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A new cadmium (II) complex, [Cd(4-Me-5-CHOIm)Cl] has been synthesized and characterized using single crystal X-ray diffraction study. The interaction of the complex with calf thymus DNA (CT-DNA) and double stranded RNA [polyinosinic·polycytidylic acid (poly(I)·poly(C)] has been investigated by various biophysical techniques. The interaction of the complex with CT-DNA and RNA displays a binding order of 10. Graphical Abstract: A new cadmium (II) coordination polymer, [Cd(4-Me-5-CHOIm)Cl] has been synthesized. The binding of the complex with double stranded DNA, RNA has been carried out by different spectroscopic techniques and energetic of the interaction was derived from isothermal titration calorimetry (ITC). [ABSTRACT FROM AUTHOR]

The ligand 3,3-( p-phenylenedimethylene) bis{1-(2-methylallyl)} imidazolium bromide ( 1) and its Palladium(II) N-heterocyclic carbene (NHC) complex ( 3) has been synthesized and characterized by several spectroscopic techniques and the solid-state structure of 3 has been determined by single crystal X-ray diffraction studies. The Pd(II) complex possesses ring head to tail π- π stacking interactions (3.767 A ) through imidazole rings. Complex 3 catalyzes Suzuki-Miyaura 'C-C' coupling reaction. DFT calculations have been used to understand the HOMO/LUMO energy and hence the stability and reactivity of Pd(II) complex in syn and anti-configuration. [Figure not available: see fulltext. Caption: Palladium(II) N-heterocyclic carbene (NHC) complex ( 3) of the ligand 3,3'-(pphenylenedimethylene) bis{1-(2-methylallyl)}imidazolium bromide has been synthesized and characterized by several spectroscopic techniques and finally the solid-state structure of 3 has been determined by single-crystal X-ray diffraction studies. The Pd(II) complex possesses ring head to tail Π-Π stacking interaction (3.767 Ǻ) through imidazole rings. Complex 3 catalyzes Suzuki-Miyaura 'C-C' coupling reaction. DFT calculations were performed to know HOMO/LUMO energy and hence the stability and reactivity of Pd(II) complex in syn- and anti-configuration.] [ABSTRACT FROM AUTHOR]

A terpyridine based compound L1 was designed and synthesized as an “off–on” chemosensor for the detection of Zn2+. Chemosensor L1 showed excellent selectivity and sensitivity toward Zn2+ by exhibiting a large fluorescence enhancement (∼51-fold) at 370 nm whereas other competitive metal ions did not show any noticeable change in the emission spectra of chemosensor L1. The chemosensor (L1) was shown to detect Zn2+ ions down to 9.76 μM at pH 7.4. However, chemosensor L1 binds Zn2+ in a 1 : 2 ratio (receptor : metal) with an association constant of 1.85 × 104 (R2 = 0.993) and this 1 : 2 stoichiometric fashion is established on the basis of a Job plot and mass spectroscopy. DFT/TD-DFT calculations were carried out to understand the binding nature, coordination features and electronic properties of L1 and the L1–2Zn2+ complex. In addition, this “turn-on” fluorescence probe was effectively used to image intracellular Zn2+ ions in cultured MDA-MB-468 cells. [ABSTRACT FROM AUTHOR]