1. Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures
- Author
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Joon Kiong Lee, Kenneth G. Saag, Weibo Xia, O. Mkinsi, F. Jiwa, Helena Johansson, Daniel Prieto-Alhambra, Enwu Liu, Nicholas C. Harvey, Mattias Lorentzon, C. Campusano, Bess Dawson-Hughes, Olivier Bruyère, Daniel Pinto, Nicola Veronese, Cyrus Cooper, René Rizzoli, L. Zakraoui, Jean-Yves Reginster, Manju Chandran, Kassim Javaid, Nasser M. Al-Daghri, Eugene V. McCloskey, Demetrio Messina, Gemma Adib, J. A. Kanis, Kanis, J.A., Harvey, N.C., McCloskey, E., Bruyère, O., Veronese, N., Lorentzon, M., Cooper, C., Rizzoli, R., Adib, G., Al-Daghri, N., Campusano, C., Chandran, M., Dawson-Hughes, B., Javaid, K., Jiwa, F., Johansson, H., Lee, J.K., Liu, E., Messina, D., Mkinsi, O., Pinto, D., Prieto-Alhambra, D., Saag, K., Xia, W., Zakraoui, L., and Reginster, J.-Y.
- Subjects
0301 basic medicine ,medicine.medical_specialty ,FRAX ,Endocrinology, Diabetes and Metabolism ,education ,Osteoporosis ,Psychological intervention ,inhibitors of bone resorption ,030209 endocrinology & metabolism ,Risk Assessment ,Anabolic agents ,03 medical and health sciences ,Therapeutic approach ,0302 clinical medicine ,Bone Density ,Risk Factors ,Treatment of osteoporosis ,Internal medicine ,medicine ,fracture risk assessment ,Humans ,anabolic agents ,Intensive care medicine ,Osteoporosis, Postmenopausal ,Aged ,Anabolic agents, Fracture risk assessment, FRAX, Inhibitors of bone resorption, Treatment of osteoporosis ,ddc:616 ,Postmenopausal women ,business.industry ,Correction ,Fracture risk assessment ,Inhibitors of bone resorption ,Middle Aged ,treatment of osteoporosis ,medicine.disease ,Rheumatology ,Increased risk ,Female ,Position Paper ,030101 anatomy & morphology ,business ,Very high risk ,Algorithms ,Osteoporotic Fractures - Abstract
Summary Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures. Introduction The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2019. This manuscript seeks to apply this in an international setting, taking additional account of further categorisation of increased risk of fracture, which may inform choice of therapeutic approach. Methods Clinical perspective and updated literature search. Results The following areas are reviewed: categorisation of fracture risk and general pharmacological management of osteoporosis. Conclusions A platform is provided on which specific guidelines can be developed for national use to characterise fracture risk and direct interventions.
- Published
- 2019