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Packet loss-resilient and security are two major challenges faced by real-time audio transmission over IP networks. Due to the capability of recovering the signal from a small set of samplings and the randomness in the acquisition process, compressive sensing (CS) has a vast prospect in dealing with these problems. In this paper, we propose a secure and packet loss-resistant real-time audio transmission framework (CS-SPT) based on the principle of CS. Inspired by the interleaving technique, an ultralow complexity scrambling matrix was adopted in the proposed CS-SPT to improve its packet loss-resilient capability by increasing the information redundancy. Moreover, the energy of ciphertext is homogenized using a diffusion operation. Experimental results show that compared with existing methods, the proposed CS-SPT not only improves the packet loss-resilient ability significantly but also can resist several major attacks, such as COAs and KPAs.

In recent years, neuroimaging studies have remarkably demonstrated the presence of cognitive motor dissociation in patients with disorders of consciousness (DoC). These findings accelerated the development of brain–computer interfaces (BCIs) as clinical tools for behaviorally unresponsive patients. This article reviews the recent progress of BCIs in patients with DoC and discusses the open challenges. In view of the practical application of BCIs in patients with DoC, four aspects of the relevant literature are introduced: consciousness detection, auxiliary diagnosis, prognosis, and rehabilitation. For each aspect, the paradigm design, brain signal processing methods, and experimental results of representative BCI systems are analyzed. Furthermore, this article provides guidance for BCI design for patients with DoC and discusses practical challenges for future research.

Purpose Based on a theoretical framework of ambidexterity in technology sourcing beyond organizational and technological boundaries, this study aims to explore how start-ups balance technology sourcing in organizational ambidexterity (TSOA) to produce high venture performance. Design/methodology/approach A questionnaire survey is distributed among start-ups in the science and technology park of a university in eastern China, producing a total of 45 valid responses. The fuzzy-set approach to qualitative comparative analysis is used in this study. Findings The findings show that start-ups achieve high venture performance through external technology sourcing (external exploration and exploitation) in the initial stage. In the growth stage, start-ups adopt external and internal technology sourcing (internal exploration and exploitation) to produce high venture performance. The technology sourcing strategy in ambidextrous activity for start-ups is punctuated equilibrium and evolving from the external ambidexterity to internally and externally coordinate ambidexterity at entrepreneurial stages. Originality/value This study creatively adopts configuration-based thinking to investigate how to balance TSOA for high venture performance, extending the literature on technology sourcing and contributing to the balance theory of exploration and exploitation.

Multimodal emotion recognition in conversational videos (ERC) develops rapidly in recent years. To fully extract the relative context from video clips, most studies build their models on the entire dialogues which make them lack of real-time ERC ability. Different from related researches, a novel multimodal emotion recognition model for conversational videos based on reinforcement learning and domain knowledge (ERLDK) is proposed in this paper. In ERLDK, the reinforcement learning algorithm is introduced to conduct real-time ERC with the occurrence of conversations. The collection of history utterances is composed as an emotion-pair which represents the multimodal context of the following utterance to be recognized. Dueling deep-Q-network (DDQN) based on gated recurrent unit (GRU) layers is designed to learn the correct action from the alternative emotion categories. Domain knowledge is extracted from public dataset based on the former information of emotion-pairs. The extracted domain knowledge is used to revise the results from the RL module and is transformed into other dataset to examine the rationality. The experimental results on datasets show that ERLDK achieves the state-of-the-art results on weighted average and most of the specific emotion categories.

Grant-free non-orthogonal multiple access (NOMA) has recently received wide attention for reducing signaling overhead and transmission latency in massive machine-type communications (mMTC). In grant-free NOMA systems, user activity and data (UAD) has to be detected, which is challenging in practice. As an emerging technique, compressive sensing (CS) shows great promise in solving this problem by exploiting the inherent sparsity nature of user activity. This paper proposes to use the weighted l2,1 minimization (WL21M) to jointly detect UAD in realistic dynamic scenarios. At first, the average recoverability of the WL21M is analyzed. This analysis reveals the fact that the WL21M can improve the detection performance by means of an appropriate weighting and the incorporation of intrinsic temporal correlation. Motivated by the analysis, a collaborative hierarchical match pursuit (C-HiMP) algorithm is proposed for dynamic UAD detection. In the C-HiMP, a sequence of WL21M problems are solved in the subspaces spanned by all of the components in the hierarchical estimated support sets, where the weights are collaboratively updated by the solutions in previous time slots so that an attractive self-correction capacity is obtained. Simulation results demonstrate that the proposed C-HiMP can obtain significant performance improvements, in terms of detection accuracy and computational complexity, compared with several state-of-the-art CS-based detection algorithms.

Accurate reconstruction of cortical activation from electroencephalography and magnetoencephalography (E/MEG) is a long-standing challenge because of the inherently ill-posed inverse problem. In this paper, a novel algorithm under the empirical Bayesian framework, source imaging with smoothness in spatial and temporal domains (SI-SST), is proposed to address this issue. In SI-SST, current sources are decomposed into the product of spatial smoothing kernel, sparseness encoding coefficients, and temporal basis functions (TBFs). Further smoothness is integrated in the temporal domain with the employment of an underlying autoregressive model. Because sparseness encoding coefficients are constructed depending on overlapped clusters over cortex in this model, we derived a novel update rule based on fixed-point criterion instead of the convexity based approach which becomes invalid in this scenario. Entire variables and hyper parameters are updated alternatively in the variational inference procedure. SI-SST was assessed by multiple metrics with both simulated and experimental datasets. In practice, SI-SST had the superior reconstruction performance in both spatial extents and temporal profiles compared to the benchmarks.

Proteinuria or nephrotic syndrome are symptoms of podocytopathies, kidney diseases caused by direct or indirect podocyte damage. Human health worldwide is threatened by diabetic nephropathy (DN), the leading cause of end-stage renal disease (ESRD) in the world. DN development and progression are largely dependent on inflammation. The effects of podocyte damage on metabolic disease and inflammatory disorders have been documented. Epigenetic and endoplasmic reticulum (ER) stress are also evident in DN. Targeting inflammation pathway and ER stress in podocytes may be a prospective therapy to prevent the progression of DN. Here, we review the mechanism of epigenetics and ER stress on podocyte inflammation and apoptosis, and discuss the potential amelioration of podocytopathies by regulating epigenetics and ER stress as well as by targeting inflammatory signaling, which provides a theoretical basis for drug development to ameliorate DN.

With the increased concern over environment protection, cellulose acetate (CA) has drawn great interests as an alternative for packaging material due to its biodegradability and abundant resources; whereas, the poor antistatic property and thermal conductivity restrict its application in packaging. In this work, we propose a simple but effective strategy to produce high performance graphene nanoplatelet (GNP)/CA composite films via the consecutive homogenization and solvent cast processes. Relying on the spontaneous absorption of CA during homogenization, the GNP/CA produced shows an excellent dispersibility in the N,N-Dimethylformamide (DMF) solution and much less structural defects compared with GNP alone. As a result, the composite film obtained shows simultaneously and significantly enhanced antistatic, heat dissipative and mechanical properties compared to the CA case. Specifically, the GNP/CA composite with the optimal formula produced has promising overall performances (namely, surface resistivity of 1.14×107 Ω/sq, in-plane thermal conductivity of 5.359 W · m-1 · K-1, out-of-plane thermal conductivity of 0.785 W · m-1 · K-1, and tensile strength of 37.1 MPa). Featured by its promising overall properties, simple production processes and biodegradability, the as-prepared GNP/CA composite film shows a great potential for application in packaging.

Recognizing human emotions based on electroencephalogram (EEG) signals has received a great deal of attentions. Most of the existing studies focused on offline analysis, and real-time emotion recognition using a brain computer interface (BCI) approach remains to be further investigated. In this paper, we proposed an EEG-based BCI system for emotion recognition. Specifically, two classes of video clips that represented positive and negative emotions were presented to the subjects one by one, while the EEG data were collected and processed simultaneously, and instant feedback was provided after each clip. Ten healthy subjects participated in the experiment and achieved a high average online accuracy of 91.5% ± 6.34%. The experimental results demonstrated that the subjects emotions had been sufficiently evoked and efficiently recognized by our system. Clinically, patients with disorder of consciousness (DOC), such as coma, vegetative state, and minimally conscious state, suffer from motor impairment and generally cannot provide adequate emotion expressions. Therefore, we applied our emotion recognition BCI system to patients with DOC. Eight DOC patients participated in our experiment, and three of them achieved significant online accuracy. The experimental results show that the proposed BCI system could be a promising tool to detect the emotional states of patients with DOC.

Cell heterogeneity has impeded the accurate interpretation of the bulk transcriptome data from patients with diabetic nephropathy (DN). We performed an analysis by integrating bulk and single-cell transcriptome datasets to uncover novel mechanisms leading to DN, especially in the podocytes. Microdissected glomeruli and tubules transcriptome datasets were selected from Gene Expression Omnibus (GEO). Then the consistency between datasets was evaluated. The analysis of the bulk dataset and single-nucleus RNA dataset was integrated to reveal the cell type-specific responses to DN. The candidate genes were validated in kidney tissues from DN patients and diabetic mice. We compared 4 glomerular and 4 tubular datasets and found considerable discrepancies among datasets regarding the deferentially expressed genes (DEGs), involved signaling pathways, and the hallmark enrichment profiles. Deconvolution of the bulk data revealed that the variations in cell-type proportion contributed greatly to this discrepancy. The integrative analysis uncovered that the dysregulation of spermatogenesis-related genes, including TEKT2 and PIAS2, was involved in the development of DN. Importantly, the mRNA level of TEKT2 was negatively correlated with the mRNA levels of NPHS1 (r = -.66, p .0001) and NPHS2 (r = -.85, p .0001) in human diabetic glomeruli. Immunostaining confirmed that the expression of TEKT2 and PIAS2 were up-regulated in podocytes of DN patients and diabetic mice. Knocking down TEKT2 resisted high glucose-induced cytoskeletal remodeling and down-regulation of NPHS1 protein in the cultured podocyte. In conclusion, the integrative strategy can help us efficiently use the publicly available transcriptomics resources. Using this approach and combining it with classical research methods, we identified TEKT2 and PIAS2, two spermatogenesis-related genes involved in the pathogenesis of DN. Furthermore, TEKT2 is involved in this pathogenesis by regulating the podocyte cytoskeleton.

As one of the new liberal arts categories, law has always been a key subject of national legal construction. With the continuous development of science and technology and the rapid progress of society, enterprises' demand for legal talents has changed from single type to compound type. The current training mode of legal talents in our country cannot meet the needs of the rapid development of the society. In view of this, combined with the traditional theoretical teaching mode of talent training for law majors, the new talent training methods should be added to explore the suitable mode for the cultivation of innovative and entrepreneurial talent for law majors in China. Starting from the theory and practice, combining with the characteristics of each university, the ultimate goal is to cultivate the compound legal talents with innovative and entrepreneurial ability.

Stereoelectroencephalography (SEEG) signals can be obtained by implanting deep intracranial electrodes. SEEG depth electrodes can record brain activity from the shallow cortical layer and deep brain structures, which is not achievable through other recording techniques. Moreover, SEEG has the advantage of a high signal-to-noise ratio (SNR). Therefore, it provides a potential way to establish a highly efficient brain-computer interface (BCI) and aid in understanding human brain activity. In this study, we implemented a P300-based BCI using SEEG signals. A single-character oddball paradigm was applied to elicit P300. To predict target characters, we fed the feature vectors extracted from the signals collected by five SEEG contacts into a Bayesian linear discriminant analysis (BLDA) classifier. Thirteen epileptic patients implanted with SEEG electrodes participated in the experiment and achieved an average online spelling accuracy of 93.85%. Moreover, through single-contact decoding analysis and simulated online analysis, we found that the SEEG-based BCI system achieved a high performance even when using a single signal channel. Furthermore, contacts with high decoding accuracies were mainly distributed in the visual ventral pathway, especially the fusiform gyrus (FG) and lingual gyrus (LG), which played an important role in building P300-based SEEG BCIs. These results might provide new insights into P300 mechanistic studies and the corresponding BCIs.

Multimodal sentiment analysis is one of the most attractive interdisciplinary research topics in artificial intelligence (AI). Different from other classification issues, multimodal sentiment analysis of human is a much finer classification problem. However, most current work accept all multimodalities as the input together and then output final results at one time after fusion and decision processes. Rare models try to divide their models into more than one fusion modules with different fusion strategies for better adaption of different tasks. Additionally, most recent multimodal sentiment analysis methods pay great focuses on binary classification, but the accuracy of multi-classification still remains difficult to improve. Inspired by the emotional processing procedure in cognitive science, both binary and multi-classification abilities are improved in our method by dividing the complicated problem into smaller issues which are easier to be handled. In this paper, we propose a Hierarchal Attention-BiLSTM (Bidirectional Long-Short Term Memory) model based on Cognitive Brain limbic system (HALCB). HALCB splits the multimodal sentiment analysis into two modules responsible for two tasks, the binary classification and the multi-classification. The former module divides the input items into two categories by recognizing their polarity and then sends them to the latter module separately. In this module, Hash algorithm is utilized to improve the retrieve accuracy and speed. Correspondingly, the latter module contains a positive sub-net dedicated for positive inputs and a negative sub-nets dedicated for negative inputs. Each of these binary module and two sub-nets in multi-classification module possesses different fusion strategy and decision layer for matching its respective function. We also add a random forest at the final link to collect outputs from all modules and fuse them at the decision-level at last. Experiments are conducted on three datasets and compare the results with baselines on both binary classification and multi-classification tasks. Our experimental results surpass the state-of-the-art multimodal sentiment analysis methods on both binary and multi-classification by a big margin.

Background This study aimed to develop and validate a deep learning (DL) model to identify atelectasis and attic retraction pocket in cases of otitis media with effusion (OME) using multi-center otoscopic images. Method A total of 6393 OME otoscopic images from three centers were used to develop and validate a DL model for detecting atelectasis and attic retraction pocket. A threefold random cross-validation procedure was adopted to divide the dataset into training validation sets on a patient level. A team of otologists was assigned to diagnose and characterize atelectasis and attic retraction pocket in otoscopic images. Receiver operating characteristic (ROC) curves, including area under the ROC curve (AUC), accuracy, sensitivity, and specificity were used to assess the performance of the DL model. Class Activation Mapping (CAM) illustrated the discriminative regions in the otoscopic images. Results Among all OME otoscopic images, 3564 (55.74%) were identified with attic retraction pocket, and 2460 (38.48%) with atelectasis. The diagnostic DL model of attic retraction pocket and atelectasis achieved a threefold cross-validation accuracy of 89% and 79%, AUC of 0.89 and 0.87, a sensitivity of 0.93 and 0.71, and a specificity of 0.62 and 0.84, respectively. Larger and deeper cases of atelectasis and attic retraction pocket showed greater weight, based on the red color depicted in the heat map of CAM. Conclusion The DL algorithm could be employed to identify atelectasis and attic retraction pocket in otoscopic images of OME, and as a tool to assist in the accurate diagnosis of OME.

Compressive sensing (CS) aims to accurately reconstruct high-dimensional signals from a small number of measurements by exploiting signal sparsity and structural priors. However, signal priors utilized in existing CS reconstruction algorithms rely mainly on hand-crafted design, which often cannot offer the best sparsity-undersampling tradeoff because high-order structural priors of signals are hard to be captured in this manner. In this article, a new recovery guarantee of the unified CS reconstruction model-weighted $\ell _{1}$ minimization (WL1M) is derived, which indicates universal priors could hardly lead to the optimal selection of the weights. Motivated by the analysis, we propose a deep unfolding network for the general WL1M model. The proposed deep unfolding-based WL1M (D-WL1M) integrates universal priors with learning capability so that all of the parameters, including the crucial weights, can be learned from training data. We demonstrate the proposed D-WL1M outperforms several state-of-the-art CS-based methods and deep learning-based methods by a large margin via the experiments on the Caltech-256 image data set.

Achieving high classification performance in electroencephalogram (EEG)-based brain-computer interfaces (BCIs) often entails a large number of channels, which impedes their use in practical applications. Despite the previous efforts, it remains a challenge to determine the optimal subset of channels in a subject-specific manner without heavily compromising the classification performance. In this article, we propose a new method, called spatiotemporal-filtering-based channel selection (STECS), to automatically identify a designated number of discriminative channels by leveraging the spatiotemporal information of the EEG data. In STECS, the channel selection problem is cast under the framework of spatiotemporal filter optimization by incorporating a group sparsity constraints, and a computationally efficient algorithm is developed to solve the optimization problem. The performance of STECS is assessed on three motor imagery EEG datasets. Compared with state-of-the-art spatiotemporal filtering algorithms using full EEG channels, STECS yields comparable classification performance with only half of the channels. Moreover, STECS significantly outperforms the existing channel selection methods. These results suggest that this algorithm holds promise for simplifying BCI setups and facilitating practical utility.

Fusion of multimodal features is a momentous problem for video emotion recognition. As the development of deep learning, directly fusing feature matrixes of each mode through neural networks at feature level becomes mainstream method. However, unlike unimodal issues, for multimodal analysis, finding the correlations between different modal is as important as discovering effective unimodal features. To make up the deficiency in unearthing the intrinsic relationships between multimodal, a novel modularized multimodal emotion recognition model based on deep canonical correlation analysis (MERDCCA) is proposed in this letter. In MERDCCA, four utterances are gathered as a new group and each utterance contains text, audio and visual information as multimodal input. Gated recurrent unit layers are used to extract the unimodal features. Deep canonical correlation analysis based on encoder-decoder network is designed to extract cross-modal correlations by maximizing the relevance between multimodal. The experiments on two public datasets show that MERDCCA achieves the better results.

A brain-computer interface (BCI) measures and analyzes brain activity and converts this activity into computer commands to control external devices. In contrast to traditional BCIs that require a subject-specific calibration process before being operated, a subject-independent BCI learns a subject-independent model and eliminates subject-specific calibration for new users. However, building subject-independent BCIs remains difficult because electroencephalography (EEG) is highly noisy and varies by subject. In this study, we propose an invariant pattern learning method based on a convolutional neural network (CNN) and big EEG data for subject-independent P300 BCIs. The CNN was trained using EEG data from a large number of subjects, allowing it to extract subject-independent features and make predictions for new users. We collected EEG data from 200 subjects in a P300-based spelling task using two different types of amplifiers. The offline analysis showed that almost all subjects obtained significant cross-subject and cross-amplifier effects, with an average accuracy of more than 80%. Furthermore, more than half of the subjects achieved accuracies above 85%. These results indicated that our method was effective for building a subject-independent P300 BCI, with which more than 50% of users could achieve high accuracies without subject-specific calibration.

The presence of organic contaminants in wastewater poses considerable risks to the health of both humans and ecosystems. Although advanced oxidation processes that rely on highly reactive radicals to destroy organic contaminants are appealing treatment options, substantial energy and chemical inputs limit their practical applications. Here we demonstrate that Cu single atoms incorporated in graphitic carbon nitride can catalytically activate H2O2 to generate hydroxyl radicals at pH 7.0 without energy input, and show robust stability within a filtration device. We further design an electrolysis reactor for the on-site generation of H2O2 from air, water and renewable energy. Coupling the single-atom catalytic filter and the H2O2 electrolytic generator in tandem delivers a wastewater treatment system. These findings provide a promising path toward reducing the energy and chemical demands of advanced oxidation processes, as well as enabling their implementation in remote areas and isolated communities.

From a novel historical angle, this paper examines a fundamental question of why bribery is so prevalent throughout Vietnamese history, why it has become a culturally acceptable norm, and what hist...

Spectral–spatial Gabor filtering, which is based on 3-D local harmonic analysis, has been a powerful spectral–spatial feature extraction tool for hyperspectral image (HSI) classification. However, existing spectral–spatial Gabor approaches are prone to oversmoothing, neglecting the existences of edges and negatively affecting the classification. In this article, we propose a new HSI Gabor filtering concept, called spectral–spatial-range Gabor filtering, which intends to restrain edge interference from disturbing local spectral–spatial harmonic components. Contributions and novelties of our work can be identified as follows: 1) an HSI filtering framework is created, which can accommodate various Gabor filtering procedures and hence offer the potential to guide the design of new Gabor filters; 2) following such a unified filtering framework and taking into consideration both local spectral–spatial harmonic characteristics and range domain variations, we develop a new concept of spectral–spatial-range Gabor filtering; and 3) utilizing this proposed Gabor prototype and elaborating mathematical derivations, we achieve a novel discriminative spectral–spatial-range Gabor filtering method, which can deal with discriminative local harmonics and edge interference simultaneously along the spectral–spatial-range domain, obtaining highly discriminative Gabor features while yielding linear computational complexity. Our novel method is evaluated on four real HSI data sets and achieves excellent performances.

Estimating the extents and localizations of extended sources from noninvasive EEG/MEG signals is challenging. In this paper, we have proposed a fully data driven source imaging method, namely Variation Sparse Source Imaging based on Automatic Relevance Determination (VSSI-ARD), to reconstruct extended cortical activities. VSSI-ARD explores the sparseness of current sources on the variation domain by employing ARD prior under empirical Bayesian framework. With convex analysis, the sources are efficiently obtained by solving a series of reweighting L21-norm regularization problems with ADMM. By virtue of the iterative reweighting process and sparse signal processing techniques, VSSI-ARD gets rid of the small amplitude dipoles that are more probably outside the extent of underlying sources. With the sparsity enforced on the edges using ARD prior, the estimations show clear boundaries between active and background regions without subjective thresholds. Validation with both simulated and human experimental data indicates that VSSI-ARD not only estimates the localizations of sources, but also provides relatively useful and accurate information about the extents of cortical activities.

Objective: The paper aims to understand how the elderly perceive the healthcare services of their aged care facilities. This paper explores different dimensions of servicescape elements, which ultimately affect the development of healthcare services. Design: Both naturalistic observations and in-depth interviews were conducted to discover the perceptions servicesape elements. Results: The authors discovered that servicescape elements rely not only on physical, social and socially symbolic dimensions but also on cultural dimensions. Conclusions: This study uses the elderly home context in City of Harlingen, Rio Grande Valley, Texas, USA, and finds support to Rosenbaum and Massiah [1]’s multidimensional model and suggests improvements in servicescape elements. We found that factors such as ambience, signage, layout, and socially symbolic structure at the aged care facility, were highly appreciated by the elder residents. Other factors such as privacy, quiet environment, and social interactions among patients via group activities require improvements and further attention. Findings of the study can be generalized in other similar social contexts, particularly in improving Asia Pacific region’s healthcare services.

Behavioral assessment of sound localization in the Coma Recovery Scale-Revised (CRS-R) poses a significant challenge due to motor disability in patients with disorders of consciousness (DOC). Brain-computer interfaces (BCIs), which can directly detect brain activities related to external stimuli, may thus provide an approach to assess DOC patients without the need for any physical behavior. In this study, a novel audiovisual BCI system was developed to simulate sound localization evaluation in CRS-R. Specifically, there were two alternatively flashed buttons on the left and right sides of the graphical user interface, one of which was randomly chosen as the target. The auditory stimuli of bell sounds were simultaneously presented by the ipsilateral loudspeaker during the flashing of the target button, which prompted patients to selectively attend to the target button. The recorded electroencephalography data were analyzed in real time to detect event-related potentials evoked by the target and further to determine whether the target was attended to or not. A significant BCI accuracy for a patient implied that he/she had sound localization. Among eighteen patients, eleven and four showed sound localization in the BCI and CRS-R, respectively. Furthermore, all patients showing sound localization in the CRS-R were among those detected by our BCI. The other seven patients who had no sound localization behavior in CRS-R were identified by the BCI assessment, and three of them showed improvements in the second CRS-R assessment after the BCI experiment. Thus, the proposed BCI system is promising for assisting the assessment of sound localization and improving the clinical diagnosis of DOC patients.

In recent years, China's achievements in artificial intelligence (AI) have attracted the attention of the world, and AI technology has penetrated into all walks of life. In particular, the in-depth integration of AI technology with sports education guidance and physical fitness evaluation has achieved very significant progress and results, which has improved the quality of life of people and provided more high-quality, customized, and personalized health management services for human beings. This study aimed to explore the application model of deep learning in sports education and guidance and in the analysis of the residents' physical fitness, so as to formulate a personalized and intelligent exercise program. The residents of A and B units are selected as the research object to evaluate the physical fitness. Subsequently, the self-designed questionnaire is used to survey the chronic disease online, and the acquired data are put into a deep learning model for the analysis to obtain the physique scoring results and exercise guidance. According to the results of physical fitness evaluation, the proportion of overweight was the highest (40.4%), followed by fatty liver (24.3%) and hyperlipidemia (20.4%), showing high incidence in people aged 41–50 years. The highest incidence of female gynecological diseases was gout (23.0%) and hyperlipidemia (20.6%). After exercise therapy, the scores were excellent and good. Conclusions: The database SQL Server 2005 was a platform for storing all kinds of data and knowledge-based rule information. The user's access service was provided by the remote server via the browser. Therefore, building a rule-based reasoning mechanism can realize physical test data collection, physical fitness evaluation, and information management for improving physical fitness.

Research purpose: to analyze farmers’ willingness to gather homestead and its influencing factors, so as to provide decision-making basis for the rational layout of rural homestead. Methods: questionnaire, logistic model. The results are as follows. (1) Farmers’ willingness to gather homesteads is highest in dam areas, followed by hilly areas, and is lowest in mountainous areas. (2) The respondents’ age, family support ratio, housing structure, whether the access road is paved, and the distance from the main road have significant negative impacts on farmers’ willingness to gather homesteads, while homesteads being idle, the service life of the house, the type of daily energy use, and whether they are far from relatives after relocation have significant positive impacts on farmers’ willingness to gather homesteads. (3) The main influencing factors of farmers’ homestead agglomeration in dam areas are the idle situation of a homestead, housing structure, the service life of the house, and whether they are satisfied with their current homestead residence. (4) The main influencing factors of farmers’ homestead agglomeration in hilly areas are the age of the respondents, the proportion of family workers, and whether they accept the relocation and are far from relatives. (5) The main influencing factors of farmers’ homestead agglomeration in mountainous areas are the age of the respondents, the ratio of family support, the housing structure, and whether the access road is paved. We conclude that there are significant differences in farmers’ willingness to gather homesteads and the influencing factors in different geomorphic areas. Policy makers should formulate differentiated homestead agglomeration optimization schemes and design the optimization paths of homestead agglomeration on the basis of geomorphic classification and subregion.

BackgroundUsing task-dependent neuroimaging techniques, recent studies discovered a fraction of patients with disorders of consciousness (DOC) who had no command-following behaviors but showed a clear sign of awareness, which was defined as cognitive motor dissociation (CMD). Although many efforts were made to identify the CMD, existing task-dependent approaches might fail when patients had multiple cognitive function (e.g., attention, memory) impairments, and thus lead to false-negative findings. However, recent advances in resting-state fMRI (rs-fMRI) analysis allow investigation of the dynamic change of spontaneous brain activity, which might be a powerful tool to test the patient’s cognitive functions, while its capacity in identifying CMD was unclear.MethodsThe rs-fMRI study included 119 participants from three independent research sites. A sliding-window approach was used to investigate the dynamic functional connectivity of the brain in two aspects: the global and regional temporal stability, which measures how stable the brain functional architecture is across time. The temporal stability was compared in the first dataset (36/16 DOC/controls), and then a Support Vector Machine (SVM) classifier was built to discriminate DOC patients from controls. Furthermore, the generalizability of the SVM classifier was tested in the second independent dataset (35/21 DOC/controls). Finally, the SVM classifier was applied to the third independent dataset where patients underwent an rs-fMRI and brain-computer interface assessment (4/7 CMD/potential non-CMD), to test its performance in identifying CMD.ResultsOur results showed that the global and regional temporal stability were impaired in DOC patients, especially in regions from the cingulo-opercular task control, default mode, fronto-parietal task control, and salience network. Using the temporal stability as features, the SVM model not only showed a good performance in the first dataset (accuracy = 90 %), but a good generalizability in the second dataset (accuracy = 82 %). Most importantly, the SVM model generalized well in identifying CMD in the third dataset (accuracy = 91 %).ConclusionThe current findings suggested that rs-fMRI could be a potential tool to assist in diagnosing CMD. Furthermore, the temporal stability investigated in this study also contributed to a deeper understanding of the neural mechanism of the consciousness.

Through the more available acoustic information or the polarization information provided, vector sensor arrays outperform the scalar sensor arrays in accuracy of localization. However, the cost of a vector sensor array is higher than that of a scalar sensor array. To reduce the cost of a two-dimensional (2-D) vector sensor array, a hybrid T-shaped sensor array consisting of two orthogonal uniform linear arrays (ULAs) is proposed, where one ULA is composed of acoustic vector sensors and the other is composed of scalar sensors. By utilizing the cross-correlation tensor between the received signals from the two ULAs, two virtual uniform rectangular arrays (URAs) of acoustic vector sensors are obtained, and they can be combined into a larger URA. It is shown that a larger acoustic vector sensor URA with M2+1 degrees of freedom (DOFs) can be obtained from the specially designed T-shaped array with M acoustic vector sensors and 2M scalar sensors. Furthermore, by means of the proposed tensor model for the larger URA, the inter-sensor spacing can be allowed to exceed greatly a half-wavelength. Accordingly, the proposed method can achieve both a high DOF and a large array aperture. Simulation results show that the proposed method has a better performance in 2-D direction-of-arrival estimation than some existing methods under the same array cost.

Background: Atelectasis and attic retraction pocket are two common tympanic membranes changes. However, general practitioners, pediatricians and otolaryngologists showed low diagnostic accuracy for these ear diseases. Therefore, there is a need to develop a deep learning model to detect atelectasis and attic retraction pocket automatically. Method: 6393 OME otoscopic images from 3 centers were used to develop and validate a deep learning model to detect atelectasis and attic retraction pocket. 3-fold random cross validation was adopted to divided dataset into training set and validation set. A team of otologists were assigned to diagnose and label. Receiver operating characteristic (ROC) curve, 3-fold average classification accuracy, sensitivity and specificity were used to assess the performance of deep learning model. Class Activation Mapping (CAM) was applied to show the discriminative region in the otoscopic images. Result: Among all the otoscopic images, 3564 (55.74%) images were identified with attic retraction pocket, and 2460 (38.48%) images were identified with atelectasis. The automatically diagnostic model of attic retraction pocket and atelectasis achieved 3-fold cross validation accuracy of 89% and 79%, AUC of 0.89 and 0.87, sensitivity of 0.93 and 0.71, and specificity of 0.62 and 0.84 respectively. Bigger and deeper atelectasis and attic retraction pocket showed more weight with red color in the heat map of CAM. Conclusion: Deep learning algorithm could be used to identify atelectasis and attic retraction pocket, which could be used as a tool to assist general practitioners, pediatricians and otolaryngologists. Key words: deep learning, otoscopic images, atelectasis, attic retraction pocket

Covert attention aids us in monitoring the environment and optimizing performance in visual tasks. Past behavioral studies have shown that covert attention can enhance spatial resolution. However, electroencephalography (EEG) activity related to neural processing between central and peripheral vision has not been systematically investigated. Here, we conducted an EEG study with 25 subjects who performed covert attentional tasks at different retinal eccentricities ranging from 0.75° to 13.90°, as well as tasks involving overt attention and no attention. EEG signals were recorded with a single stimulus frequency to evoke steady-state visual evoked potentials (SSVEPs) for attention evaluation. We found that the SSVEP response in fixating at the attended location was generally negatively correlated with stimulus eccentricity as characterized by Euclidean distance or horizontal and vertical distance. Moreover, more pronounced characteristics of SSVEP analysis were also acquired in overt attention than in covert attention. Furthermore, offline classification of overt attention, covert attention, and no attention yielded an average accuracy of 91.42%. This work contributes to our understanding of the SSVEP representation of attention in humans and may also lead to brain-computer interfaces (BCIs) that allow people to communicate with choices simply by shifting their attention to them.