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The aim of this qualitative case study is to examine the phenomenon of female students’ disproportionate representation in senior level Physical Health Education (PHE) classes. The subject for this teacher’s Masters level project arose from the first author’s personal observations while teaching across several schools in British Columbia, Canada. Through semi-structured interviews with self-identified female participants, we explore female subject choice and if, along with possible reasons why, females may avoid participation in senior level (grade 11-12) mixed gender PHE activity courses. This discussion asserts that females mostly make conscious choices to avoid mixed gender courses at the senior level for several key reasons; females feel silenced by their male peers, PHE is not an inclusive environment, and females perceive their male counterparts assert dominance over them in PHE class. This paper continues with a discussion regarding reinforced gendered norms and their effect on perceived barriers to female participation in schools, and concludes with suggestions for how schools and educators might support female students’ participation. [ABSTRACT FROM AUTHOR]

Objective: Although mild cognitive impairment (MCI) is generally considered a risk state for dementia, its prevalence and association with dementia are impacted by the number of tests and cut-points used to assess cognition and define "impairment," and sources of norms. Here, we investigate how these methodological variations impact estimates of incident dementia in adults with bipolar disorder (BD), a vulnerable population with pre-existing cognitive deficits and increased dementia risk. Method: Neuropsychological data from 148 adults with BD and 13,610 healthy controls (HC) were drawn from the National Alzheimer's Coordinating Center. BD participants' scores were standardized against published norms and again using regression-based norms generated from HC within the same catchment area as individual BD patients ("site-specific norms"), varying the number of within-domain tests (one vs. two) and the cut-points (−1 vs. −1.5 SD) used to operationalize MCI. Results: Site-specific norms were more sensitive to incident dementia (88.6%–94.3%) than published norms (74.3%–88.6%), but only when using a "single test" definition of impairment. Specificity (22.1%–74.3%), accuracy (37.8%–68.9%), and positive predictive values (26.1%–38.3%) were overall poor. Applying a "single test" definition of impairment resulted in better negative predictive values using site-specific (92.3%–93.3%) than published norms (83.6%–86.2%), and a substantial increase in relative risk of incident dementia relative to published norms. Conclusions: Neuropsychologists should define "impairment" as scores below −1.0 or −1.5 SD on at least two within-domain measures when using published norms to interpret cognitive performance in adults with BD. [ABSTRACT FROM AUTHOR]

Bilateral diffuse uveal melanocytic proliferation (B-DUMP) is a paraneoplastic disorder that may be seen in patients with a known malignancy but more commonly is seen in those without any history of cancer. It leads to multiple uveal tumors with exudative retinal detachment along with thickening of the choroid and generally carries a poor prognosis. Its etio-pathogenesis is poorly understood but is said to involve factors secreted by the systemic malignancy that lead to proliferation of melanocytes in the uvea. We report the presentation and management of a female with history of treated frontal lobe meningioma who presented with neovascular glaucoma along with B-DUMP and was found to have recurrence of the meningioma on neuro-imaging. Central nervous system meningiomas can cause B-DUMP and management of the malignancy may lead to partial resolution of posterior segment manifestations of B-DUMP. [ABSTRACT FROM AUTHOR]

This self-study addresses the embedded racism experienced by a racialized female professor who taught in the USA during Trump's presidency. The article presents two incidents that reflect the emboldened racist behaviors and actions of teacher education students during the Trump administration. The study is based on the author's experiences as a racialized female faculty member in the Midwest. Using critical pedagogy and critical race theory frameworks, the article argues that racism needs to be dismantled in spaces of teacher education programs that have been deeply impacted by the ultra-right politics of the Trump administration. This article calls attention to endemic racism, particularly as experienced by racialized faculty. The author calls on teacher educators to take action in response to such incidents and in support of racialized faculty. [ABSTRACT FROM AUTHOR]

The pandemic has created a restrictive working system including remote working, and flexible hours for the firms and employees all around the globe, thus transforming into a platform economy may reduce unemployment and enhance job opportunities. Therefore, firms are now trying to identify the ways for enhancing survivability of Sustainable Supply Chains (SSCs). This study has made an effort to develop a framework for enhancing survivability of SSCs to survive in and post-COVID-19 pandemic. This study has utilised Stepwise Weight Assessment Ratio Analysis (SWARA) method for identifying the significant factors for enhancing survivability of SSCs to be focused in pandemic situation. The study revealed that 'Supply Chain Network Viability (SCV)' is the main criterion for managing buyer–supplier relationship and enhancing survivability of SSCs during and post-COVID-19 situation. This study is helpful for firms, suppliers, and other stakeholders to focus on the identified factors for healthier future. [ABSTRACT FROM AUTHOR]

A simple and economical method was developed for the extraction and isolation of pentacyclic triterpenoid lantadene A from the leaves of Lantana camara. The lantadene A displays significant anti-inflammatory and anticancer properties via the inhibition of IKK-mediated NF-κB protein. Therefore, the derivatives of lantadene A were synthesised to further optimise the pharmacophore for anti-inflammatory and anticancer activities. The synthesised compounds were docked into the active site of IKK to find the most potent inhibitor of IKK. Molecular docking studies revealed that 3β,22β-diisobutyl substituted lantadene derivative (10) binds to the IKK protein with the highest affinity. Furthermore, in the in silico ADMET studies, the lead IKK inhibitor (10) was found to be Ames non-toxic, non-carcinogen, and a weak inhibitor of hERG. [ABSTRACT FROM AUTHOR]

Postage stamps are a significant visual text of an issuing state. In 1947, British India was divided into independent states of India and Pakistan. The successive new regimes in both countries got the freedom to design, print, and circulate the official visual iconography through postage stamps as a symbol of sovereignty for its citizens and the world community. This article explores how India and Pakistan visualized the narrative of national identity and discourse on development through postage stamps in the first two decades of their independence. The article does not intend to retell the narrative of the postcolonial nation-building process in the subcontinent. Instead, the objective is to introduce postage stamps as a primary visual resource for exploring the contours of public history of India and Pakistan by arguing that stamps retain its importance as excellent visual archives for postcolonial scholarly analysis in the age of new media. [ABSTRACT FROM AUTHOR]