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The 2011 Tohoku-oki tsunami inundated the Joban coastal area in the Odaka region of the city of Minamisoma, up to 2818 m from the shoreline. In this study, the flow characteristics of the tsunami were reconstructed from deposits using the DNN (deep neural network) inverse model, suggesting that the tsunami inundation occurred in the Froude supercritical condition. The DNN inverse model effectively estimated the tsunami flow parameters in the Odaka region, including the maximum inundation distance, flow velocity, maximum flow depth, and sediment concentration. Despite having a few topographical anthropogenic undulations that caused the inundation height to fluctuate greatly, the reconstructed maximum flow depth and flow velocity were reasonable and close to the values reported in the field observations. The reconstructed data around the Odaka region were characterized by an extremely high velocity (12.1 ms-1). This study suggests that the large fluctuation in flow depths on the Joban Coast compared with the stable flow depths in the Sendai Plain can be explained by the inundation in the supercritical flow condition. [ABSTRACT FROM AUTHOR]

The simple suspension method (SSM) involves administering tablets or capsules using a tube after disintegration and suspension in hot water without crushing or opening the capsule. Particularly, for anticancer drugs, it is an excellent method of administration that reduces the risk of exposure during dispensing. In contrast, information on SSM for individual drugs is insufficient. Anticancer drugs present a therapeutic challenge because their information is limited. We investigated whether SSM is possible with 36 anticancer drugs. Furthermore, we examined the pH of the suspension of these drugs, for which no information on SSM is available. We found that suspension was possible for 24 of the 36 drugs. Furthermore, the pH of the suspension was measured, which provided important information when considering dissolution solutions other than hot water. Little changes in the pH were observed before or after passing through the tube. The results of this study may improve medication adherence in patients with cancer experiencing dysphagia.