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Simple Summary: In radiotherapy treatment, organs at risk and target volumes are contoured by the clinicians to prepare a dosimetry plan. In retrospective data, these structures are not often standardised to universal names across the patients plans, which is required to enable data mining and analysis. In this paper, a new method was proposed and evaluated to automatically standardise radiotherapy structures names using machine learning algorithms. The proposed approach was deployed over a dataset with 1613 patients collected from Liverpool & Macarthur Cancer Therapy Centres, New South Wales, Australia. It was concluded that machine learning techniques can standardise the dosimetry plan structures, taking into consideration the integration of multiple modalities representing each structure during the training process. In progressing the use of big data in health systems, standardised nomenclature is required to enable data pooling and analyses. In many radiotherapy planning systems and their data archives, target volumes (TV) and organ-at-risk (OAR) structure nomenclature has not been standardised. Machine learning (ML) has been utilised to standardise volumes nomenclature in retrospective datasets. However, only subsets of the structures have been targeted. Within this paper, we proposed a new approach for standardising all the structures nomenclature by using multi-modal artificial neural networks. A cohort consisting of 1613 breast cancer patients treated with radiotherapy was identified from Liverpool & Macarthur Cancer Therapy Centres, NSW, Australia. Four types of volume characteristics were generated to represent each target and OAR volume: textual features, geometric features, dosimetry features, and imaging data. Five datasets were created from the original cohort, the first four represented different subsets of volumes and the last one represented the whole list of volumes. For each dataset, 15 sets of combinations of features were generated to investigate the effect of using different characteristics on the standardisation performance. The best model reported 99.416% classification accuracy over the hold-out sample when used to standardise all the nomenclatures in a breast cancer radiotherapy plan into 21 classes. Our results showed that ML based automation methods can be used for standardising naming conventions in a radiotherapy plan taking into consideration the inclusion of multiple modalities to better represent each volume. [ABSTRACT FROM AUTHOR]

This paper presents and evaluates artificial neural network (ANN) models used for macrocell path-loss prediction. Measurement data obtained by utilizing the IS-95 pilot signal from a commercial code-division multiple-access (CDMA) mobile network in rural Australia are used to train and evaluate the models. A simple neuron model and feed-forward networks with different numbers of hidden layers and neurons are evaluated regarding their training time, prediction accuracy, and generalization properties. Furthermore, different backpropagation training algorithms, such as gradient descent and Levenberg--Marquardt, are evaluated. The artificial neural network inputs are chosen to be distance to base station, parameters easily obtained from terrain path profiles, land usage, and vegetation type and density near the receiving antenna. The path-loss prediction results obtained by using the ANN models are evaluated against different versions of the semi-terrain based propagation model Recommendation ITU-R P.1546 and the Okumura--Hata model. The statistical analysis shows that a non-complex ANN model performs very well compared with traditional propagation models with regard to prediction accuracy, complexity, and prediction time. The average ANN prediction results were 1) maximum error: 22 dB; 2) mean error: 0 dB; and 3) standard deviation: 7 dB. A multilayered feedforward network trained using the standard backpropagation algorithm was compared with a neuron model trained using the Levenberg--Marquardt algorithm. It was found that the training time decreases from 150 000 to 10 iterations, while the prediction accuracy is maintained. [ABSTRACT FROM AUTHOR]