 15-35 years who were planned for fixed orthodontic. The subjects were divided into two groups based on the type of toothpaste used. Plaque accumulations were measured according to Löe and Sillness plaque index on Ramfjord teeth before and two weeks after bonding. Results: Wilcoxon test result showed there was no significant reduction of plaque index on herbal toothpaste usage nor significant increase on non-herbal toothpaste usage. Mann-Whitney test showed no significant differences between herbal and non-herbal toothpaste. Conclusion: There was no significant differences in plaque acummulation between usage of herbal toothpaste nor usage of non-herbal toothpaste. There was no significant effectiveness differences between those toothpastes in fixed orthodontic patients, although herbal toothpaste usage showed a reduction of plaque index, whereas non-herbal toothpaste usage showed an increase of plaque index.DOI: 10.14693/jdi.v19i3.143

Orthodontic treatment with fixed appliance aims to improve esthetics and function of mastication and speech, however the components on a fixed appliance as bands, brackets and ligatures may increase the amount of plaque as the primary etiology of gingivitis. Objective: a double-blind study of randomized clinical trial was designed to investigate the effectiveness of herbal toothpaste against gingivitis as compared with conventional toothpaste in orthodontic patients with fixed appliance. Methods: Sixteen subjects before the application of fixed orthodonitc appliance was selected based on inclusion criteria. They were then randomized using block randomization method and divided into the test group and the control group. Gingival index of Löe and Sillness examined before brackets bonding and two weeks after. Paired t-test was used to compare the differences within the groups and unpaired t-test was used to compare the differences between groups at baseline and two weeks after. Results: There was a tendency of decreasing in gingival index but there were no significant differences between before and after the application of fixed appliance in the herbal toothpaste group. There was a tendency of increasing in gingival index and there were significant differences between before and after the application of fixed appliance in the conventional toothpaste group. There was significant differences between the two groups. Conclusion: There was significant difference between the two grouups, herbal indicates effectiveness in gingivitis control after the application of fixed orthodontic appliance, so it sould be used as an alternative natural based toothpaste in overcoming gigngivitis in orthodontic patients with fixed appliance.

Karies gigi dan penyakit periodontal dapat dicegah dengan mengontrol pembentukan plak secara teratur. Penggunaan pasta gigi herbal dapat memberikan efek kimia untuk mengontrol pembentukan plak. Studi terdahulu mendapatkan bahwa pasta gigi herbal dapat mengurangi jumlah bakteri utama pada rongga mulut yaitu Streptococcus mutans. Penelitian ini bertujuan untuk meneliti perbedaan daya hambat beberapa pasta gigi herbal (mengandung siwak, cengkeh, dan daun sirih) terhadap pertumbuhan Streptococcus mutans. Metode penelitian adalah eksperimental dengan meletakkan cakram yang sudah direndam dengan pasta gigi ke medium agar darah yang mengandung koloni Streptococcus mutans. Uji daya hambat bakteri dilakukan dengan metode difusi. Terbentuknya zona bening di sekitar koloni bakteri menunjukkan adanya penghambatan pertumbuhan bakteri uji. Hasil uji satu arah ANOVA menunjukkan adanya perbedaan daya hambat yang bermakna antar pasta gigi herbal yang digunakan (pAbstractDental caries and periodontal disease can be eliminated by regularly control plaque formation. The usage of herbal toothpaste is able to give chemical effect toward plaque control. Previous studies shown that the usage of herbal toothpaste was able to reduce the growth of Streptococcus mutans, the main bacteria in the mouth. The study aimed at investigating the difference of zone of inhibition of several herbal toothpastes (siwak- , cloves- , and betel leaves- contained) toward the growth of Streptococcus mutans.This study was experimental research using disc that had been immersed and subsequently put it onto Blood agar medium that contain Streptococcus mutans. Inhibition test of the growth of bacteria was done by using diffusion method and was said as positif result when clear zone surrounding the colony of Streptococcus mutans was identified. One way ANOVA test result showed there was a significant difference of inhibition effect among those three herbal toothpaste (p

Introduction: Dental plaque is a well-known etiologic factor for gingivitis. Ayurvedic drugs have been used since ancient times to treat diseases including periodontal diseases. Toothpastes made from herbal medicines are used in periodontal therapy to control bleeding and reduce inflammation. Aim: To compare the effectiveness of herbal and nonherbal fluoridated toothpaste on plaque and gingivitis among residents of ladies hostel in Mathura City. Materials and Methods: A randomized controlled clinical trial was carried out on 60 participants aged 18-30 years residing in a ladies hostel of Mathura City. The 60 participants were randomly allocated into two groups: Group-I: Experimental group using herbal toothpaste, Group-II: Control group using fluoridated toothpaste. The subjects were asked to brush twice daily with the assigned dentifrice using standardized brushing technique for 46 days. The plaque and gingival indices were recorded according to Silness and Loe (1964) and Loe and Silness (1963), respectively. These parameters were assessed at baseline, 3 weeks, and 6 weeks. Data were analyzed by Student paired t-test and unpaired t-test using Statistical Package for the Social Sciences version 21 manufactured by IBM Corporation - Armonk, New York, US. Results: Baseline plaque and gingival scores were found 1.02 ± 0.02 and 0.88 ± 0.06 for the experimental group and 1.02 ± 0.03 and 0.81 ± 0.08 for control group, respectively. After 6 weeks plaque and gingival scores were found 0.77 ± 0.07 and 0.72 ± 0.08 for experimental group and 0.78 ± 0.07 and 0.73 ± 0.11 for control group, respectively. Statistically significant differences were obtained before and after intervention in both groups (P ≤ 0.05). Conclusion: The herbal toothpaste was as effective as the conventionally formulated fluoride dentifrice in controlling plaque and gingivitis.

Objective: A double-blinded controlled clinical trial with parallel groups was designed to investigate the effectiveness of a herbal-based toothpaste in the control of plaque and gingivitis as compared with a conventional dentifrice. The efficacy of Colgate Herbal over Colgate tooth paste was assessed in this study. Materials and Methods: Thirty subjects with gingivitis participated in the study. All participants had at least 20 natural teeth with no probing depths greater than 3 mm and a plaque index score of 2 or more at baseline. At baseline, the clinical parameters like gingival index, plaque index and salivary pH were estimated. Paired t-test was used to compare the difference within the groups and unpaired t-test was used to compare the difference between the groups at baseline and on the 30 th day. Results: At the end of the study, there were statistically significant reductions in the gingival index and the plaque index scores within the test group. However, there were no statistically significant differences between the test and the control groups. The salivary pH changes were not statistically significant in the test group but were displaced more toward the acidic range in the control group. Conclusion: It was however concluded that the herbal-based toothpaste was as effective as the conventionally formulated dentifrice in the control of plaque and gingivitis.