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Parkinson's disease (PD) is a serious movement disorder that may eventually progress to mild cognitive dysfunction (MCI) and dementia. According to the Parkinson's foundation, one million Americans were diagnosed with PD and almost 10 million individuals suffer from the disease worldwide. An early and precise clinical diagnosis of PD will ensure an early initiation of effective therapeutic treatments, which will potentially slow down the progression of the disease and improve the quality of life for patients and their caregivers. Machine and deep learning are promising technologies that may assist and support clinicians in providing an objective and reliable diagnosis of the disease based upon significant and unique features identified from relevant medical data. In this paper, the author provides a comprehensive review of the artificial intelligence techniques that were recently proposed during the period from 2016 to 2022 for the screening and staging of PD as well as the identification of the biomarkers of the disease based on Electroencephalography (EEG), Magnetic Resonance Imaging (MRI), speech tests, handwriting exams, and sensory data. In addition, the author highlights the current and future trends for PD diagnosis based machine and deep learning and discusses the limitations, challenges, potential future solutions, and recommendations for a reliable application of machine and deep learning for PD detection and screening. [ABSTRACT FROM AUTHOR]

Malaria is predominant in many subtropical nations with little health-monitoring infrastructure. To forecast malaria and condense the disease's impact on the population, time series prediction models are necessary. The conventional technique of detecting malaria disease is for certified technicians to examine blood smears visually for parasite-infected RBC (red blood cells) underneath a microscope. This procedure is ineffective, and the diagnosis depends on the individual performing the test and his/her experience. Automatic image identification systems based on machine learning have previously been used to diagnose malaria blood smears. However, so far, the practical performance has been insufficient. In this paper, we have made a performance analysis of deep learning algorithms in the diagnosis of malaria disease. We have used Neural Network models like CNN, MobileNetV2, and ResNet50 to perform this analysis. The dataset was extracted from the National Institutes of Health (NIH) website and consisted of 27,558 photos, including 13,780 parasitized cell images and 13,778 uninfected cell images. In conclusion, the MobileNetV2 model outperformed by achieving an accuracy rate of 97.06% for better disease detection. Also, other metrics like training and testing loss, precision, recall, fi-score, and ROC curve were calculated to validate the considered models. [ABSTRACT FROM AUTHOR]

Degenerative nerve diseases such as Alzheimer's and Parkinson's diseases have always been a global issue of concern. Approximately 1/6th of the world's population suffers from these disorders, yet there are no definitive solutions to cure these diseases after the symptoms set in. The best way to treat these disorders is to detect them at an earlier stage. Many of these diseases are genetic; this enables machine learning algorithms to give inferences based on the patient's medical records and history. Machine learning algorithms such as deep neural networks are also critical for the early identification of degenerative nerve diseases. The significant applications of machine learning and deep learning in early diagnosis and establishing potential therapies for degenerative nerve diseases have motivated us to work on this review paper. Through this review, we covered various machine learning and deep learning algorithms and their application in the diagnosis of degenerative nerve diseases, such as Alzheimer's disease and Parkinson's disease. Furthermore, we also included the recent advancements in each of these models, which improved their capabilities for classifying degenerative nerve diseases. The limitations of each of these methods are also discussed. In the conclusion, we mention open research challenges and various alternative technologies, such as virtual reality and Big data analytics, which can be useful for the diagnosis of degenerative nerve diseases. [ABSTRACT FROM AUTHOR]

Featured Application: Medical diagnosis and computer-aided diagnosis systems. Breast cancer is one of the most common types of cancer among women. Accurate diagnosis at an early stage can reduce the mortality associated with this disease. Governments and health organizations stress the importance of early detection of breast cancer as it is related to an increase in the number of available treatment options and increased survival. Early detection gives patients the best chance of receiving effective treatment. Different types of images and imaging modalities are used in the detection and diagnosis of breast cancer. One of the imaging types is "infrared thermal" breast imaging, where a screening instrument is used to measure the temperature distribution of breast tissue. Although it has not been used often, compared to mammograms, it showed promising results when used for early detection. It also has many advantages as it is non-invasive, safe, painless, and inexpensive. The literature has indicated that the use of thermal images with deep neural networks improves the accuracy of early diagnosis of breast malformation. Therefore, in this paper, we aim to investigate to what extent convolutional neural networks (CNNs) with attention mechanisms (AMs) can provide satisfactory detection results in thermal breast cancer images. We present a model for breast cancer detection based on deep neural networks with AMs using thermal images from the Database for Research Mastology with Infrared Image (DMR-IR). The model will be evaluated in terms of accuracy, sensitivity and specificity, and will be compared against state-of-the-art breast cancer detection methods. The AMs with the CNN model achieved encouraging test accuracy rates of 99.46%, 99.37%, and 99.30% on the breast thermal dataset. The test accuracy of CNNs without AMs was 92.32%, whereas CNNs with AMs achieved an improvement in accuracy of 7%. Moreover, the proposed models outperformed previous models that were reviewed in the literature. [ABSTRACT FROM AUTHOR]

Background: Machine learning (ML) is a key component of artificial intelligence (AI). The terms machine learning, artificial intelligence, and deep learning are erroneously used interchangeably as they appear as monolithic nebulous entities. This technology offers immense possibilities and opportunities to advance diagnostics in the field of medicine and dentistry. This necessitates a deep understanding of AI and its essential components, such as machine learning (ML), artificial neural networks (ANN), and deep learning (DP). Aim: This review aims to enlighten clinicians regarding AI and its applications in the diagnosis of oral diseases, along with the prospects and challenges involved. Review results: AI has been used in the diagnosis of various oral diseases, such as dental caries, maxillary sinus diseases, periodontal diseases, salivary gland diseases, TMJ disorders, and oral cancer through clinical data and diagnostic images. Larger data sets would enable AI to predict the occurrence of precancerous conditions. They can aid in population-wide surveillance and decide on referrals to specialists. AI can efficiently detect microfeatures beyond the human eye and augment its predictive power in critical diagnosis. Conclusion: Although studies have recognized the benefit of AI, the use of artificial intelligence and machine learning has not been integrated into routine dentistry. AI is still in the research phase. The coming decade will see immense changes in diagnosis and healthcare built on the back of this research. Clinical significance: This paper reviews the various applications of AI in dentistry and illuminates the shortcomings faced while dealing with AI research and suggests ways to tackle them. Overcoming these pitfalls will aid in integrating AI seamlessly into dentistry. [ABSTRACT FROM AUTHOR]

Globally, there is a substantial unmet need to diagnose various diseases effectively. The complexity of the different disease mechanisms and underlying symptoms of the patient population presents massive challenges in developing the early diagnosis tool and effective treatment. Machine learning (ML), an area of artificial intelligence (AI), enables researchers, physicians, and patients to solve some of these issues. Based on relevant research, this review explains how machine learning (ML) is being used to help in the early identification of numerous diseases. Initially, a bibliometric analysis of the publication is carried out using data from the Scopus and Web of Science (WOS) databases. The bibliometric study of 1216 publications was undertaken to determine the most prolific authors, nations, organizations, and most cited articles. The review then summarizes the most recent trends and approaches in machine-learning-based disease diagnosis (MLBDD), considering the following factors: algorithm, disease types, data type, application, and evaluation metrics. Finally, in this paper, we highlight key results and provides insight into future trends and opportunities in the MLBDD area. [ABSTRACT FROM AUTHOR]

Simple Summary: Early detection of malignant melanoma (MM) has the potential to significantly reduce morbidity and mortality as the thickness of the lesion is closely associated with prognosis. Artificial intelligence (AI) is a non-invasive technology that has the potential to aid clinicians in the early diagnosis of skin cancers, including melanoma. Performance metrics of machine-based AI have been shown to rival or improve upon clinician diagnosis. However, many studies have limited this scope to pre-build image databases that may not replicate real-world settings experienced in general practice. This systematic review aimed to report the performance of commercial or market-approved dermatoscopic systems with AI in the form of convolutional neural networks (CNNs) when tasked with classifying melanoma. The sensitivity and specificity of CNNs are highly varied and illustrate the necessity of clinician-to-patient interaction in the diagnosis process. Clinicians working in unison with AI show the most promise for better performance when classifying MM. Background: Cutaneous melanoma remains an increasing global public health burden, particularly in fair-skinned populations. Advancing technologies, particularly artificial intelligence (AI), may provide an additional tool for clinicians to help detect malignancies with a more accurate success rate. This systematic review aimed to report the performance metrics of commercially available convolutional neural networks (CNNs) tasked with detecting MM. Methods: A systematic literature search was performed using CINAHL, Medline, Scopus, ScienceDirect and Web of Science databases. Results: A total of 16 articles reporting MM were included in this review. The combined number of melanomas detected was 1160, and non-melanoma lesions were 33,010. The performance of market-approved technology and clinician performance for classifying melanoma was highly heterogeneous, with sensitivity ranging from 16.4 to 100.0%, specificity between 40.0 and 98.3% and accuracy between 44.0 and 92.0%. Less heterogeneity was observed when clinicians worked in unison with AI, with sensitivity ranging between 83.3 and 100.0%, specificity between 83.7 and 87.3%, and accuracy between 86.4 and 86.9%. Conclusion: Instead of focusing on the performance of AI versus clinicians for classifying melanoma, more consistent performance has been obtained when clinicians' work is supported by AI, facilitating management decisions and improving health outcomes. [ABSTRACT FROM AUTHOR]

Chassis system components such as dampers have a significant impact on vehicle stability, driving safety, and driving comfort. Therefore, monitoring and diagnosing the defects of these components is necessary. Currently, this task is based on the driver's perception of component defects in series production vehicles, even though model-based approaches in the literature exist. As we observe an increased availability of data in modern vehicles and advances in the field of deep learning, this paper deals with the analysis of the performance of Convolutional Neural Networks (CNN) for the diagnosis of automotive damper defects. To ensure a broad applicability of the generated diagnosis system, only signals of a classic Electronic Stability Control (ESC) system, such as wheel speeds, longitudinal and lateral vehicle acceleration, and yaw rate, were used. A structured analysis of data pre-processing and CNN configuration parameters were investigated in terms of the defect detection result. The results show that simple Fast Fourier Transformation (FFT) pre-processing and configuration parameters resulting in small networks are sufficient for a high defect detection rate. [ABSTRACT FROM AUTHOR]

Heart disease is a significant public health problem, and early detection is crucial for effective treatment and management. Conventional and noninvasive techniques are cumbersome, time-consuming, inconvenient, expensive, and unsuitable for frequent measurement or diagnosis. With the advance of artificial intelligence (AI), new invasive techniques emerging in research are detecting heart conditions using machine learning (ML) and deep learning (DL). Machine learning models have been used with the publicly available dataset from the internet about heart health; in contrast, deep learning techniques have recently been applied to analyze electrocardiograms (ECG) or similar vital data to detect heart diseases. Significant limitations of these datasets are their small size regarding the number of patients and features and the fact that many are imbalanced datasets. Furthermore, the trained models must be more reliable and accurate in medical settings. This study proposes a hybrid one-dimensional convolutional neural network (1D CNN), which uses a large dataset accumulated from online survey data and selected features using feature selection algorithms. The 1D CNN proved to show better accuracy compared to contemporary machine learning algorithms and artificial neural networks. The non-coronary heart disease (no-CHD) and CHD validation data showed an accuracy of 80.1% and 76.9%, respectively. The model was compared with an artificial neural network, random forest, AdaBoost, and a support vector machine. Overall, 1D CNN proved to show better performance in terms of accuracy, false negative rates, and false positive rates. Similar strategies were applied for four more heart conditions, and the analysis proved that using the hybrid 1D CNN produced better accuracy. [ABSTRACT FROM AUTHOR]

Artificial intelligence is highly regarded as the most promising future technology that will have a great impact on healthcare across all specialties. Its subsets, machine learning, deep learning, and artificial neural networks, are able to automatically learn from massive amounts of data and can improve the prediction algorithms to enhance their performance. This area is still under development, but the latest evidence shows great potential in the diagnosis, prognosis, and treatment of urological diseases, including bladder cancer, which are currently using old prediction tools and historical nomograms. This review focuses on highly significant and comprehensive literature evidence of artificial intelligence in the management of bladder cancer and investigates the near introduction in clinical practice. [ABSTRACT FROM AUTHOR]

Large-scale datasets, which have sufficient and identical quantities of data in each class, are the main factor in the success of deep-learning-based classification models for vision tasks. A shortage of sufficient data and interclass imbalanced data distribution, which often arise in the medical domain, cause modern deep neural networks to suffer greatly from imbalanced learning and overfitting. A diagnostic model of diabetic retinopathy (DR) that is trained from such a dataset using supervised learning is severely biased toward the majority class. To enhance the efficiency of imbalanced learning, the proposal of this study is to leverage retinal fundus images without human annotations by self-supervised or semi-supervised learning. The proposed approach to DR detection is to add an auxiliary procedure to the target task that identifies DR using supervised learning. The added process uses unlabeled data to pre-train the model that first learns features from data using self-supervised or semi-supervised learning, and then the pre-trained model is transferred with the learned parameter to the target model. This wrapper algorithm of learning from unlabeled data can help the model gain more information from samples in the minority class, thereby improving imbalanced learning to some extent. Comprehensive experiments demonstrate that the model trained with the proposed method outperformed the one trained with only the supervised learning baseline utilizing the same data, with an accuracy improvement of 4~5%. To further examine the method proposed in this study, a comparison is conducted, and our results show that the proposed method also performs much better than some state-of-the-art methods. In the case of EyePaCS, for example, the proposed method outperforms the customized CNN model by 9%. Through experiments, we further find that the models trained with a smaller but balanced dataset are not worse than those trained with a larger but imbalanced dataset. Therefore, our study reveals that utilizing unlabeled data can avoid the expensive cost of collecting and labeling large-scale medical datasets. [ABSTRACT FROM AUTHOR]

Epilepsy is a common neurological condition. The effects of epilepsy are not restricted to seizures alone. They comprise a wide spectrum of problems that might impair and reduce quality of life. Even with medication, 30% of epilepsy patients still have recurring seizures. An epileptic seizure is caused by significant neuronal electrical activity, which affects brain activity. EEG shows these changes as high-amplitude spiky and sluggish waves. Recognizing seizures on an electroencephalogram (EEG) manually by a professional neurologist is a time-consuming and labor-intensive process, hence an efficient automated approach is necessary for the identification of epileptic seizure. One technique to increase the speed and accuracy with which a diagnosis of epileptic seizures could be made is by utilizing computer-aided diagnosis systems that are built on deep neural networks, or DNN. This study introduces a fusion of recurrent neural networks (RNNs) and bi-directional long short-term memories (BiLSTMs) for automatic epileptic seizure identification via EEG signal processing in order to tackle the aforementioned informational challenges. An electroencephalogram's (EEG) raw data were first normalized after undergoing pre-processing. A RNN model was fed the normalized EEG sequence data and trained to accurately extract features from the data. Afterwards, the features were passed to the BiLSTM layers for processing so that further temporal information could be retrieved. In addition, the proposed RNN-BiLSTM model was tested in an experimental setting using the freely accessible UCI epileptic seizure dataset. Experimental findings of the suggested model have achieved avg values of 98.90%, 98.50%, 98. 20%, and 98.60%, respectively, for accuracy, sensitivity, precision, and specificity. To further verify the new model's efficacy, it is compared to other models, such as the RNN-LSTM and the RNN-GRU learning models, and is shown to have improved the same metrics by 1.8%, 1.69%, 1.95%, and 2.2% on using 5-fold. Additionally, the proposed method was compared to state-of-the-art approaches and proved to be a more accurate categorization of such techniques. [ABSTRACT FROM AUTHOR]