4 results on '"Yang, Dong"'
Search Results
2. A Study of the Contaminated Sediment Management System in Korea, with Suggestions for Improvement.
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Choi, Jin Young, Kim, Suk Hyun, Won, Eun-Ji, Yang, Dong-Beom, Chung, Chang Soo, Kim, Kyoungrean, Choi, Ki Young, Ra, Kongtae, Kim, Kyung-Tae, Yim, Jee Young, Lim, Chae Woon, and Hong, Gi Hoon
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CONTAMINATED sediments , *COASTAL sediments , *MARINE sediments , *COASTAL zone management , *BEACHES , *PUBLIC officers , *OCEAN - Abstract
Choi, J.Y.; Kim, S.H.; Won, E.-J.; Yang, D.B.; Chung, C.S.; Kim, K.; Choi, K.Y.; Ra, K.; Kim, K.-T.; Yim, J.Y.; Lim, C.W., and Hong, G.H., 2018. A Study of the Contaminated Sediment Management System in Korea, with Suggestions for Improvement. In: Shim, J.-S.; Chun, I., and Lim, H.S. (eds.), Proceedings from the International Coastal Symposium (ICS) 2018 (Busan, Republic of Korea). Journal of Coastal Research, Special Issue No. 85, pp. 1426–1430. Coconut Creek (Florida), ISSN 0749-0208. Coastal sediment management, particularly the remediation and sustainable use of dredged contaminated marine sediments, is a critical issue in Korea as it is around the world. Since 1988, the Korean Ministry of Oceans and Fisheries has been conducting projects to clean up contaminated marine sediments. The objective of this study was to analyze the management of Korea's coastal sediments and investigate how the Contaminated Sediment Management System (CSMS) could be improved, so as to strengthen the sustainability of the clean-up projects. The state of the CSMS was diagnosed and improvements were developed by reviewing relevant research, interviewing field experts, and holding meetings with researchers, specialists, and government officials. These improvements were aimed at 1) developing a sustainable and practical CSMS and 2) strengthening the responsibility of local governments for managing coastal pollution. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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3. Long-Term Outcomes of Infliximab Treatment in 582 Korean Patients with Crohn's Disease: A Hospital-Based Cohort Study.
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Park, Sang, Hwang, Sung, Kwak, Min, Kim, Wan, Lee, Jeong-Mi, Lee, Ho-Su, Yang, Dong-Hoon, Kim, Kyung-Jo, Ye, Byong, Byeon, Jeong-Sik, Myung, Seung-Jae, Yoon, Yong, Yu, Chang, Kim, Jin-Ho, Yang, Suk-Kyun, Park, Sang Hyoung, Hwang, Sung Wook, Kwak, Min Seob, Kim, Wan Soo, and Ye, Byong Duk
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INFLIXIMAB , *INFLAMMATORY bowel disease treatment , *ABDOMINAL surgery , *INFUSION therapy , *DISEASE duration , *GASTROINTESTINAL agents , *ASIANS , *CROHN'S disease , *LONGITUDINAL method , *PROPORTIONAL hazards models , *THERAPEUTICS - Abstract
Background and Aims: To date, no large-scale studies have evaluated long-term outcomes of infliximab (IFX) treatment in Korean patients with Crohn's disease (CD).Methods: We analyzed long-term clinical responses to IFX in 582 Korean CD patients who received scheduled IFX treatments at Asan Medical Center. Clinical responses were defined as maintaining IFX without major abdominal surgery (MAS) or dose intensification.Results: Between February 2002 and July 2015, a total of 11,990 IFX infusions were administered to 582 Korean patients with CD over a median period of 36 months. At the end of follow-up, 316 (54.3 %) were still receiving IFX without MAS (71 patients, 12.2 %) or dose intensification (86 patients, 14.8 %). IFX was stopped in 109 (18.7 %) patients because of a loss of response (48 patients, 8.2 %), adverse events (30 patients, 5.2 %), or patient preferences or problems with reimbursement (31 patients, 5.3 %). The cumulative survival for maintenance of IFX without MAS or dose intensification was 89.0, 75.9, 68.3, and 50.8 % at 1, 2, 3, and 5 years, respectively. Multivariate regression analysis identified older age at the initiation of IFX (≥40 years, P = 0.006) and a longer disease duration (≥3 years, P = 0.020) as independent positive predictors of a poorer response to IFX.Conclusions: The long-term efficacy of IFX in a large, real-life cohort of Korean patients with CD appears to be similar to that in previously published Western studies. Our findings support the early use of IFX to obtain better clinical outcomes. [ABSTRACT FROM AUTHOR]- Published
- 2016
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4. The risk of colorectal cancer in inflammatory bowel disease: a hospital-based cohort study from Korea.
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Lee, Ho-Su, Park, Sang Hyoung, Yang, Suk-Kyun, Ye, Byong Duk, Kim, Ji-Hun, Kim, Seon-Ok, Soh, Jae Seung, Lee, Seohyun, Bae, Jung Ho, Lee, Hyo Jeong, Yang, Dong-Hoon, Kim, Kyung-Jo, Byeon, Jeong-Sik, Myung, Seung-Jae, Yoon, Yong Sik, Yu, Chang Sik, and Kim, Jin-Ho
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COLON cancer risk factors , *INFLAMMATORY bowel diseases , *CROHN'S disease , *ULCERATIVE colitis , *DISEASE incidence - Abstract
Objective. Limited data are available on the incidence and risk factors of colorectal cancer (CRC) in Asian patients with inflammatory bowel disease (IBD). Material and methods. Information on 5212 Korean patients with IBD (2414 with Crohn's disease [CD] and 2798 with ulcerative colitis [UC]) was retrieved from the IBD registry of Asan Medical Center. Data on CRC incidence for the entire Korean population were derived from the Korean Statistical Information Service. Results. During 39,951 person-years of follow-up (17,679 for CD and 22,272 for UC), 30 patients (12 with CD and 18 with UC) developed CRC. The standardized incidence ratio (SIR) of CRC was 6.0 (95% confidence interval [CI], 3.10-10.48) for CD and 1.68 (95% CI, 1.00-2.66) for UC; it was 9.69 (95% CI, 5.01-16.93) for CD with colonic involvement and 4.31 (95% CI, 2.46-7.00) for extensive UC. The SIR was also increased in patients diagnosed with IBD at younger than 30 years old. CRC location was the low rectum in 11 of 12 CD patients (91.7%). The cumulative probability of rectal cancer was higher in CD patients with a perianal fistula than in those without a perianal fistula ( p = 0.02). Conclusions. A high prevalence of perianal fistulas in Korean CD patients may be the cause of the predominance of low rectal cancer in this population and the higher SIR of CRC in Koreans than in Westerners. In contrast, the SIR of CRC in Korean UC patients may be similar to that in Western UC patients. [ABSTRACT FROM AUTHOR]
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- 2015
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