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AbstractObjectiveMethodsResultsConclusionTo analyze the effectiveness of stent retriever mechanical thrombectomy combined with tirofiban in treating acute ischemic stroke.Markedly effective is defined as an SIS score of over 90, effective is indicated by an SIS score of between 50–90, and a score of below 50 suggests ineffective treatment results.①The treatment’s overall effectiveness in the observation group (91.30%) was significantly higher than that in the control group (75.56%) (p < 0.05). ②The vascular recanalization rate in the observation group (89.13%) was significantly higher than that in the control group (71.11%) (p < 0.05). ③The stent retrieval operation count (2.41 ± 0.23) was significantly lower in the observation group than in the control group (1.29 ± 0.16) (p < 0.05). ④ After treatment, the platelet aggregation rate (10.74 ± 3.95) and NIHSS scores (6.58 ± 1.04) were significantly lower, and the Barthel index (77.86 ± 7.21) was significantly higher in the observation group compared to the control group (26.47 ± 5.12, 7.75 ± 2.36, 68.12 ± 6.15) (p < 0.05). All platelet aggregation rate, NIHSS scores and Barthel Index showed significant improvement after treatment when compared to those before treatment (p < 0.05).The combined application of stent retriever mechanical thrombectomy and tirofiban in acute ischemic stroke treatment shows promising effectiveness. Compared to stent retriever alone, tirofiban adjunctive therapy enhances vascular recanalization, reduces retrieval procedures, shortens treatment duration, inhibits platelet aggregation, and improves neurological function recovery, daily living activities, and prognosis. Moreover, it doesn’t significantly increase symptom-related risks. [ABSTRACT FROM AUTHOR]

Using the CH3OH molecular energy levels data base management program, we deduced that when a CH3OH laser pumped by CO2-9P(16) line, there should be a FIR laser line of 918μm wavelength, which corresponding to a transition in ground-state reversed three-level energy system. For the first time, the spectra of ground-state reversed three-level system transitions were calculated by solving the density matrix equations, and the spectrum characteristics of 918μm line were studied. Experimentally, the CH3OH FIR laser line of 918μm wavelength was obtained by pumping with a TEA-CO2 laser. The experimental results were in good agreement with the theoretical calculations. [ABSTRACT FROM AUTHOR]

By solving the density matrix equations of a quantum system, the output power intensity of an optically pumped CH3OH FIR laser (CH3OH-OPFIRL) was calculated by means of iteration method, and the spectral characteristics were got. Base on the calculation, optimization of operating parameters including operating gas pressure, pumped power and output coupling coefficient of the CH3OH cavity laser were systematically studied. Experimental, a series of FIR emissions of the CH3OH cavity laser pumped by TEA-CO2 laser with 9P(16) line were measured. The experimental results were in good agreement with theoretical calculations. [ABSTRACT FROM AUTHOR]