1. Long-term impact of COVID-19 among maintenance haemodialysis patients.
- Author
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Chawki S, Buchard A, Sakhi H, Dardim K, El Sakhawi K, Chawki M, Boulanger H, Kofman T, Dahmane D, Rieu P, Attaf D, Ahriz-Saksi S, Masoumi A, Diddaoui AZ, Fromentin L, Michaut P, Nebbad R, Desassis JF, Nicolet L, Sohier-Attias J, Besson F, Boula R, Hafi A, Ghazali A, Lamriben L, Arezki A, Dupuis E, Rifard MK, Joly D, Attias P, and El Karoui K
- Abstract
Background: Maintenance haemodialysis (MHD) patients have a high risk of initial mortality from coronavirus disease 2019 (COVID-19). However, long-term consequences of this disease in the MHD population are poorly described. We report the clinical presentation, outcome and long-term follow-up of MHD patients affected by COVID-19 in a multicentric cohort from the Paris, France area., Methods: We conducted a retrospective analysis of clinical presentation and long-term follow-up of MHD patients affected by COVID-19 in 19 MHD centres in the Paris, France area., Results: In this cohort of 248 patients with an initial mortality rate of 18%, age, comorbidities, dyspnoea and previous immunosuppressive treatment were associated with death at <30 days. Among the 203 surviving patients following the acute phase, long-term follow-up (median 180 days) was available for 189 (93%) patients. Major adverse events occurred in 30 (16%) patients during follow-up, including 12 deaths (6%) after a median of 78 days from onset of symptoms. Overall, cardiovascular events, infections and gastrointestinal bleeding were the main major adverse events. Post-COVID-19 cachexia was observed in 25/189 (13%) patients. Lower initial albuminaemia was significantly associated with this cachexia. No reinfection with severe acute respiratory syndrome coronavirus 2 was observed., Conclusions: This work demonstrates the long-term consequences of COVID-19 in MHD patients, highlighting both initial and long-term severity of the disease, including severe cachexia., (© The Author(s) 2021. Published by Oxford University Press on behalf of the ERA.)
- Published
- 2021
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