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Non-small cell lung cancer (NSCLC) is a leading cause of morbidity and mortality. Carboplatin and cisplatin based regimens are used in the treatment of NSCLC. The aim of the study was to find out whether there is a difference in white matter (WM) changes between two platinum-based chemotherapy agents using diffusion tensor imaging (DTI).

In this research, the Servperf method is used to analyze the quality of health and safety services. The main purpose of this article is to determine the quality level of preventive health and safety services provided in the workplaces within the framework of the perception of the employees who benefit from these services. The questionnaire prepared in accordance with the Servperf method was applied to 412 employees working in various sectors, and the results were classified according to age, gender, education level, sector, and the way of providing (internal & external) services. Descriptive statistics were used in the evaluation of results. The total perceived Servperf score of the health and safety services was 2.84, medium level. As the age and education level of the employees increases, the satisfaction level and Servperf scores of the service quality decrease. The satisfaction score of the construction workers is significantly lower than the other sectors. Satisfaction levels of employees in the workplaces where services are provided internally are higher than those of the workplaces offering external sources. Despite legal regulations related to preventive health and safety services, accidents have not decreased in Turkey. The quality of the service provided by external health and safety units is significantly low. Competition arising from the marketization of occupational health and safety services reduces the quality of the service provided. For these reasons, the number of research aimed at determining the quality of these services should be increased both in Turkey and in the world.

We consider the Gaussian Leonardo numbers and investigate some of their amazing characteristic properties, including their generating function, the associated Binet formula and Cassini identity, and their matrix representation. Then, we define the hybrid Gaussian Leonardo numbers and obtain some of their particular properties. Furthermore, we define nn Hessenberg matrices whose permanents yield the Leonardo and Gaussian Leonardo sequences.

In this study, we introduce a new graph family. Then, we calculate eigenvalues of the adjacency and the Laplacian matrix of this graph family. Moreover, we show that the perfect matching number of this graph family equals to special second order recurrence by hafnian method. For some special kinds of this family, we obtain that the perfect matching number of corresponding graphs equals to some famous number sequences such as Fibonacci, Pell and Jacobsthal numbers. Also, we find energies and obtain upper bounds for Laplacian energies of these graphs.

Focal segmental glomerulosclerosis (FSGS) and other glomerulonephritis due to the use of 5-aminosalicylic acid derivatives have been reported in the literature. A 38-year-old male who had been using mesalazine for four years because of ulcerative colitis applied to doctor due to swelling in the lower extremities. The patient was diagnosed with nephrotic syndrome (NS). Renal biopsy was performed, and FSGS was diagnosed. Antiproteinuric treatments were initiated with steroid therapy. The patient has been followed with the normal renal function of the after treatment. 5-aminosalicylic acid derivatives affect renal functions at different levels and caused in NS.

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Visceral artery aneurysms can be life-threatening conditions with a high incidence of rupture. The endovascular technique with coil embolization is successful procedure for aneurysm treatment. Herein, we presented a case with a new and inexpensive treatment of splenic artery aneurysm by a coronary bare metal stent.

The aim of this study was to determine the relationship between the presence of carotid artery calcification (CAC) and pulp stone (PS). A total of 60 chronic hemodialysis (HD) patients (30 CAC positive, 30 CAC negative) participated in this study. The mean age of patients was 54.7 ± 16.4 years, and 32 (53%) of them were male. CAC was defined as the presence of heterogeneous nodular opacities in the soft tissue in C3–C4 intervertebral area. Panoramic radiographs of the patients were evaluated for CAC and PS by two oral and maxillofacial radiologists. PS was evaluated in all healthy, decayed, and restored teeth except the third molar teeth, in the coronal, sagittal, and axial planes. The Statistical Package for the Social Sciences (version 20.0; SPSS, Inc., an IBM Company, Chicago, IL, USA) was used. A probability P

Thiocolchicoside (TCC) is a widely used centrally acting muscle relaxant. Epileptic seizures from the use of TCC are rarely reported. A 67-year-old male patient with endstage renal disease that was caused by hypertension was on maintenance hemodialysis (HD) for 22 months. He had taken TCC 8 mg capsules twice daily for four days due to painful myofascial spasm in neck and face muscles. At the end of the HD session, he had generalized tonic–clonic seizures. Epileptic seizures were brought under control with sodium valproate, and no recurrence of epileptic seizures was observed.

Bu çalışmada; çoğunluğunu Avrupa ülkelerinin oluşturduğu Paris Liman Devleti Kontrolü Memorandumu (Paris MoU) kapsamında, deniz ve çevre emniyetine ilişkin Türk bayraklı gemilere uygulanan Liman Devleti Denetimlerinin (PSC) sonucu ile denetlenen gemilerin yaşı, tipi, denetim mevsimi, türü ve yeri ile tespit edilen eksiklik sayısı arasındaki ilişkilerin incelenmesi amaçlanmıştır. 2011-2016 yılları arasında Paris MoU’da denetlenen Türk bayraklı gemilere ilişkin verilerin frekans dağılımları verilmiş, söz konusu parametrik olmayan değişkenler arasında istatistiksel olarak belirli bir ilişki olup olmadığı sonucuna varmak için Ki-Kare Testi (χ2) yapılmıştır. Araştırmanın bulguları; 2011-2016 yılları arasındaki dönemde Paris MoU genelinde uygulanan tüm denetimlerde tutulma oranı %3’ler mertebesinde seyrederken, Türk bayraklı gemilerde ise ortalamanın %4,7 olduğu görülmüştür. Türk bayraklı gemilere yönelik denetim ve tutulmalarda en fazla 13 yaş ve üzeri gemilerin öne çıktığı, 5 ve daha fazla sayıda eksiklik tespit edilen PSC denetimlerinin %91,7’sinin tutulma ile sonuçlandığı, gemi yaşı ile denetim sonucu; eksilik sayısı ile denetim sonucu arasında istatistiksel olarak anlamlı ilişki olduğu sonucuna varılmıştır.

Theory of social representations says the group affects its member and at the same time the member affects its group. As people interact with each other, they reconstruct the world socially. This mutual interaction leads to a new type of knowledge. This knowledge is called everyday knowledge. Biological sex does not inform us about issues like gender roles, inequality between genders, women in the workplace whereas gender does; because gender is reconstructed. Language has a role in keeping, transferring and even reconstructing the daily knowledge. At this point, initial and basic aim of this study is to investigate social representations of psychology of gender and women in Turkish Novels from early period of Turkey and 2010’s. Second aim is to compare the social representations between the novels of female and male authors within the same period. The last aim is to see the possible changes in social representations by time according to the female authors and male authors. Male gender roles and objectification of men’s body increase; sexism and violence do not change; marginalization of women decreases but the myth of “men as hero” starts to exist by time. On the other hand, female and male authors generally do not differ from each other at the same time period. This study differs from psychological novel analysis and also novel analysis in Turkish Literature since the study is based on Theory of Social Representations and conducted through Thematic Unit Analysis.

The Pell numbers, named after the English diplomat and mathematician John Pell, are studied by many authors. At this work, by inspiring the definition harmonic numbers, we define harmonic Pell numbers. Moreover, we construct one type of symmetric matrix family whose elements are harmonic Pell numbers and its Hadamard exponential matrix. We investigate some linear algebraic properties and obtain inequalities by using matrix norms. Furthermore, some summation identities for harmonic Pell numbers are obtained. Finally, we give a MATLAB-R2016a code which writes the matrix with harmonic Pell entries and calculates some norms and bounds for the Hadamard exponential matrix.

Background: Hemophagocytic lymphohistiocytosis (HLH) is a life threatening hyper inflammatory disease. Micro RNAs (miRNA) are about 22 nucleotide-long, small RNAs encoded with genes, and they have regulatory functions in immune response. Objective: To determine the miRNA expression levels of 11 secondary HLH patients, we evaluated the associations of miRNA levels with pathogenesis, clinical presentation, and prognosis of the disease. Patients and Methods: Patients who were diagnosed with secondary HLH from January 2011 to December 2012 were included in this study. We profiled the expressions of 379 miRNAs in plasma of both HLH patients and healthy controls. Patients were evaluated regarding with age, clinical findings, miRNA expresions, laboratory data, treatment, and prognosis, by using descriptive statistics. Results: A total of 11 secondary HLH patients and 11 healthy children were included in this study. miR-205-5p was expressed in all case and controls and expression level of miR-205-5p was found 6.21 fold higher than control group (p=0.01). We detected the second highest expression percent in miR-194-5p with 81% of cases and controls. Expression level of miR-194-5p was found to have 163 fold higher than controls (p= 0.009). miR-30c-5p showed 77% expression percent in cases and controls together. The expression level of this miRNA was detected 9 fold decreased in HLH patients compared to healthy children (p= 0.031). Conclusion: We showed that miR-205-5p, miR-194-5p and miR-30c-5p could be useful plasma biomarkers for HLH. Further research is needed in larger and homogenous study groups, especially for these miRNAs as biomarkers for HLH.

Purpose: For assessing the severity of tricuspid regurgitation (TR), there is no gold standard. We developed a parameter, the right ventricular systolic force ratio—RIVIERA, using the continious wave Doppler analysis of TR and pulsed‐wave analysis of the right ventricle outflow tract. We hypothesized that the RIVIERA would facilitate the ability to identify severe TR in clinical settings. Materials and Methods: We obtained data from routine transthoracic echocardiograms. All records reporting no or mild TR (n = 732), moderate TR (n = 584), and severe TR (n = 519) TR were reanalyzed to measure vena contracta (VC) width, TR jet area, effective regurgitant orifice (EROA) derived with the proximal isovelocity surface area method, the RIVIERA, and right‐sided chamber volumes. Results: Significant linear trends were demonstrated for right atrial volume index, end‐diastolic volume index, RVOT velocity time integral, TR jet area, TR‐Vmax, TR‐VTI, TR acceleration, VC width, EROA with increasing TR severity. Independent predictors of severe RT included RIVIERA <4.8, VC width ≥0.7 cm, TR jet area > 10 cm2, and EROA ≥0.4 cm2. Conclusion: The RIVIERA is a feasible, effective, and independent predictor of severe TR that enhances established techniques for estimating TR severity. For clinical decision‐making and management, accurate measurement and classification of TR severity are essential. Therefore, it should be thought about include the RIVIERA in the integrative method to assessing TR severity. [ABSTRACT FROM AUTHOR]

Sillyon was within the ancient region of Pamphylia, and today it is located in the Kocagözler locality of the Yanköy neighborhood of Serik district in Antalya province. The city has preserved its feature of being an important cultural heritage area from past to present with its archaeological, cultural assets, historical values and multi-layered texture. Throughout history, at the point of unification-conflict of cultures and civilizations, Sillyon bears the traces of many civilizations on it. In other words, in light of current data, Sillyon is an example of a multi-layered city that hosts the process of uninterrupted historical settlement from the early Iron Age to the Ottoman period. In this article, the Roman Bridge, which is known as Ayvalıkemer among the people and located on the Koducak Stream, about 1.5 km west of Sillyon, is discussed. The bridge, dated to the Roman Imperial Period, has 3 sections and was built entirely of travertine blocks. The building, which was restored in 2016 with the support of the General Directorate of Highways, is among the strongest examples of bridges in the region. In the study, first of all, the orientation of the building and its entire architectural setup were analyzed. Its historical evaluation was made by comparing it with the contemporary bridges built in Anatolia. Restoration interventions were examined and information about the bridge’s condition before and after restoration was presented. The location of the bridge on the road networks of the Pamphylia Region and its importance for the city were investigated and the connection of Sillyon with the ancient road routes in the region was discussed. It is expected that this article will present a new perspective on both Sillyon research and the ancient transportation network studies in the region.

Varroa destructor mite poses a serious problem for the future of bee populations around the world. Today, there are many commercial drugs with the same and different active ingredients on the market to chemically control over of Varroa destructor. More frequent chemical applications for against Varroa destructor increases stress resilience, colony losses, loss of yield and residue problems in bee products. The scope of this project is aimed to determine the appropriate control method of Varroa by investigating the efficiency values of the evaporation and dropping methods of Oxalic acid. Experimental area were chosen three different apiaries. 28 colonies were determined in each apiary and equalization studies (area with brood, number of bees with bees, age of queen bees, honey, pollen, etc.) were carried out in these colonies. The determined colonies were randomly divided into 4 groups as 7 colonies. The first group is the control group, the second group is applying 2 g of oxalic acid by vaporizing, the third group is 4% oxalic acid 5 ml of sugar syrup (1:1) is dropped between the frames, and in the fourth group, the fight against a drug that is determined by the beekeeper in the market without interfering with the beekeeper. In order to evaluate the data, samples were taken for four periods, before and after spraying in spring and autumn. While the varroa measurements in the group of syrup, vapor and spraying were found to be statistically less than the control group, the syrup, vapor and spraying groups were statistically similar in terms of varroa measurements. Oxalic acid syrup application showed higher efficiency in spring and autumn than vapor application. There is no statistically difference between both two-application method reveals that it can be used as an effective and safe alternative to chemical control against varroa.

In this proposed study, hydrogen and power generation by low-temperature geothermal energy supported Kalina cycle is thermodynamically investigated with an energy and exergy efficiencies approaches. This combined plant includes a Kalina cycle and a PEM electrolysis for power and hydrogen generation. The key purpose of this paper is to generate power and hydrogen in an environmentally benign way. Furthermore, environmental impact analysis is discussed to investigate the carbon dioxide emission that will be released if the power and amount of hydrogen obtained are produced with natural gas. As coming to the examination results, the energy and exergy performance of the overall plant 7.94% and 37.64%, respectively. Also, the net power and hydrogen production rates are computed as 100.5 kW and 0.0001191 kgs-1.

During archaeological excavations at Andriace, the harbour of Myra, an honorific inscription was discovered in front of the quay structure just north of the granarium (horrea Hadriani). It was prepared by Arrius Paetus Themistius, the praeses of Lycia province, to honour the Roman emperor Jovian with a statue. The discovery provides new information about Themistius, who was introduced to us only by the sophist Libanius, including his tria nomina and unexplored service period in Lycia. It has also led to reconsidering the tenure of the praesidatus of two uiri clarissimi, Themistius and Sozomenus. In this context, addenda et corrigenda are proposed for another honorific inscription to emperor Julian in Andriace. Finally, the administrative importance of Myra and Andriace in Lycia during the 4th century is presented.

Museum education course has been made available as a course of professional knowledge in faculties of education since 2018 so that prospective teachers can use museums as learning environments and so that they can plan and do learning activities in those places. This paper aims to analyse prospective elementary school teachers’ views on the elective museum education course. The study was designed as a case study- one of the qualitative research designs. The study group was formed in convenience sampling method. 27 prospective elementary school teachers were included in the study. The research data were collected through the participants’ diaries, open-ended survey questions and focal group interviews; and the data were analysed in the descriptive analysis technique. The research results demonstrated that the prospective teachers developed positive perspectives on museums after taking the museum education course. They thought that the course had inculcated in them personal skills and pedagogical skills. Besides, they also stated that they could benefit from museum education activities in creating effective learning environments in the life of teaching.

Objectives Immune system activation plays a role in resistant hypertension (RHTN) pathogenesis. The clinical effect of the prognostic nutritional index (PNI) on patients with RHTN remains unclear. The aim of this study investigated the possible correlation between PNI and RHTN. Methods In this cross-sectional study, we enrolled 180 adult subjects. In patients were classified into three groups according to their office and ambulatory blood pressure measurements (ABPM): RHTN (n = 60), controlled hypertension (CHTN, n = 60), and normotension-control (NT-C, n = 60). RHTN was defined as BP ≥140/90 mm Hg while taking ≥3 antihypertensive medications or BP

INTRODUCTION: Silent ischemic lesions(CIL) frequently occur after carotid artery stenting(CAS) and are associated with poor long-term prognosis. The effect of blood triglyceride (TG) level on CIL after CAS is yet clear. We investigated the effect of serum TG level on post-procedure CIL in patients undergoing CAS. METHODS: 57 patients who underwent CAS were included in the study, and diffusion-weighted magnetic resonance imaging was conducted before and after CAS. The primary endpoint was new CILs after CAS. The effects of pre-procedural TG, total cholesterol, HDL, and LDL levels on the primary endpoint were investigated. RESULTS: Of the patients 46 (80.7%) were male, median age was 69(60-73) years, and 27 (47.3%) were symptomatic. After the procedure, ipsilateral new CILs were detected in 28 (49.1%) patients. NASCET stenosis %, being symptomatic and using aspirin before the procedure were associated with the presence of new ipsilateral CILs. In multivariate logistic regression analysis, pre-procedural TG level was the only independent predictor of ipsilateral new CILs after the procedure. DISCUSSION AND CONCLUSION: Our study reveals that high TG level is an independent risk factor for new CILs after CAS. Since CILs increase the risk for future ischemic events, TG as a simple, inexpensive, effective, and modifiable marker, can provide information for intense medical treatment, early intervention, and the prognosis.

The aim of this article is to provide quantitative information about occupational health and safety professionals' working conditions and professional independence. The data were obtained through questionnaires applied to employees in the field of occupational health and safety. The validity value of the questions in the questionnaires was calculated as 0.901. The obtained data were analyzed with descriptive statistical techniques. According to the results, the wages and job satisfaction level of occupational health and safety professionals are average, but below what it should be. Health and safety professionals are employed above legal limits. Some of them cannot adequately benefit from their rights such as overtime pay, annual leave, rest breaks and severance pay. On the other hand, there is no job security to ensure the professional independence of health and safety professionals.

Adenomatoid tumours are benign neoplasms of mesothelial origin that most often occur in the epididymis in men and the uterus or fallopian tubes in women. When the stromal smooth muscle component is prominent, the term leiomyoadenomatoid tumour is recommended. To date, only 10 cases of epididymal leiomyoadenomatoid tumour have been reported. In some cases, coagulation necrosis associated with worrisome regenerative changes can occur and leads to an increase in diagnostic pitfalls such as malignant neoplastic processes. Pathologists should be aware of this entity to avoid misdiagnosis. Herein, we present the eleventh case of epididymal leiomyoadenomatoid tumour in a 59-year-old man.

Purpose: Vitamin D deficiency is known that associated with hypertension. Microalbuminuria (MAU) is associated with increased cardiovascular morbidity and mortality. This study aimed to evaluate the relationship between 25-hydroxyvitamin D (25(OH)D) and MAU in newly diagnosed essential hypertension (NDEH) patients. Methods: A total of 116 patients with a diagnosis of NDEH were enrolled in the study. The diagnosis of hypertension was based on ABPM. Patients were divided into 2 groups according to 25(OH)D levels: Group 1: (25(OH)D)>20 ng/mL was defined as Vitamin D sufficiently (VDS), while Group 2: (25(OH)D)

This paper investigated the effect of freezing-thawing and wetting-drying cycles on the strength and durability of clay soil stabilized with lime and marble powder. The test samples were prepared by adding 5%, 10%, 15% and 20% of marble powder, without and with 6% lime to the soil which is a high plasticity clay (CH) according to the Unified Soil Classification System. Unconfined compressive strength tests were performed after 7 and 28 days of curing periods. The durability behavior of the samples was examined by applying freezing-thawing and wetting-drying cycles to the prepared samples. The results of this study show that the presence of marble powder in the soil mixture has an important role in the improvement of strength. An increase in the number of wetting-drying cycles does not decrease the volumetric stability of the samples stabilized with marble powder. The use of lime and marble powder together increased the strength values compared to the natural soil and the use of lime only. It was concluded that the co-use of lime and marble powder had a positive effect on the strength and durability behavior of high plasticity clayey soil.

Objectives: This study aims to compare the outcomes of self-expanding stents (SESs), bare balloon expandable stents (BESs), and covered stents (CSs) in the kissing stent (KS) treatment of aortoiliac bifurcation (AIB) lesions and to identify the predictors of in-stent restenosis (ISR) development. Patients and methods: Between January 2012 and December 2018, a total of 123 patients (108 males, 15 females; mean age: 62.4±9.1 years; range, 37 to 85 years) who had primary KS reconstruction of AIB for symptomatic aortoiliac occlusive disease (AIOD) were retrospectively analyzed. There were 31 patients in the SES group, 56 patients in the BES group, and 36 patients in the CS group. Technical and clinical success, intra- and perioperative complications, determinants of ISR and patency rates were documented. Results: Technical success was achieved in 99.2% of the patients. Clinical symptom improvement was achieved in all three groups (ABI, p=0.45; Rutherford, p=0.35). Median follow-up was 35 (range, 22.5 to 50) months. Primary patency at one and five years were 100% and 82%, respectively for SES, 98% and 88%, for BES, and 92% and 85% for CS (p=0.53). Regression analysis revealed a longer aortic stent length (hazard ratio [HR]: 5.94, 95% confidence interval [CI]: 1.34-26.25, p=0.035) to be significant determinants of ISR. The receiver operating characteristic curve identified 15-mm as the cut-off value with an area under the curve of 0.644. Primary patency rates for [Turk J Vasc Surg 2021; 30(3.000): 190-8]

In this study, Desertifilum tharense cyanobacteria, which has energy generation potential, was firstly isolated from the water sources from Denizli/Turkey, the culture-specific parameters were identified, characterization analyses were performed, and the production in photoreactors under laboratory conditions was performed. D. tharense cyanobacterium was subjected to a high temperature–pressure pretreatment process (HTPP) to increase methane production efficiency, and the pretreatment process was optimized for methane production. D. tharense had a total carbon (C) content of 50.2% and total organic carbon content (TOC) of 48.9%. The biochemical methane potential (BMP) of the raw D. tharense sample was measured as 261.8 mL methane (CH4) per gram of volatile solids (VS). In order to investigate the effects of HTPP and to determine the optimum process conditions, Central Composite Design (CCD) approach-based Response Surface Methodology (RSM) was used. BMP values of the samples treated with HTTP were measured in the range of 201.5–235 mLCH4 gVS−1 and lower than the raw sample. These results revealed that the HTPP is not suitable for the production of biofuel methane from D. tharense. The optimization of the HTPP was carried out by Design Expert software. For maximum BMP production, the software proposed a reaction temperature of 200 °C and a reaction time of 20 min as optimum conditions. With the proposed model, it was estimated that 227.1 mLCH4 g VS−1 methane could be produced under these conditions, and 211.4 mLCH4 g VS−1 methane was produced in the validation experiment. It was determined that D. tharense cyanobacterium could be used as a suitable biomass source for methane production. However, it was not necessary to use the HTTP as a pretreatment process prior to the methane production.