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Background Less than half of migraineurs receive prescription treatment and this causes a great loss of economical resources. We aimed to evaluate the effect of migraine treatment on migraine-related economic burden among migraineurs employed in schools. Methods Forty-two subjects with migraine with two or more attacks per month included in this study. The first three-month phase was screening phase, followed by "medication adjustment phase" and the "treatment phase". Subjects prescribed symptomatic treatment only or preventive and symptomatic treatment. All subjects kept the records of the frequency, intensity and duration of headaches, number of days missed from work, decreased productivity at work, number of acute medication intake and referral to the emergency department during an attack. Results Frequency, severity and duration of headache, monthly headache days, analgesic intake per month, number of days with producvtivity loss were found to be significantly lower during treatment phase than screening phase (p<0.05). Impact of treatment started on the fourth and fifth months of the study. Direct cost in the treatment phase was significantly higher compared to the screening phase (p<0.05). Conclusion Our study results showed that migraine treatment significantly decreased indirect cost of migraine. Maximum effort should be made by the headache societies in order to increase the treatment rates of migraine sufferers. [ABSTRACT FROM AUTHOR]

Objectives: To investigate the factors influencing progression and chronification of episodic migraine, we conducted a 12-month face to face follow-up study of episodic migraine patients. Methods: One hundred eighty patients with episodic migraine were enrolled. 120 parameters were analyzed including demographic factors, social and life-style features, comorbid medical illnesses and headache characteristics. After the first evaluation, all patients was scheduled to a structured face to face interview at 3-months interval for one-year. Results: Thirty-two (17,7%) patients developed chronic daily headache. Four out of 32 (2,2%) had definite chronic migraine. Low education level, obesity, greater tea consumption (≥4 cups/daily), predominantly hot and spicy diet, high headache frequency, long duration of headache and presence of allodynia at baseline, and more days with symptomatic drug intake were significant risk factors for progression and chronification of migraine. Cox regression analysis revealed triptan and NSAID intake, hot and spicy eating habit and allodynia as risk factors for chronification. Conclusion: Higher amount of tea consumption, hot and spicy diet appeared to be new risk factors for chronification of migraine. Weight gain is one of the most important risk factors. Patients should be warned about the risk factors to prevent chronification. [ABSTRACT FROM AUTHOR]