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The 23rd annual Barrels meeting was held on the University of California, San Diego campus and highlighted the latest advances in the whisker-to-barrel pathway and beyond. The annual meeting brought together investigators from a dozen countries to present their data in posters and short talks. The meeting focused on several themes, first the barrel system was used as a model to study the consequences that result from alterations in the normal pattern(s) of development. A second session focused on what happens to whisker information once it leaves the layer IV barrel. A third session addressed issues of coding within the barrel system and a final session highlighted the latest advances in the engineering of transgenic mouse lines. The meeting highlighted the utility of the barrel system to study cortical circuitry in the normal and pathological state. [ABSTRACT FROM AUTHOR]