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B3LYP/6-31+G(d) and MP2/6-31+G(d) computations are performed on a series of ethynyl- and diethynyl-expanded tetrahedranes, prismanes, cubanes and adamantanes. The poly-ynes express a broad range of absorption energies, indicating that these molecules are potential targets in expressly designed optical applications.

Nuclephilic substitution at selenium is examined using the B3LYP and MP2 methods. Seven different representative substitution reactions involving different nucleophiles and different substrates are examined.

Radiometals play an important role in diagnostic and therapeutic radiopharmaceuticals. This field of radiochemistry is multidisciplinary, involving radiometal production, separation of the radiometal from its target, chelate design for complexing the radiometal in a biologically stable environment, specific targeting of the radiometal to its in vivo site, and nuclear imaging and/or radiotherapy applications of the resultant radiopharmaceutical. The critical importance of inorganic chemistry in the design and application of radiometal-containing imaging and therapy agents is described from a historical perspective to future directions.