1. Prehospital on-scene anaesthetist treating severe traumatic brain injury patients is associated with lower mortality and better neurological outcome
- Author
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Tom Silfvast, Heini Huhtala, Jouni Nurmi, Toni Pakkanen, Clinicum, Department of Diagnostics and Therapeutics, University of Helsinki, HUS Emergency Medicine and Services, Anestesiologian yksikkö, HUS Perioperative, Intensive Care and Pain Medicine, Yhteiskuntatieteiden tiedekunta - Faculty of Social Sciences, and Tampere University
- Subjects
Male ,Emergency Medical Services ,medicine.medical_treatment ,Prehospital emergency care (MeSH) ,Airway management (MeSH) ,Endotracheal intubation (MeSH) ,GUIDELINES ,Critical Care and Intensive Care Medicine ,0302 clinical medicine ,Anesthesiology ,Brain Injuries, Traumatic ,Epidemiology ,Emergency medical services ,Terveystiede - Health care science ,EPIDEMIOLOGY ,Intubation ,030212 general & internal medicine ,Hypoxia ,Original Research ,Head injury ,lcsh:Medical emergencies. Critical care. Intensive care. First aid ,Middle Aged ,Prognosis ,ADMISSION ,3. Good health ,Treatment Outcome ,EMERGENCY MEDICAL-SERVICES ,SURVIVAL ,Emergency Medicine ,Female ,Hypotension ,Neurotieteet - Neurosciences ,Traumatic brain injury (MeSH) ,Adult ,medicine.medical_specialty ,Prognostic variable ,Traumatic brain injury ,Critical care (MeSH) ,Patient outcome assessment (MeSH) ,03 medical and health sciences ,MANAGEMENT ,medicine ,Humans ,Glasgow Coma Scale ,Glasgow outcome scale (MeSH) ,Patient Care Team ,business.industry ,Emergency medical services (MeSH) ,030208 emergency & critical care medicine ,lcsh:RC86-88.9 ,3126 Surgery, anesthesiology, intensive care, radiology ,medicine.disease ,Blood pressure ,INTUBATION ,Emergency medicine ,business ,SYSTOLIC BLOOD-PRESSURE ,COMA SCALE SCORE - Abstract
Background Patients with isolated traumatic brain injury (TBI) are likely to benefit from effective prehospital care to prevent secondary brain injury. Only a few studies have focused on the impact of advanced interventions in TBI patients by prehospital physicians. The primary end-point of this study was to assess the possible effect of an on-scene anaesthetist on mortality of TBI patients. A secondary end-point was the neurological outcome of these patients. Methods Patients with severe TBI (defined as a head injury resulting in a Glasgow Coma Score of ≤8) from 2005 to 2010 and 2012–2015 in two study locations were determined. Isolated TBI patients transported directly from the accident scene to the university hospital were included. A modified six-month Glasgow Outcome Score (GOS) was defined as death, unfavourable outcome (GOS 2–3) and favourable outcome (GOS 4–5) and used to assess the neurological outcomes. Binary logistic regression analysis was used to predict mortality and good neurological outcome. The following prognostic variables for TBI were available in the prehospital setting: age, on-scene GCS, hypoxia and hypotension. As per the hypothesis that treatment provided by an on-scene anaesthetist would be beneficial to TBI outcomes, physician was added as a potential predictive factor with regard to the prognosis. Results The mortality data for 651 patients and neurological outcome data for 634 patients were available for primary and secondary analysis. In the primary analysis higher age (OR 1.06 CI 1.05–1.07), lower on-scene GCS (OR 0.85 CI 0.79–0.92) and the unavailability of an on-scene anaesthetist (OR 1.89 CI 1.20–2.94) were associated with higher mortality together with hypotension (OR 3.92 CI 1.08–14.23). In the secondary analysis lower age (OR 0.95 CI 0.94–0.96), a higher on-scene GCS (OR 1.21 CI 1.20–1.30) and the presence of an on-scene anaesthetist (OR 1.75 CI 1.09–2.80) were demonstrated to be associated with good patient outcomes while hypotension (OR 0.19 CI 0.04–0.82) was associated with poor outcome. Conclusion Prehospital on-scene anaesthetist treating severe TBI patients is associated with lower mortality and better neurological outcome.
- Published
- 2019
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