10 results
Search Results
2. The Swedish Stroke Self-Efficacy Questionnaire: translation and cross-cultural adaptation.
- Author
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Klockar, Erika, Kylén, Maya, McCarthy, Linnea, Koch, Lena von, Gustavsson, Catharina, Jones, Fiona, and Elf, Marie
- Subjects
CROSS-sectional method ,SELF-efficacy ,CRONBACH'S alpha ,SELF-management (Psychology) ,RESEARCH funding ,RESEARCH methodology evaluation ,QUESTIONNAIRES ,RESEARCH evaluation ,JUDGMENT sampling ,DESCRIPTIVE statistics ,STROKE rehabilitation ,PSYCHOMETRICS ,RESEARCH methodology ,STROKE patients ,DATA analysis software ,EVALUATION - Abstract
Objective: To translate and cross-culturally adapt the Stroke Self-Efficacy Questionnaire (SSEQ) from English to Swedish and to evaluate psychometric properties of the questionnaire. Methods: A cross-sectional study design, where the translation followed a process including initial translation, synthesis, backward translation, expert committee, and pretest. Content validity was assessed using Content validity index (CVI). Psychometric assessments included floor-ceiling effects and internal consistency. Results: Language and cultural congruence were achieved, and content validity index scores were high (0.923-1). The psychometric evaluations provided acceptable outcomes concerning internal consistency, with Cronbach's alpha scores for the total scale (0.902), the activities subscale (0.861) and the self-management subscale (0.818) respectively. Ceiling effects were evident, but no floor effects. Conclusion: This study found the Swedish version of the SSEQ promising as a tool for assessment of self-efficacy in a Swedish stroke care setting, although further psychometric assessments are recommended in future studies. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
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3. Validation of Methotrexate Intolerance Severity Score (MISS) questionnaire to measure methotrexate intolerance among rheumatoid arthritis Egyptian patients.
- Author
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Kabil, Hagar Ahmed Tawfik, Sherif, Nahed Mounir, Elhusseiny, Mona Gamal Eldin, and Nassif, Mary Atef
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PEARSON correlation (Statistics) ,T-test (Statistics) ,QUALITATIVE research ,QUESTIONNAIRES ,RESEARCH methodology evaluation ,RHEUMATOID arthritis ,METHOTREXATE ,FISHER exact test ,LOGISTIC regression analysis ,DESCRIPTIVE statistics ,QUANTITATIVE research ,EGYPTIANS ,RESEARCH methodology ,DATA analysis software ,DRUG tolerance ,EVALUATION - Abstract
Background: Rheumatoid arthritis (RA) is a systemic autoimmune chronic inflammatory disease, causing progressive disability. Methotrexate (MTX) is the gold standard drug treatment for RA. Long-term use of MTX is associated with intolerance including gastrointestinal effects. In addition, anticipatory, associative, and behavioral symptoms such as anxiety and irritability are also observed which are often inadequately managed, leading to discontinuation of treatment. Methotrexate Intolerance Severity Score (MISS) questionnaire designed to measure MTX intolerance. The work aims to validate the MISS questionnaire Arabic version for the detection of MTX intolerance among Egyptian RA patients to halt the progression of the disease. Results: A total of 80 patients were involved in this study. Of those, 67 (83.8%) were females with a mean disease duration of 6.9 ± 6.1 years. Forty-eight patients (60%) were intolerant to MTX and 32 patients (40%) were tolerant. Comparison between the tolerant group (n = 32) to MTX and the intolerant group (n = 48) revealed a statistically significant difference between them regarding the DAS28 score and HAQ score. Behavioral intolerance is the predominant factor that directs MTX intolerance. Conclusion: The MISS questionnaire has a good predictive ability to detect MTX intolerance among Egyptian RA patients. Due to its good reliability, serves as an invaluable tool as it detects anticipatory and associative symptoms. [ABSTRACT FROM AUTHOR]
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- 2024
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4. Exploring patients' experience using PROMs within routine post-discharge follow-up assessment after stroke: a mixed methods approach.
- Author
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Mourits, B.M.P., den Hartog, S.J., de Graaf, J.A., Roozenbeek, B., Post, M.W.M., Visser-Meily, J.M.A., and Scholten, E.W.M.
- Subjects
ACADEMIC medical centers ,QUESTIONNAIRES ,INTERVIEWING ,SCIENTIFIC observation ,DISCHARGE planning ,DESCRIPTIVE statistics ,LONGITUDINAL method ,ISCHEMIC stroke ,PHYSICIAN-patient relations ,RESEARCH methodology ,TELEPHONES ,STROKE patients ,HEALTH outcome assessment ,PSYCHOLOGICAL tests ,BARTHEL Index ,PSYCHOSOCIAL factors ,PATIENTS' attitudes ,PATIENT aftercare ,MEDICAL referrals ,EVALUATION - Abstract
Background: Patient Reported Outcomes Measures (PROMs) are being used increasingly to measure health problems in stroke clinical practice. However, the implementation of these PROMs in routine stroke care is still in its infancy. To understand the value of PROMs used in ischemic stroke care, we explored the patients' experience with PROMs and with the consultation at routine post-discharge follow-up after stroke. Methods: In this prospective mixed methods study, patients with ischemic stroke completed an evaluation questionnaire about the use of PROMs and about their consultation in two Dutch hospitals. Additionally, telephone interviews were held to gain in-depth information about their experience with PROMs. Results: In total, 63 patients completed the evaluation questionnaire of which 10 patients were also interviewed. Most patients (82.2–96.6%) found completing the PROMs to be feasible and relevant. Half the patients (49.2–51.6%) considered the PROMs useful for the consultation and most patients (87.3–96.8%) reported the consultation as a positive experience. Completing the PROMs provided 51.6% of the patients with insight into their stroke-related problems. Almost 75% of the patients found the PROMs useful in giving the healthcare provider greater insight, and 60% reported discussing the PROM results during the consultation. Interviewed patients reported the added value of PROMs, particularly when arranging further care, in gaining a broader insight into the problems, and in ensuring all important topics were discussed during the consultation. Conclusions: Completing PROMs appears to be feasible for patients with stroke attending post-discharge consultation; the vast majority of patients experienced added value for themselves or the healthcare provider. We recommend that healthcare providers discuss the PROM results with their patients to improve the value of PROMs for the patient. This could also improve the willingness to complete PROMs in the future. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Qualitative interviews of patients with COPD and muscle weakness enrolled in a clinical trial evaluating a new anabolic treatment: patient perspectives of disease experience, trial participation and outcome assessments.
- Author
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Tabberer, Maggie, Williamson, Nicola, Tatlock, Sophi, Gater, Adam, Grimes, Rebecca, Akinseye, Chika, Neil, David, Mahon-Smith, Aoife, and Nelsen, Linda
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HORMONES ,HEALTH status indicators ,QUALITATIVE research ,VITAL capacity (Respiration) ,SATISFACTION ,RESEARCH funding ,INTERVIEWING ,FUNCTIONAL status ,WEARABLE technology ,MUSCLE weakness ,EXPERIENCE ,OBSTRUCTIVE lung diseases ,QUALITY of life ,RESEARCH methodology ,FORCED expiratory volume ,DIARY (Literary form) ,HEALTH outcome assessment ,EXIT interviewing ,PATIENTS' attitudes ,EVALUATION - Abstract
Background: Chronic obstructive pulmonary disease (COPD) and muscle weakness can cause impaired physical function, significantly impacting patients' health-related quality of life (HRQoL). Loss of muscle strength is usually assessed through clinical and performance outcome (PerfO) assessments, which consists of tasks performed in a standardized manner, providing evidence of a patient's functional ability. However, evidence documenting the patient experience of COPD and muscle weakness is limited. Methods: This two-stage qualitative study used semi-structured interviews in patients aged 45–80 years with COPD (post-bronchodilator forced expiratory volume in 1s [FEV
1 ]/forced vital capacity ratio < 0.70, and FEV1 % predicted of 30–80%) and muscle weakness. In Stage 1, 30-minute concept elicitation interviews were conducted with participants recruited across three US sites to explore impacts on physical functioning and activities of daily living. In Stage 2, interviews were performed with participants exiting a Phase IIa trial investigating the efficacy of a selective androgen receptor modulator (GSK2881078) on leg strength, whereby PerfOs were used to evaluate strength and physical functioning endpoints. These participants completed either 60-minute in-depth (n = 32) or 15-minute confirmatory (n = 35) interviews exploring trial experience, completion of outcome measures, disease experience and treatment satisfaction. Results: In Stage 1 (n = 20), most participants described their muscles as weak (83.3%). Difficulties with walking (100%) and lifting heavy objects (90%) were reported. In Stage 2, 60-minute interviews, all participants (n = 32) reported a positive trial experience. Most participants reported that the home exercise program was easy to fit into daily life (77.8%), the PROactive daily diary was easy to complete (100%) and wearable sensors were easy to use (65.6%). However, technical issues were reported (71%), and few participants (19.4%) found physical assessments easy to complete. Improvements in muscle strength and functional limitations were reported by most participants. The shorter 15-minute confirmatory interviews (n = 35) supported the in-depth interview results. Conclusion: The qualitative interviews generated in-depth evidence of key concepts relevant to patients with COPD and muscle weakness and support the assessments of patient strength and physical function as outcome measures in this population in future studies. Trial number: GSK Stage 1: 206869; Stage 2: 200182, NCT03359473; Registered December 2, 2017, https://clinicaltrials.gov/ct2/show/NCT03359473. [ABSTRACT FROM AUTHOR]- Published
- 2024
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6. Psychometric evaluation of the near activity visual questionnaire presbyopia (NAVQ-P) and additional patient-reported outcome items.
- Author
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Sims, Joel, Sloesen, Brigitte, Bentley, Sarah, Naujoks, Christel, Arbuckle, Rob, Chiva-Razavi, Sima, Pascoe, Ben, Stochl, Jan, Findley, Amy, O'Brien, Paul, and Wolffsohn, James S.
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VISION disorders ,STATISTICAL sampling ,RESEARCH evaluation ,QUESTIONNAIRES ,PRESBYOPIA ,PSYCHOMETRICS ,RESEARCH methodology ,STATISTICAL reliability ,HEALTH outcome assessment ,FACTOR analysis ,DATA analysis software ,EVALUATION ,DISEASE complications - Abstract
Background: The Near Visual Acuity Questionnaire Presbyopia (NAVQ-P) is a patient-reported outcome (PRO) measure that was developed in a phakic presbyopia population to assess near vision function impacts. The study refined and explored the psychometric properties and score interpretability of the NAVQ-P and additional PRO items assessing near vision correction independence (NVCI), near vision satisfaction (NVS), and near vision correction preference (NVCP). Methods: This was a psychometric validation study conducted using PRO data collected as part of a Phase IIb clinical trial (CUN8R44 A2202) consisting of 235 randomized adults with presbyopia from the US, Japan, Australia, and Canada. Data collected at baseline, week 2, and months 1, 2, and 3 during the 3-month trial treatment period were included in the analyses to assess item (question) properties, NAVQ-P dimensionality and scoring, reliability, validity, and score interpretation. Results: Item responses were distributed across the full response scale for most NAVQ-P and additional PRO items. Confirmatory factor analysis supported the pre-defined unidimensional structure and calculation of a NAVQ-P total score as a measure of near vision function. Item deletion informed by item response distributions, dimensionality analyses, item response theory, and previous qualitative findings, including clinical input, supported retention of 14 NAVQ-P items. The 14-item NAVQ-P total score had excellent internal consistency (α = 0.979) and high test-retest reliability (Intraclass Correlation Coefficients > = 0.898). There was good evidence of construct-related validity for all PROs supported by strong correlations with concurrent measures. Excellent results for known-groups validity and ability to detect change analyses were also demonstrated. Anchor-based and distribution-based methods supported interpretation of scores through generation of group-level and within-individual estimates of meaningful change thresholds. A meaningful within-patient change in the range of 8-15-point improvement on the NAVQ-P total score (score range 0–42) was recommended, including a more specific responder definition of 10-point improvement. Conclusions: The NAVQ-P, NVCI, and NVS are valid and reliable instruments which have the ability to detect change over time. Findings strongly support the use of these measures as outcome assessments in clinical/research studies and in clinical practice in the presbyopia population. [ABSTRACT FROM AUTHOR]
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- 2024
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7. The Role of Descriptive and Non-Specific Outcome-Oriented Praise in Child Self-Esteem: A Multiphase, Multimethod Investigation.
- Author
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Robichaud, Jean-Michel, Grenier, Fanny, Joussemet, Mireille, and Mageau, Geneviève A.
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MENTAL orientation ,SELF-evaluation ,CROSS-sectional method ,PREDICTION models ,MOTHERS ,QUESTIONNAIRES ,PRAISE ,SOCIAL role ,PARENTING ,DESCRIPTIVE statistics ,MULTIVARIATE analysis ,EXPERIMENTAL design ,WORLD health ,RESEARCH methodology ,ANALYSIS of variance ,NATIONAL competency-based educational tests ,COMPARATIVE studies ,MOTHER-child relationship ,SELF-perception ,SOCIAL classes ,EVALUATION ,CHILDREN - Abstract
Praise may have different effects on child self-esteem, depending on its informational and evaluative value. In this multiphase, multimethod investigation, we assessed the interplaying role of two outcome-oriented praises that differed in their informational and evaluative value (i.e., descriptive and non-specific praise) on indicators of child self-esteem. In phase 177 mothers reported on their usage of descriptive and non-specific praise, while their child (M = 10.09 years old) reported on their level of self-esteem. In phase 2, a subsample of 43 children completed an experimental art task during which an experimenter offered either descriptive or non-specific praise. Children then rated their competence at that task. Results from phase 1 showed that mother usage of descriptive and non-specific praise interacted to predict child self-esteem. Specifically, the relation between descriptive praise and child self-esteem was positive (vs. non-significant) when mothers used moderate to high (vs. low) amounts of non-specific praise. Furthermore, the relation between non-specific praise and child self-esteem was negative (vs. non-significant) when mothers used low (vs. moderate to high) levels of descriptive praise. Results from phase 2 showed that differences between descriptive and non-specific praise conditions emerged on child perceived competence for children reporting lower (but not higher) global self-esteem. Specifically, children with lower global self-esteem rated themselves as more competent when given descriptive (rather than non-specific) praise. Results underlie the relevance of including descriptive elements when offering outcome-oriented praise to children. They also advance the field by identifying different ways to offer outcome-oriented praise. Highlights: Compared to non-specific praise, descriptive praise is believed to be more informational. Descriptive praise is positively linked to child self-esteem when mothers combine it with non-specific praise. Non-specific praise is negatively linked to child self-esteem when mothers don't combine it with descriptive praise. Children with lower (vs. higher) global self-esteem respond better (vs. similarly) to descriptive praise, compared to non-specific praise. [ABSTRACT FROM AUTHOR]
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- 2024
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8. The burden of headache disorders in North India: methodology, and validation of a Hindi version of the HARDSHIP questionnaire, for a community-based survey in Delhi and national capital territory region.
- Author
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Duggal, Ashish, Chowdhury, Debashish, Krishnan, Anand, Amarchand, Ritvik, and Steiner, Timothy J.
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HEADACHE diagnosis ,CROSS-sectional method ,RESEARCH funding ,HEADACHE ,TRANSLATIONS ,RESEARCH methodology evaluation ,QUESTIONNAIRES ,STATISTICAL sampling ,DESCRIPTIVE statistics ,SURVEYS ,RESEARCH methodology ,CONFIDENCE intervals ,MIGRAINE ,EVALUATION - Abstract
Background: Knowledge of the prevalence and attributable burden of headache disorders in India is sparse, with only two recent population-based studies from South and East India. These produced conflicting results. A study in North India is needed. We report the methodology of such a study using, and validating, a Hindi translation of the Headache-Attributed Restriction, Disability, Social Handicap, and Impaired Participation (HARDSHIP) questionnaire developed by Lifting The Burden (LTB). Almost half of the Indian population speak Hindi or one of its dialects. Methods: The study adopted LTB's standardized protocol for population-based studies in a cross-sectional survey using multistage random sampling conducted in urban Delhi and a surrounding rural area. Trained interviewers visited households unannounced, randomly selected one adult member from each and applied the Hindi version of HARDSHIP in face-to-face interviews. The most bothersome headache reported by participants was classified algorithmically into headache on ≥ 15 days/month (H15 +), migraine (including definite and probable) or tension-type headache (including definite and probable). These diagnoses were mutually exclusive. All participants diagnosed with H15 + and a 10% subsample of all others were additionally assessed by headache specialists and classified as above. We estimated the sensitivity and specificity of HARDSHIP diagnoses by comparison with the specialists' diagnoses. Results: From 3,040 eligible households, 2,066 participants were interviewed. The participating proportions were 98.3% in rural areas but 52.9% in urban Delhi. In the validation subsample of 291 participants (149 rural, 142 urban), 61 did not report any headache (seven of those assessed by HARDSHIP, eight by headache specialists and 46 by both) [kappa = 0.83; 95% CI: 0.74-0.91]. In the remaining 230 participants who reported headache in the preceding year, sensitivity, specificity and kappa with (95% CI) were 0.73 (0.65-0.79), 0.80 (0.67-0.90) and 0.43 (0.34-0.58) for migraine; 0.71 (0.56-0.83), 0.80 (0.730.85) and 0.43 (0.37-0.62) for TTH and 0.75 (0.47-0.94), 0.93 (0.89-0.96) and 0.46 (0.34-0.58) for H15 + respectively. Conclusion: This study validates the Hindi version of HARDSHIP, finding its performance similar to those of other versions. It can be used to conduct population surveys in other Hindi-speaking regions of India. [ABSTRACT FROM AUTHOR]
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- 2024
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9. Screening for affective dysregulation in school-aged children: relationship with comprehensive measures of affective dysregulation and related mental disorders.
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Treier, A.-K., Döpfner, M., Ravens-Sieberer, U., Görtz-Dorten, A., Boecker, M., Goldbeck, C., Banaschewski, T., Aggensteiner, P.-M., Hanisch, C., Ritschel, A., Kölch, M., Daunke, A., Roessner, V., Kohls, G., Kaman, A., Aggensteiner, Pascal-Maurice, Banaschewski, Tobias, Bernheim, Dorothee, Bienioschek, Stefanie, and Boecker, Maren
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RESEARCH evaluation ,RESEARCH methodology evaluation ,RESEARCH methodology ,MEDICAL screening ,RISK assessment ,AFFECTIVE disorders ,CHILD psychopathology ,QUESTIONNAIRES ,CHILDREN'S health ,QUALITY of life ,RESEARCH funding ,EXTERNALIZING behavior ,EMOTION regulation ,RECEIVER operating characteristic curves ,PARENTS ,INTERNALIZING behavior ,EVALUATION ,CHILDREN - Abstract
Affective dysregulation (AD) is characterized by irritability, severe temper outbursts, anger, and unpredictable mood swings, and is typically classified as a transdiagnostic entity. A reliable and valid measure is needed to adequately identify children at risk of AD. This study sought to validate a parent-rated screening questionnaire, which is part of the comprehensive Diagnostic Tool for Affective Dysregulation in Children (DADYS-Screen), by analyzing relationships with comprehensive measures of AD and related mental disorders in a community sample of children with and without AD. The sample comprised 1114 children aged 8–12 years and their parents. We used clinical, parent, and child ratings for our analyses. Across all raters, the DADYS-Screen showed large correlations with comprehensive measures of AD. As expected, correlations were stronger for measures of externalizing symptoms than for measures of internalizing symptoms. Moreover, we found negative associations with emotion regulation strategies and health-related quality of life. In receiver operating characteristic (ROC) analyses, the DADYS-Screen adequately identified children with AD and provided an optimal cut-off. We conclude that the DADYS-Screen appears to be a reliable and valid measure to identify school-aged children at risk of AD. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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10. The Tardive Dyskinesia Impact Scale (TDIS), a novel patient-reported outcome measure in tardive dyskinesia: development and psychometric validation.
- Author
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Farber, Robert H., Stull, Donald E., Witherspoon, Brooke, Evans, Christopher J., Yonan, Charles, Bron, Morgan, Dhanda, Rahul, Jen, Eric, and Brien, Christopher O.'
- Subjects
EXPERIMENTAL design ,RESEARCH evaluation ,STATISTICAL reliability ,RESEARCH methodology ,RESEARCH methodology evaluation ,MOVEMENT disorders ,HEALTH outcome assessment ,INTERVIEWING ,COGNITION ,PSYCHOMETRICS ,QUALITATIVE research ,MULTITRAIT multimethod techniques ,DESCRIPTIVE statistics ,FACTOR analysis ,RESEARCH funding ,DATA analysis software ,EMOTIONS ,SOCIAL skills ,DISEASE complications ,EVALUATION - Abstract
Background: Tardive dyskinesia (TD), a movement disorder in which patients experience abnormal involuntary movements, can have profound negative impacts on physical, cognitive, and psychosocial functioning. The Abnormal Involuntary Movement Scale (AIMS), a clinician-rated outcome, is considered the gold standard for evaluating treatment efficacy in TD clinical trials. However, it provides little information about the impacts of uncontrolled movements from a patient perspective and can be cumbersome to administer in clinical settings. The Tardive Dyskinesia Impact Scale (TDIS) was developed as a patient-reported outcome measure to fulfill the need for a disease-specific impact assessment in TD. The objective of the present study was to develop and evaluate the psychometric properties of the TDIS to determine whether it is fit-for-purpose to measure TD impact. Methods: Data from qualitative studies and phase 3 trials of a VMAT2 inhibitor for the treatment of TD (KINECT3 and KINECT4) were used to determine the psychometric properties of the TDIS. Qualitative research included concept elicitation and cognitive debriefing interviews with TD patients and their caregivers in order to assess how well the TDIS captured key domains of TD impact. Quantitative analyses to examine the psychometric properties of the TDIS included assessing construct validity (factor structure, known groups, and predictive validity) and responsiveness to change. Results: Qualitative results showed that the TDIS captures the key TD impacts reported by patients and caregivers and that the TDIS was interpreted as intended and relevant to patients' experiences. Quantitative results found evidence of 2 underlying domains of the TDIS: physical and socioemotional (Comparative Fit Index > 0.9). Known groups and predictive validity indicated that, compared with the AIMS, the TDIS captures unique content (correlation between AIMS and TDIS = 0.2–0.28). The TDIS showed responsiveness to change in treatment, with TDIS scores improving over 48 weeks in the 2 phase 3 trials. Conclusions: The TDIS captures relevant information about the impact of TD and is easily administered in a clinician's office or patient's home. It may be used longitudinally to show changes in TD burden over time. The TDIS complements the AIMS; using these assessments together provides a more holistic assessment of TD. Plain English summary: Tardive dyskinesia is a condition where people have uncontrollable movements because of taking certain medications for a long time. It is still poorly understood how these uncontrollable movements affect a person's everyday activities. We created a questionnaire called the Tardive Dyskinesia Impact Scale (TDIS). The TDIS is a questionnaire where people with tardive dyskinesia rate how their symptoms affect daily activities such as speaking and walking. People can also rate how the uncontrollable movements make them feel. We used specific tests called psychometric tests to see if the TDIS measures the correct information and if the information is reliable. Findings from this study show that the TDIS is a good way to measure how a person's uncontrollable movements affect everyday activities. The results also show that when people take medicine to help with their symptoms, their TDIS scores are better. When patients stopped taking the medicine, their symptoms were worse, and their TDIS score was worse. The TDIS can help people explain how their uncontrollable movements affect their daily life. This can then help their doctors understand the person's condition better. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
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