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Background: Previous studies have suggested that there is an association between air pollutants and circulatory and respiratory diseases; however, relatively few have analyzed the association between air pollutants and outpatient visits based on the mortality, hospitalization rates, etc., especially in areas with relatively good air quality. Therefore, we conducted this study to research the association between air pollutants and outpatient visits in Fuzhou, China., Methods: We used a generalized linear Poisson model to study the association between air pollution and outpatient visits for respiratory and circulatory diseases from 2016 to 2018 in Fuzhou, China., Results: In the single pollutant model, nitrogen dioxide (NO 2 ) had a significant effect. For lag day 0 to lag day 5, the effect decreased with every 10 μg/L increase in NO 2 . The daily maximum 8-h mean ozone (O 3 -8h) and upper respiratory outpatient visits were positively associated during the cold period [lag2, excess risk (ER) (95% confidence interval (CI)): 1.68% (0.44-2.94%)], while O 3 -8h and respiratory disease were positively associated during the warm period [lag5, ER (95% CI): 1.10% (0.11-2.10%) and lag4, ER (95% CI): 1.02% (0.032-2.02%)]. Similarly, particulate matter (PM) with an average aerodynamic diameter of less than 10 μm (PM 10 ) and lower respiratory diseases were positively associated during the warm period [lag0, ER (95% CI): 1.68% (0.44-2.94%)]. When the concentration of O 3 -8h was higher than 100 μg/L, there was a positive effect on circulatory [lag5, ER (95% CI): 2.83% (0.65-5.06%)], respiratory [lag5, ER (95% CI): 2.47% (0.85-4.11%)] and upper respiratory [lag5, ER (95% CI): 3.06% (1.38-4.77%)] outpatient visits. The variation in O 3 -8h changed slightly when we adjusted for other air pollutants, and after adjusting for O 3 -8h, the ERs of the other air pollutants changed slightly. After adjusting for PM with an average aerodynamic diameter of less than 2.5 μm (PM 2.5 ), the ERs of the other air pollutants increased, and after adjusting for NO 2 , the ER of PM decreased., Conclusion: Exposure to ambient NO 2 , O 3 , PM 2.5 and PM 10 was associated with an increase in respiratory and circulatory system-related outpatient visits in Fuzhou, China.