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Copyright of Compendium of Veterinary Sciences / Compendio de Ciencias Veterinarias is the property of Facultad de Ciencias Veterinarias de la Universidad Nacional de Asuncion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Compendium of Veterinary Sciences / Compendio de Ciencias Veterinarias is the property of Facultad de Ciencias Veterinarias de la Universidad Nacional de Asuncion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

La salmonelosis es una enfermedad bacteriana cuyo agente causal es del género Salmonella, el cual está conformado por dos especies principales: Salmonella (S) enterica y S. bongori. La mayoría de los serovares de Salmonella entérica que afectan al hombre y/o animal, generalmente causan patologías gastrointestinales en una amplia variedad de huéspedes. Es importante recalcar que un reducido número de serovares es capaz de adaptarse a una estrecha escala de especies huésped (S. Gallinarum., S. Pullorum). En este contexto, la Tifus Aviar, es una enfermedad bacteriana septicémica, de evolución aguda o crónica, sin distinción etaria, siendo las adultas las más susceptibles; considerada una amenaza importante para la industria avícola porque repercute negativamente en la rentabilidad de la producción. El objetivo de este trabajo es describir los hallazgos anatomopatológicos observados en cinco aves de donde se aisló S. Gallinarum intralesionalmente. Se realizó la necropsia de cinco aves, donde se recolectaron muestras de las lesiones para histopatología y microbiología. Microscópicamente, se evidenció plumas apelmazadas en la cloaca por abundante diarrea amarilla pálida a verdosa, con estrías blancas. Atrofia de los músculos pectorales. Se observó en el hígado un color rojo pálido a bronce, aumentado, con dos focos blanco-amarillentos, firmes, sobresalientes en la mayoría, de 1cm y 1mm de diámetro. Bazo aumentado. Intestino delgado con petequias multifocales en mucosa. Los riñones de color rojo pálido, friables y aumentados. Los folículos ováricos en diversos estadios de diferenciación rojo brillante. Microscópicamente los hepatocitos presentan diferentes grados de degeneración vacuolar (hidrópica y esteatosis), en algunos casos con una gran vacuola intracitoplasmática que desplaza al núcleo excéntricamente. Además, se evidencia necrosis focal. Las sinusoides se encuentran dilatados con marginación de heterófilos; en el espacio de Disse y periportal se observan múltiples focos de linfocitos y heterófilos. Con amplias zonas focales de necrosis de tipo microgranulomatosa. Los diagnósticos anatomopatológicos fueron: Hepato- y esplenomegalia, nefromegalia, duodenitis catarral severa asociada con micro)úlceras de distribución multifocal. El cultivo y aislamiento microbiológico reportó SGallinarum. Las lesiones son compatibles con Tifus aviar y el aislamiento del agente causal confirma la enfermedad. Es importante el aislamiento para el diagnóstico de la enfermedad debido a que las lesiones anatomopatológicas observadas deben ser diferenciadas de otras enfermedades como histiomoniasis; pullorosis y cólera aviar. [ABSTRACT FROM AUTHOR]

Copyright of Compendium of Veterinary Sciences / Compendio de Ciencias Veterinarias is the property of Facultad de Ciencias Veterinarias de la Universidad Nacional de Asuncion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Compendium of Veterinary Sciences / Compendio de Ciencias Veterinarias is the property of Facultad de Ciencias Veterinarias de la Universidad Nacional de Asuncion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Compendium of Veterinary Sciences / Compendio de Ciencias Veterinarias is the property of Facultad de Ciencias Veterinarias de la Universidad Nacional de Asuncion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Compendium of Veterinary Sciences / Compendio de Ciencias Veterinarias is the property of Facultad de Ciencias Veterinarias de la Universidad Nacional de Asuncion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Las neoplasias hepáticas pueden surgir de elementos epiteliales, hepatocitos y epitelio biliar de conductos biliares. El hígado es sitio común para formación de tumores malignos; la mayoría son metástasis de otros órganos. Las neoplasias primarias más frecuentes son el carcinoma hepatocelular y el colangiocarcinoma. El objetivo del trabajo es describir los hallazgos anatomopatológicos de masas intrahepáticas en un gato. Un gato de siete años, común europeo, que presentó pérdida de peso, asociado a disminución del apetito y finalmente anorexia; con marcadores bioquímicos renales por arriba del rango de referencia normal; fue necropsiado para la recolección de muestras y estudio histopatológico de rutina. En el examen post-mortem se determinó condición corporal regular (2/4); ojos hundidos y piel con pérdida de elasticidad. Todos los lóbulos hepáticos presentaron masas sobresalientes, blancas, coalescentes con diámetro de 0,1 a 7,5 cm, tensoelásticas a friables y con aspecto de botón con centro deprimido las masas más grandes. Además, el 95% del órgano estaba afectado. Superficie de corte con zonas sobreelevadas, aspecto lobular en mosaico con colores desde blanco, gris, amarillo-verdoso, rojo a negro. Áreas blancas irregulares coalescentes. Bordes hepáticos cortantes y vías biliares extrahepáticas sin particularidad. Riñones amarillos, derecho con 10 cm² y 2,8 cm de diámetro e izquierdo con 6,8 cm² y 1,9 cm de diámetro; este último con múltiples masas blancas sobresalientes de 0,1 a 0,5 cm de diámetro, superficie de corte con infiltración hasta la corteza. Relación médula: corteza disminuida y con congestión corticomedular. Microscópicamente las masas intrahepáticas están bien delimitadas y comprimen el parénquima; están conformadas por hepatocitos dispuestos en forma acinar, de núcleo redondo, cromatina laxa a reticular, eventuales nucléolos. Citoplasma eosinófilo claro. Además, se identifica megahepatocitos algunos con vacuolizaciones variables; células multinucleadas e índice mitótico moderado. Resto del parénquima hepático con cordones de hepatocitos distorsionados, sinusoides dilatados y hemorragias. Espacio porta con infiltrado mononuclear difuso. Los riñones presentan una nefritis intersticial severa difusa mononuclear con células neoplásicas. Las masas intrahepáticas corresponden a un Carcinoma Hepatocelular tipo Adenoide con metástasis en riñón izquierdo; por el grado de diferenciación moderado y disposición acinar no correspondería a un carcinoma hepatoceular tubular y/o sólido. Además, solo se evidencia comprometimiento de hepatocitos y no de vías biliares intrahepáticas por lo que se descarta colangiocarcinoma. [ABSTRACT FROM AUTHOR]

Multisystemic granulomatous lesions are the most common finding in ferrets infected by ferret systemic coronavirus (FRSCV). To characterize the inflammatory response developed against this virus, lesions from 4 naturally infected ferrets were examined. Lesions were classified into the 4 known types of granulomas (granulomas without necrosis [G], granulomas with necrosis [G-N], granulomas with neutrophils [G-NL], and diffuse granulomatous inflammation [DG]). The cellular composition of the lesions was characterized on the basis of cellular morphology and immunohistochemistry using markers for T and B-lymphocytes, plasma cells, macrophages, and neutrophils. The extent and distribution of viral antigen expression was also assessed. In G lesions, macrophages were mainly located in the center of the granuloma, with a moderate number of T-lymphocytes scattered among the macrophages, plasma cells, and B-lymphocytes. G-N lesions exhibited a necrotic center surrounded by abundant macrophages, some T-lymphocytes, plasma cells, and a few B-lymphocytes. In G-NL lesions, there was a central area dominated by neutrophils with low numbers of macrophages, plasma cells, and lymphocytes. DG presented similar cell proportions, but distributed evenly throughout the lesions. FRSCV was expressed in G, G-NL, G-N, and DG, with decreasing numbers of immunoreactive cells. This study reveals the important role of macrophages in the inflammatory response of ferrets against the virus and the variable proportions of leukocytes among different types of lesions, indicating their variable age. The results also confirm the similarities of the disease in ferrets to feline infectious peritonitis. [ABSTRACT FROM AUTHOR]

Copyright of Compendium of Veterinary Sciences / Compendio de Ciencias Veterinarias is the property of Facultad de Ciencias Veterinarias de la Universidad Nacional de Asuncion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Compendium of Veterinary Sciences / Compendio de Ciencias Veterinarias is the property of Facultad de Ciencias Veterinarias de la Universidad Nacional de Asuncion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A 2-year-old female boxer dog was presented with a vaginal serosanguineous discharge not associated with oestrus. There was a friable mass occupying the upper caudal part of the vagina. Cytological and histological examination revealed a monomorphic population of neoplastic round cells consistent with canine transmissible venereal tumour (TVT). In addition, Leishmania spp. amastigotes were found within the neoplastic tissue. In order to characterize whether the amastigotes were present inside macrophages and/or neoplastic cells, a co-localization study using cell- and pathogen-specific markers was performed. To detect Leishmania spp. a 5.8S ribosomal RNA (rRNA) parasite-specific sequence was used for in-situ hybridization and Mac387 was used as a macrophage marker for immunohistochemistry. Leishmania spp. rRNA was detected inside Mac387(+) macrophages and within the cytoplasm of some neoplastic cells. DNA isolation and polymerase chain reaction using specific primers and sequencing analysis identified the organism as Leishmania infantum (syn. Leishmania chagasi). This is the first report describing infection of tumour cells by L. infantum in a genital TVT from an asymptomatic bitch. Transplantation of Leishmania-laden neoplastic cells could represent an alternative route of venereal transmission of leishmaniasis among dogs., (Copyright © 2012 Elsevier Ltd. All rights reserved.)