5 results on '"Carlo Maria Dellino"'
Search Results
2. Multiparametric Mapping via Cardiovascular Magnetic Resonance in the Risk Stratification of Ventricular Arrhythmias and Sudden Cardiac Death
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Maria Lo Monaco, Kamil Stankowski, Stefano Figliozzi, Flavia Nicoli, Vincenzo Scialò, Alessandro Gad, Costanza Lisi, Federico Marchini, Carlo Maria Dellino, Rocco Mollace, Federica Catapano, Giulio Giuseppe Stefanini, Lorenzo Monti, Gianluigi Condorelli, Erika Bertella, and Marco Francone more...
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ventricular arrhythmias ,sudden cardiac death ,cardiovascular magnetic resonance ,mapping ,Medicine (General) ,R5-920 - Abstract
Risk stratification for malignant ventricular arrhythmias and sudden cardiac death is a daunting task for physicians in daily practice. Multiparametric mapping sequences obtained via cardiovascular magnetic resonance imaging can improve the risk stratification for malignant ventricular arrhythmias by unveiling the presence of pathophysiological pro-arrhythmogenic processes. However, their employment in clinical practice is still restricted. The present review explores the current evidence supporting the association between mapping abnormalities and the risk of ventricular arrhythmias in several cardiovascular diseases. The key message is that further clinical studies are needed to test the additional value of mapping techniques beyond conventional cardiovascular magnetic resonance imaging for selecting patients eligible for an implantable cardioverter defibrillator. more...
- Published
- 2024
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- View/download PDF
Catalog
3. New Non-Invasive Imaging Technologies in Cardiac Transplant Follow-Up: Acquired Evidence and Future Options
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Valeria Pergola, Giulia Mattesi, Elena Cozza, Nicola Pradegan, Chiara Tessari, Carlo Maria Dellino, Maria Teresa Savo, Filippo Amato, Annagrazia Cecere, Martina Perazzolo Marra, Francesco Tona, Andrea Igoren Guaricci, Giorgio De Conti, Gino Gerosa, Sabino Iliceto, and Raffaella Motta more...
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heart transplantation ,cardiac allograft vasculopathy ,atrial function ,strain echocardiography ,stress echocardiography ,coronary computed tomography angiography ,Medicine (General) ,R5-920 - Abstract
Heart transplantation (HT) is the established treatment for end-stage heart failure, significantly enhancing patients’ survival and quality of life. To ensure optimal outcomes, the routine monitoring of HT recipients is paramount. While existing guidelines offer guidance on a blend of invasive and non-invasive imaging techniques, certain aspects such as the timing of echocardiographic assessments and the role of echocardiography or cardiac magnetic resonance (CMR) as alternatives to serial endomyocardial biopsies (EMBs) for rejection monitoring are not specifically outlined in the guidelines. Furthermore, invasive coronary angiography (ICA) is still recommended as the gold-standard procedure, usually performed one year after surgery and every two years thereafter. This review focuses on recent advancements in non-invasive and contrast-saving imaging techniques that have been investigated for HT patients. The aim of the manuscript is to identify imaging modalities that may potentially replace or reduce the need for invasive procedures such as ICA and EMB, considering their respective advantages and disadvantages. We emphasize the transformative potential of non-invasive techniques in elevating patient care. Advanced echocardiography techniques, including strain imaging and tissue Doppler imaging, offer enhanced insights into cardiac function, while CMR, through its multi-parametric mapping techniques, such as T1 and T2 mapping, allows for the non-invasive assessment of inflammation and tissue characterization. Cardiac computed tomography (CCT), particularly with its ability to evaluate coronary artery disease and assess graft vasculopathy, emerges as an integral tool in the follow-up of HT patients. Recent studies have highlighted the potential of nuclear myocardial perfusion imaging, including myocardial blood flow quantification, as a non-invasive method for diagnosing and prognosticating CAV. These advanced imaging approaches hold promise in mitigating the need for invasive procedures like ICA and EMB when evaluating the benefits and limitations of each modality. more...
- Published
- 2023
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4. Single coronary artery originating from right sinus. Role of MDCT and a review of literature
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Valeria Pergola, Giulio Cabrelle, Giulio Barbiero, Carlo Maria Dellino, Elena Reffo, Giovanni Di Salvo, and Raffaella Motta
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ECG-gated multidetector computed tomography (MDCT) ,coronary artery anomaly ,single coronary artery ,coronary stenosis ,coronary artery bypass graft ,Medicine - Abstract
SCA from the right sinus is the rarest coronary anomaly. We describe 2 cases: 1 with SCA type-1RI; 2 with SCA type-2RII-A. Appropriate and successful treatment (CABG in case-1; PTCA in case-2) was chosen relying on accurate morphological description provided by MDCT, in order to recognize all the possible mechanisms of myocardial ischemia. more...
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- 2021
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5. Added Value of CCTA-Derived Features to Predict MACEs in Stable Patients Undergoing Coronary Computed Tomography
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Valeria Pergola, Giulio Cabrelle, Giulia Mattesi, Simone Cattarin, Antonio Furlan, Carlo Maria Dellino, Saverio Continisio, Carolina Montonati, Adelaide Giorgino, Chiara Giraudo, Loira Leoni, Riccardo Bariani, Giulio Barbiero, Barbara Bauce, Donato Mele, Martina Perazzolo Marra, Giorgio De Conti, Sabino Iliceto, and Raffaella Motta more...
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coronary computed tomography angiography ,pericoronary fat attenuation index ,low attenuation plaque ,major adverse cardiac events ,plaque analysis ,Medicine (General) ,R5-920 - Abstract
Clinical evidence has emphasized the importance of coronary plaques’ characteristics, rather than lumen stenosis, for the outcome of cardiovascular events. Coronary computed tomographic angiography (CCTA) has a well-established role as a non-invasive tool for assessing plaques. The aim of this study was to compare clinical characteristics and CCTA-derived information of stable patients with non-severe plaques in predicting major adverse cardiac events (MACEs) during follow-up. We retrospectively selected 371 patients (64% male) who underwent CCTA in our center from March 2016 to January 2021 with Coronary Artery Disease—Reporting and Data System (CAD-RADS) 0 to 3. Of those, 198 patients (53% male) had CAD-RADS 0 to 1. Among them, 183 (49%) had normal pericoronary fat attenuation index (pFAI), while 15 (60% male) had pFAI ≥ 70.1 Hounsfield unit (HU). The remaining 173 patients (76% male) had CAD-RADS 2 to 3 and were divided into patients with at least one low attenuation plaque (LAP) and patients without LAPs (n-LAP). Compared to n-LAP, patients with LAPs had higher pFAI (p = 0.005) and had more plaques than patients with n-LAP. Presence of LAPs was significantly higher in elderly (p < 0.001), males (p < 0.001) and patients with traditional risk factors (hypertension p = 0.0001, hyperlipemia p = 0.0003, smoking p = 0.0003, diabetes p = p = 0.0007). Among patients with CAD-RADS 0 to 1, the ones with pFAI ≥ 70.1 HU were more often hyperlipidemic (p = 0.05) and smokers (p = 0.007). Follow-up (25,4 months, range: 17.6–39.2 months) demonstrated that LAP and pFAI ≥ 70.1 significantly and independently (p = 0.04) predisposed to outcomes (overall mortality and interventional procedures). There is an added value of CCTA-derived features in stratifying cardiovascular risk in low- to intermediate-risk patients with non-severe, non-calcified coronary plaques. This is of utmost clinical relevance as it is possible to identify a subset of patients with increased risk who need strengthening in therapeutic management and closer follow-up even in the absence of severe CAD. Further studies are needed to evaluate the effect of medical treatments on pericoronary inflammation and plaque composition. more...
- Published
- 2022
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