1,458 results on '"Goldstein, Daniel"'
Search Results
2. Clonally expanded memory CD8+ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice
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Tyrrell, Daniel J., Wragg, Kathleen M., Chen, Judy, Wang, Hui, Song, Jianrui, Blin, Muriel G., Bolding, Chase, Vardaman, III, Donald, Giles, Kara, Tidwell, Harrison, Ali, Md Akkas, Janappareddi, Abhinav, Wood, Sherri C., and Goldstein, Daniel R.
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- 2023
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3. The 2019 data challenge expo of the American Statistical Association
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Goldstein, Daniel, Gaumer, Elyzabeth, and Martinez, Wendy
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- 2023
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4. Publisher Correction: Clonally expanded memory CD8+ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice
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Tyrrell, Daniel J., Wragg, Kathleen M., Chen, Judy, Wang, Hui, Song, Jianrui, Blin, Muriel G., Bolding, Chase, Vardaman, III, Donald, Giles, Kara, Tidwell, Harrison, Ali, Md Akkas, Janappareddi, Abhinav, Wood, Sherri C., and Goldstein, Daniel R.
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- 2024
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5. The Spirit of an Age: Iowa Public Libraries and Professional Librarians as Solutions to Society's Problems, 1890-1940
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Goldstein, Daniel
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- 2003
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6. Desconfianza and Problems of Representation in Urban Ethnography
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Goldstein, Daniel M.
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- 2002
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7. Extended duration of treatment using reduced-frequency dosing of anti-PD-1 therapy in patients with advanced melanoma and Merkel cell carcinoma
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Tachiki, Lisa May Ling, Hippe, Daniel S., Williams Silva, Karly, Hall, Evan Thomas, McCamy, William, Fritzsche, Dane, Perdue, Andrea, Majovski, Julia, Pulliam, Thomas, Goldstein, Daniel A., Veatch, Joshua, Ho, Joel, Nghiem, Paul T., Thompson, John A., and Bhatia, Shailender
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- 2023
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8. Interventional pharmacoeconomics for immune checkpoint inhibitors through alternative dosing strategies
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Wesevich, Austin, Goldstein, Daniel A., Paydary, Koosha, Peer, Cody J., Figg, William D., and Ratain, Mark J.
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- 2023
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9. The Immunomodulatory Effects of Dexamethasone on Neoadjuvant Chemotherapy for Triple-Negative Breast Cancer
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Johnson, Kai Conrad Cecil, Goldstein, Daniel, Tharakan, Jasmin, Quiroga, Dionisia, Kassem, Mahmoud, Grimm, Michael, Miah, Abdul, Vargo, Craig, Berger, Michael, Sudheendra, Preeti, Pariser, Ashley, Gatti-Mays, Margaret E., Williams, Nicole, Stover, Daniel, Sardesai, Sagar, Wesolowski, Robert, Ramaswamy, Bhuvaneswari, Tozbikian, Gary, Schnell, Patrick M., and Cherian, Mathew A.
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- 2023
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10. Evo’s Bolivia: Continuity and Change by Linda C. Farthing and Benjamin H. Kohl (review)
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Goldstein, Daniel M.
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- 2015
11. Lactate Dehydrogenase and Hemorrhagic Stroke During Extracorporeal Membrane Oxygenation for COVID-19
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Nunez, Jose I., Uehara, Mayuko, Mohamed, Amira, Mellas, Nicholas, Ashley, Justin E., Rahmanian, Marjan, Carlese, Anthony, Forest, Stephen J., Goldstein, Daniel, Jorde, Ulrich, and Saeed, Omar
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- 2023
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12. Efficient ancestry and mutation simulation with msprime 1.0
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Baumdicker, Franz, Bisschop, Gertjan, Goldstein, Daniel, Gower, Graham, Ragsdale, Aaron P, Tsambos, Georgia, Zhu, Sha, Eldon, Bjarki, Ellerman, E Castedo, Galloway, Jared G, Gladstein, Ariella L, Gorjanc, Gregor, Guo, Bing, Jeffery, Ben, Kretzschumar, Warren W, Lohse, Konrad, Matschiner, Michael, Nelson, Dominic, Pope, Nathaniel S, Quinto-Cortés, Consuelo D, Rodrigues, Murillo F, Saunack, Kumar, Sellinger, Thibaut, Thornton, Kevin, van Kemenade, Hugo, Wohns, Anthony W, Wong, Yan, Gravel, Simon, Kern, Andrew D, Koskela, Jere, Ralph, Peter L, and Kelleher, Jerome
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Algorithms ,Computer Simulation ,Genetics ,Population ,Models ,Genetic ,Mutation ,Software ,simulation ,coalescent ,mutations ,Ancestral Recombination Graphs ,Genetics ,Developmental Biology - Abstract
Stochastic simulation is a key tool in population genetics, since the models involved are often analytically intractable and simulation is usually the only way of obtaining ground-truth data to evaluate inferences. Because of this, a large number of specialized simulation programs have been developed, each filling a particular niche, but with largely overlapping functionality and a substantial duplication of effort. Here, we introduce msprime version 1.0, which efficiently implements ancestry and mutation simulations based on the succinct tree sequence data structure and the tskit library. We summarize msprime's many features, and show that its performance is excellent, often many times faster and more memory efficient than specialized alternatives. These high-performance features have been thoroughly tested and validated, and built using a collaborative, open source development model, which reduces duplication of effort and promotes software quality via community engagement.
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- 2022
13. Association of tricuspid regurgitation with clinical events and quality of life after surgery for severe ischemic mitral regurgitation
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Strobel, Raymond J., Kramer, Benjamin P., Overbey, Jessica R., Mehaffey, J. Hunter, Hawkins, Robert B., II, Gammie, James S., Gillinov, Marc, Acker, Michael A., Kramer, Robert S., Smith, Peter K., Kron, Irving L., Voisine, Pierre, Taddei-Peters, Wendy C., Geller, Nancy L., Dagenais, François, Mack, Michael J., Moquete, Ellen G., Marks, Mary E., Iribarne, Alexander, Goldstein, Daniel J., Ailawadi, Gorav, O'Gara, Patrick T., Moskowitz, Alan J., Gelijns, Annetine C., and Bagiella, Emilia
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- 2024
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14. Deactivation of LVAD support for myocardial recovery—surgical perspectives
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Nickel, Ian, Potapov, Evgenij, Sun, Benjamin, Zimpfer, Daniel, Koliopoulou, Antigone, Adachi, Iki, Anyanwu, Anelechi, Falk, Volkmar, Atluri, Pavan, Faerber, Gloria, Goldstein, Daniel, Yarboro, Leora, Slaughter, Mark S., Milano, Carmelo, Tsukashita, Masaki, D’Alessandro, David, Silvestry, Scott, Kirov, Hristo, Bommareddi, Swaroop, Lanmüller, Pia, Doenst, Torsten, and Selzman, Craig H.
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- 2024
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15. Intimal hyperplasia, saphenous vein graft disease, and clinical outcomes: Insights from the CTSN VEST randomized trial
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Goldstein, Daniel J., Chang, Helena L., Mack, Michael J., Voisine, Pierre, Gammie, James S., Marks, Mary E., Iribarne, Alexander, Vengrenyuk, Yuliya, Raymond, Samantha, Taylor, Bradley S., Dagenais, François, Ailawadi, Gorav, Chu, Michael W.A., DiMaio, J. Michael, Narula, Jagat, Moquete, Ellen G., O'Sullivan, Karen, Williams, Judson B., Jr., Crestanello, Juan A., Scavo, Vincent, Puskas, John D., Acker, Michael A., Gillinov, Marc, Gelijns, Annetine C., O'Gara, Patrick T., Moskowitz, Alan J., Alexander, John H., and Bagiella, Emilia
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- 2024
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16. A multicenter evaluation of external outflow graft obstruction with a fully magnetically levitated left ventricular assist device
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Wert, Leonhard, Stewart, Garrick C., Mehra, Mandeep R., Milwidsky, Assi, Jorde, Ulrich P., Goldstein, Daniel J., Selzman, Craig H., Stehlik, Josef, Alshamdin, Faisal D., Khaliel, Feras H., Gustafsson, Finn, Boschi, Silvia, Loforte, Antonio, Ajello, Silvia, Scandroglio, Anna M., Tučanová, Zuzana, Netuka, Ivan, Schlöglhofer, Thomas, Zimpfer, Daniel, Zijderhand, Casper F., Caliskan, Kadir, Dogan, Günes, Schmitto, Jan D., Maier, Sven, Schibilsky, David, Jawad, Khalil, Saeed, Diyar, Faerber, Gloria, Morshuis, Michiel, Hanuna, Maja, Müller, Christoph S., Mulzer, Johanna, Kempfert, Jörg, Falk, Volkmar, and Potapov, Evgenij V.
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- 2024
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17. Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice
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Song, Jianrui, Zhang, Yanling, Frieler, Ryan A., Andren, Anthony, Wood, Sherri, Tyrrell, Daniel J., Sajjakulnukit, Peter, Deng, Jane C., Lyssiotis, Costas A., Mortensen, Richard M., Salmon, Morgan, and Goldstein, Daniel R.
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Inflammation -- Health aspects ,Genes -- Health aspects ,Metabolites -- Health aspects ,B cells -- Health aspects ,Macrophages -- Health aspects ,Enzymes -- Health aspects ,Anti-inflammatory drugs -- Health aspects ,Atherosclerosis -- Health aspects ,Health care industry - Abstract
Itaconate has emerged as a critical immunoregulatory metabolite. Here, we examined the therapeutic potential of itaconate in atherosclerosis. We found that both itaconate and the enzyme that synthesizes it, aconitate decarboxylase 1 (Acod1, also known as immune-responsive gene 1 [IRG1]), are upregulated during atherogenesis in mice. Deletion of Acodl in myeloid cells exacerbated inflammation and atherosclerosis in vivo and resulted in an elevated frequency of a specific subset of M1-polarized proinflammatory macrophages in the atherosclerotic aorta. Importantly, Acod1 levels were inversely correlated with clinical occlusion in atherosclerotic human aorta specimens. Treating mice with the itaconate derivative 4- octyl itaconate attenuated inflammation and atherosclerosis induced by high cholesterol. Mechanistically, we found that the antioxidant transcription factor, nuclear factor erythroid 2-related factor 2 (Nrf2), was required for itaconate to suppress macrophage activation induced by oxidized lipids in vitro and to decrease atherosclerotic lesion areas in vivo. Overall, our work shows that itaconate suppresses atherogenesis by inducing Nrf2-dependent inhibition of proinflammatory responses in macrophages. Activation of the itaconate pathway may represent an important approach to treat atherosclerosis., Introduction Itaconate has emerged as a compelling immunomodulatory metabolite produced in the tricarboxylic acid (TCA) cycle (1, 2). The enzyme cis-aconitate decarboxylase 1 (Acod1, also named Irg1) is responsible for [...]
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- 2024
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18. The impact of perioperative stroke and delirium on outcomes after surgical aortic valve replacement
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Miller, Marissa A., Taddei-Peters, Wendy C., Jeffries, Neal O., Buxton, Dennis, Geller, Nancy L., Gordon, David, Burke, Catherine, Lee, Albert, Smith, Tyrone, Moy, Claudia S., Gombos, Ilana Kogan, Weisel, Richard, Gardner, Timothy J., O'Gara, Patrick T., Rose, Eric A., Gelijns, Annetine C., Parides, Michael K., Ascheim, Deborah D., Moskowitz, Alan J., Bagiella, Emilia, Moquete, Ellen, Shah, Kinjal, Overbey, Jessica R., Pan, Stephanie, Chang, Helena, Chase, Melissa, Goldfarb, Seth, Gupta, Lopa, Kirkwood, Katherine, Dobrev, Edlira, Levitan, Ron, O'Sullivan, Karen, Santos, Milerva, Ye, Xia, Mack, Michael, Winkle, Rachelle, Boswell, Haley, Fenlon, Amanda, Johnson, Melissa, Jones, Jessica, Kolb, Megan, Lam, Sarah, Miranda, Lucy, Ward, Jackie, Whitman, Renessa, Zingler, Brittany, Ryan, William, Smith, Robert L., Grayburn, Paul, Nosnik, Pedro, Gillinov, A. Marc, Blackstone, Eugene H., Moazami, Nader, Starling, Randall C., Barzilai, Benico, Grimm, Richard A., Soltesz, Edward G., Katzan, Irene, Strippy, Brian, Smith, Shoi, Garcia, Michelle, Alice bowman, Mary, Geither, Carrie, Wang, Robert, Argenziano, Michael, Borger, Michael, Takayama, Hiroo, Leon, Martin B., Goldsmith, Lyn, Schwartz, Allan, Sookraj, Nadia, McCright-Gill, Talaya, Sreekanth, Sowmya, McCullough, Jock N., Iribarne, Alexander, DeSimone, Joseph P., DiScipio, Anthony W., Stokes, Henry, Ivany, Amanda St., Petty, Gaylin, Smith, Peter K., Alexander, John H., Milano, Carmelo A., Glower, Donald D., Huber, Joel, Morganlander, Joel, Mathew, Joseph P., Welsh, Stacey, Casalinova, Sarah, Johnson, Victoria, Lane, Kathleen, Smith, Derek, Tipton, Greg, Berry, Mark F., Williams, Judson B., Englum, Brian, Hartwig, Matthew, Thourani, Vinod H., Guyton, Robert, Lattouf, Omar, Chen, Edward, Vega, J. David, Baer, Jefferson, Nguyen, Duc, Halkos, Michael, Baio, Kim, Prince, Tamara, Cook, Natascha, Neill, Alexis A., Voisine, Pierre, Senechal, Mario, Dagenais, François, Laforce, Robert, Jr., O'Connor, Kim, Dussault, Gladys, Caouette, Manon, Tremblay, Hugo, Gagne, Nathalie, Dumont, Julie, Landry, Patricia, Groh, Mark A., Trichon, Benjamin H., Binns, Oliver A., Ely, Stephen W., Johnson, Alan M., Hansen, Todd H., Short, John G., Taylor, Reid D., Mangusan, Ralph, Nanney, Tracy, Aubart, Holly, Cross, Kristin, McPeters, Leslie, Riggsbee, Christina, Rixey, Lucy, Michler, Robert E., DeRose, Joseph J., Jr., Goldstein, Daniel J., Bello, Ricardo A., Taub, Cynthia, Spevack, Daniel, Kirchoff, Kathryn, Meli, Rebecca, Garcia, Juan, Goldenberg, Jon, Kealy, Lauren, Perrault, Louis P., Bouchard, Denis, Tanguay, Jean François, O'Meara, Eileen, Lacharité, Jonathan, Robichaud, Sophie, Horvath, Keith A., Corcoran, Philip C., Siegenthaler, Michael P., Murphy, Mandy, Iraola, Margaret, Greenberg, Ann, Kumkumian, Greg, Milner, Mark, Nadareishvili, Zurab, Whitson, Bryan A., Hasan, Ayesha, McDavid, Asia, Fadorsen, Denise, Ouzounian, Maral, Yau, Terry, Farkouh, Michael, Woo, Anna, Cusimano, Robert James, David, Tirone, Feindel, Christopher, Fumakia, Nishit, Christie, Shakira, Mullen, John C., Bissonauth, Asvina, Hripko, Alexandra, Gammie, James S., Noor, Zahid, Mackowick, Kristen, Deasey, Stephanie, Al-Suqi, Manal, Collins, Julia, Acker, Michael A., Messé, Steven, Kirkpatrick, James, Mayer, Mary Lou, McDonald, Caitlin, Fok, Holley, Maffei, Breanna, Cresse, Stephen, Gepty, Christine, Bowdish, Michael, Starnes, Vaughn A., Shavalle, David, Heck, Christi, Hackmann, Amy, Baker, Craig, Fleischman, Fernando, Cunningham, Mark, Lozano, Edward, Hernandez, Michelle, Ailawadi, Gorav, Kron, Irving L., Johnston, Karen, Ghanta, Ravi K., Dent, John M., Kern, John, Yarboro, Leora, Ragosta, Michael, Annex, Brian, Bergin, Jim, Burks, Sandra, Cosner, Mike, Green, China, Loya, Samantha, Kim, Hye Ryun, Bull, David A., Desvigne-Nickens, Patrice, Dixon, Dennis O., Gottesman, Rebecca, Haigney, Mark, Holubkov, Richard, Iadecola, Constantino, Jacobs, Alice, Meslin, Eric M., Murkin, John M., Spertus, John A., Sellke, Frank, McDonald, Cheryl L., Canty, John, Dickert, Neal, Ikonomidis, John S., Kim, KyungMann, Williams, David O., Yancy, Clyde W., Chaturvedi, Seemant, Chimowitz, Marc, Fang, James C., Richenbacher, Wayne, Rao, Vivek, Furie, Karen L., Miller, Rachel, Cook, Jennifer, D'Alessandro, David, Han, Frederick, Pinney, Sean, Walsh, Mary N., Greer, David, Ishida, Koto, Stapf, Christian, Hung, Judy, Zeng, Xin, Hung, David, Satitthummanid, Sudarat, Billelo, Michel, Davatzikos, Christos, Erus, Guray, Karpf, Lauren, Desiderio, Lisa, Browndyke, Jeffrey N., James, Michael L., Toulgoat-Dubois, Yanne, Brassard, Rachele, Virmanu, Renu, Romero, Maria E., Braumann, Ryan, Messé, Steven R., Mack, Michael J., Southerland, Andrew M., Moy, Claudia Scala, and Bowdish, Michael E.
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- 2024
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19. Extrinsic outflow graft obstruction of the HeartMate 3 LVAD: A state-of-the-art review
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Goldstein, Daniel J., Kanwar, Manreet, Cowger, Jennifer, Patel, Snehal, Meyer, Dan M., Molina, Ezequiel, Salerno, Christopher, Elmer, Ashley, Schettle, Sarah, Teuteberg, Jeffrey, Pagani, Francis, and Stehlik, Josef
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- 2024
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20. Correction to: Extended duration of treatment using reduced‑frequency dosing of anti‑PD‑1 therapy in patients with advanced melanoma and Merkel cell carcinoma
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Tachiki, Lisa May Ling, Hippe, Daniel S., Silva, Karly Williams, Hall, Evan Thomas, McCamy, William, Fritzsche, Dane, Perdue, Andrea, Majovski, Julia, Pulliam, Thomas, Goldstein, Daniel A., Veatch, Joshua, Ho, Joel, Nghiem, Paul T., Thompson, John A., and Bhatia, Shailender
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- 2023
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21. Clinical Outcomes With a Fully Magnetically Levitated Left Ventricular Assist Device Among Women and Men
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Ramu, Bhavadharini, Cogswell, Rebecca, Ravichandran, Ashwin K., Cleveland, Joseph, Jr., Mehra, Mandeep R., Goldstein, Daniel, Uriel, Nir, Dirckx, Nicholas, Ahmed, Sara, and Yuzefpolskaya, Melana
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- 2023
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22. Bright, Months-long Stellar Outbursts Announce the Explosion of Interaction-powered Supernovae
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Strotjohann, Nora L, Ofek, Eran O, Gal-Yam, Avishay, Bruch, Rachel, Schulze, Steve, Shaviv, Nir, Sollerman, Jesper, Filippenko, Alexei V, Yaron, Ofer, Fremling, Christoffer, Nordin, Jakob, Kool, Erik C, Perley, Dan A, Ho, Anna YQ, Yang, Yi, Yao, Yuhan, Soumagnac, Maayane T, Graham, Melissa L, Barbarino, Cristina, Tartaglia, Leonardo, De, Kishalay, Goldstein, Daniel A, Cook, David O, Brink, Thomas G, Taggart, Kirsty, Yan, Lin, Lunnan, Ragnhild, Kasliwal, Mansi, Kulkarni, Shri R, Nugent, Peter E, Masci, Frank J, Rosnet, Philippe, Adams, Scott M, Andreoni, Igor, Bagdasaryan, Ashot, Bellm, Eric C, Burdge, Kevin, Duev, Dmitry A, Dugas, Alison, Frederick, Sara, Goldwasser, Samantha, Hankins, Matthew, Irani, Ido, Karambelkar, Viraj, Kupfer, Thomas, Liang, Jingyi, Neill, James D, Porter, Michael, Riddle, Reed L, Sharma, Yashvi, Short, Phil, Taddia, Francesco, Tzanidakis, Anastasios, van Roestel, Jan, Walters, Richard, and Zhuang, Zhuyun
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Eruptive phenomena ,Stellar mass loss ,Circumstellar matter ,Late stellar evolution ,Stellar flares ,Core-collapse supernovae ,astro-ph.HE ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) ,Astronomy & Astrophysics - Abstract
Interaction-powered supernovae (SNe) explode within an optically thick circumstellar medium (CSM) that could be ejected during eruptive events. To identify and characterize such pre-explosion outbursts, we produce forcedphotometry light curves for 196 interacting SNe, mostly of Type IIn, detected by the Zwicky Transient Facility between early 2018 and 2020 June. Extensive tests demonstrate that we only expect a few false detections among the 70,000 analyzed pre-explosion images after applying quality cuts and bias corrections. We detect precursor eruptions prior to 18 Type IIn SNe and prior to the Type Ibn SN 2019uo. Precursors become brighter and more frequent in the last months before the SN and month-long outbursts brighter than magnitude -13 occur prior to 25% (5-69%, 95% confidence range) of all Type IIn SNe within the final three months before the explosion. With radiative energies of up to 1049erg, precursors could eject ~1M⊙of material. Nevertheless, SNe with detected precursors are not significantly more luminous than other SNe IIn, and the characteristic narrow hydrogen lines in their spectra typically originate from earlier, undetected mass-loss events. The long precursor durations require ongoing energy injection, and they could, for example, be powered by interaction or by a continuum-driven wind. Instabilities during the neon- and oxygen-burning phases are predicted to launch precursors in the final years to months before the explosion; however, the brightest precursor is 100 times more energetic than anticipated.
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- 2021
23. Kilonova Luminosity Function Constraints Based on Zwicky Transient Facility Searches for 13 Neutron Star Merger Triggers during O3
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Kasliwal, Mansi M, Anand, Shreya, Ahumada, Tomás, Stein, Robert, Carracedo, Ana Sagués, Andreoni, Igor, Coughlin, Michael W, Singer, Leo P, Kool, Erik C, De, Kishalay, Kumar, Harsh, AlMualla, Mouza, Yao, Yuhan, Bulla, Mattia, Dobie, Dougal, Reusch, Simeon, Perley, Daniel A, Cenko, S Bradley, Bhalerao, Varun, Kaplan, David L, Sollerman, Jesper, Goobar, Ariel, Copperwheat, Christopher M, Bellm, Eric C, Anupama, GC, Corsi, Alessandra, Nissanke, Samaya, Agudo, Iván, Bagdasaryan, Ashot, Barway, Sudhanshu, Belicki, Justin, Bloom, Joshua S, Bolin, Bryce, Buckley, David AH, Burdge, Kevin B, Burruss, Rick, Caballero-García, Maria D, Cannella, Chris, Castro-Tirado, Alberto J, Cook, David O, Cooke, Jeff, Cunningham, Virginia, Dahiwale, Aishwarya, Deshmukh, Kunal, Dichiara, Simone, Duev, Dmitry A, Dutta, Anirban, Feeney, Michael, Franckowiak, Anna, Frederick, Sara, Fremling, Christoffer, Gal-Yam, Avishay, Gatkine, Pradip, Ghosh, Shaon, Goldstein, Daniel A, Golkhou, V Zach, Graham, Matthew J, Graham, Melissa L, Hankins, Matthew J, Helou, George, Hu, Youdong, Ip, Wing-Huen, Jaodand, Amruta, Karambelkar, Viraj, Kong, Albert KH, Kowalski, Marek, Khandagale, Maitreya, Kulkarni, SR, Kumar, Brajesh, Laher, Russ R, Li, KL, Mahabal, Ashish, Masci, Frank J, Miller, Adam A, Mogotsi, Moses, Mohite, Siddharth, Mooley, Kunal, Mroz, Przemek, Newman, Jeffrey A, Ngeow, Chow-Choong, Oates, Samantha R, Patil, Atharva Sunil, Pandey, Shashi B, Pavana, M, Pian, Elena, Riddle, Reed, Sánchez-Ramírez, Rubén, Sharma, Yashvi, Singh, Avinash, Smith, Roger, Soumagnac, Maayane T, Taggart, Kirsty, Tan, Hanjie, Tzanidakis, Anastasios, Troja, Eleonora, Valeev, Azamat F, Walters, Richard, Waratkar, Gaurav, Webb, Sara, and Yu, Po-Chieh
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Neutron stars ,Black holes ,Gravitational waves ,Nucleosynthesis ,R-process ,Compact objects ,Spectroscopy ,Sky surveys ,Photometry ,astro-ph.HE ,astro-ph.IM ,astro-ph.SR ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) ,Astronomy & Astrophysics - Abstract
We present a systematic search for optical counterparts to 13 gravitational wave (GW) triggers involving at least one neutron star during LIGO/Virgo's third observing run (O3). We searched binary neutron star (BNS) and neutron star black hole (NSBH) merger localizations with the Zwicky Transient Facility (ZTF) and undertook follow-up with the Global Relay of Observatories Watching Transients Happen (GROWTH) collaboration. The GW triggers had a median localization area of 4480 deg2, a median distance of 267 Mpc, and false-alarm rates ranging from 1.5 to 10-25 yr-1. The ZTF coverage in the g and r bands had a median enclosed probability of 39%, median depth of 20.8 mag, and median time lag between merger and the start of observations of 1.5 hr. The O3 follow-up by the GROWTH team comprised 340 UltraViolet/Optical/InfraRed (UVOIR) photometric points, 64 OIR spectra, and three radio images using 17 different telescopes. We find no promising kilonovae (radioactivity-powered counterparts), and we show how to convert the upper limits to constrain the underlying kilonova luminosity function. Initially, we assume that all GW triggers are bona fide astrophysical events regardless of false-alarm rate and that kilonovae accompanying BNS and NSBH mergers are drawn from a common population; later, we relax these assumptions. Assuming that all kilonovae are at least as luminous as the discovery magnitude of GW170817 (-16.1 mag), we calculate that our joint probability of detecting zero kilonovae is only 4.2%. If we assume that all kilonovae are brighter than-16.6 mag (the extrapolated peak magnitude of GW170817) and fade at a rate of 1 mag day-1 (similar to GW170817), the joint probability of zero detections is 7%. If we separate the NSBH and BNS populations based on the online classifications, the joint probability of zero detections, assuming all kilonovae are brighter than-16.6 mag, is 9.7% for NSBH and 7.9% for BNS mergers. Moreover, no more than 10-4, or φ > 30° to be consistent with our limits. We look forward to searches in the fourth GW observing run; even 17 neutron star mergers with only 50% coverage to a depth of-16 mag would constrain the maximum fraction of bright kilonovae to
- Published
- 2020
24. Predictors of 5-Year Mortality in Patients Managed With a Magnetically Levitated Left Ventricular Assist Device
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Nayak, Aditi, Hall, Shelley A., Uriel, Nir, Goldstein, Daniel J., Cleveland, Joseph C., Jr., Cowger, Jennifer A., Salerno, Christopher T., Naka, Yoshifumi, Horstmanshof, Douglas, Crandall, Daniel, Wang, AiJia, and Mehra, Mandeep R.
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- 2023
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25. SN 2020bvc: A Broad-line Type Ic Supernova with a Double-peaked Optical Light Curve and a Luminous X-Ray and Radio Counterpart
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Ho, Anna YQ, Kulkarni, SR, Perley, Daniel A, Cenko, S Bradley, Corsi, Alessandra, Schulze, Steve, Lunnan, Ragnhild, Sollerman, Jesper, Gal-Yam, Avishay, Anand, Shreya, Barbarino, Cristina, Bellm, Eric C, Bruch, Rachel J, Burns, Eric, De, Kishalay, Dekany, Richard, Delacroix, Alexandre, Duev, Dmitry A, Frederiks, Dmitry D, Fremling, Christoffer, Goldstein, Daniel A, Golkhou, V Zach, Graham, Matthew J, Hale, David, Kasliwal, Mansi M, Kupfer, Thomas, Laher, Russ R, Martikainen, Julia, Masci, Frank J, Neill, James D, Ridnaia, Anna, Rusholme, Ben, Savchenko, Volodymyr, Shupe, David L, Soumagnac, Maayane T, Strotjohann, Nora L, Svinkin, Dmitry S, Taggart, Kirsty, Tartaglia, Leonardo, Yan, Lin, and Zolkower, Jeffry
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Astronomical Sciences ,Physical Sciences ,Radio transient sources ,High energy astrophysics ,Transient sources ,Core-collapse supernovae ,Supernovae ,Type Ic supernovae ,X-ray transient sources ,Surveys ,Gamma-ray bursts ,astro-ph.HE ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) ,Astronomy & Astrophysics ,Astronomical sciences ,Particle and high energy physics ,Space sciences - Abstract
We present optical, radio, and X-ray observations of SN 2020bvc (=ASASSN-20bs, ZTF 20aalxlis), a nearby broad-line (BL) Type Ic supernova (SN) and the first double-peaked Ic-BL discovered without a gamma-ray burst (GRB) trigger. Our observations show that SN 2020bvc shares several properties in common with the Ic-BL SN 2006aj, which was associated with the low-luminosity gamma-ray burst (LLGRB) 060218. First, the 10 GHz radio luminosity is brighter than ordinary core-collapse SNe but fainter than LLGRB SNe such as SN 1998bw (associated with LLGRB 980425). We model our VLA observations (spanning 13-43 days) as synchrotron emission from a mildly relativistic (v 0.3c) forward shock. Second, with Swift and Chandra, we detect X-ray emission (L X 1041 erg that is not naturally explained as inverse Compton emission or part of the same synchrotron spectrum as the radio emission. Third, high-cadence (6× night-1) data from the Zwicky Transient Facility (ZTF) show a double-peaked optical light curve, the first peak from shock cooling of extended low-mass material (mass SN 2020bvc is the first double-peaked Ic-BL SN discovered without a GRB trigger, so it is noteworthy that it shows X-ray and radio emission similar to LLGRB SNe. For four of the five other nearby (z ≲ 0.05) Ic-BL SNe with ZTF high-cadence data, we rule out a first peak like that seen in SN 2006aj and SN 2020bvc, i.e., that lasts 1 day and reaches a peak luminosity M -18. Follow-up X-ray and radio observations of Ic-BL SNe with well-sampled early optical light curves will establish whether double-peaked optical light curves are indeed predictive of LLGRB-like X-ray and radio emission.
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- 2020
26. Reducing opinion polarization : Effects of exposure to similar people with differing political views
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Balietti, Stefano, Getoor, Lise, Goldstein, Daniel G., and Watts, Duncan J.
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- 2021
27. GROWTH on S190814bv: Deep Synoptic Limits on the Optical/Near-infrared Counterpart to a Neutron Star–Black Hole Merger
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Andreoni, Igor, Goldstein, Daniel A, Kasliwal, Mansi M, Nugent, Peter E, Zhou, Rongpu, Newman, Jeffrey A, Bulla, Mattia, Foucart, Francois, Hotokezaka, Kenta, Nakar, Ehud, Nissanke, Samaya, Raaijmakers, Geert, Bloom, Joshua S, De, Kishalay, Jencson, Jacob E, Ward, Charlotte, Ahumada, Tomás, Anand, Shreya, Buckley, David AH, Caballero-García, Maria D, Castro-Tirado, Alberto J, Copperwheat, Christopher M, Coughlin, Michael W, Cenko, S Bradley, Gromadzki, Mariusz, Hu, Youdong, Karambelkar, Viraj R, Perley, Daniel A, Sharma, Yashvi, Valeev, Azamat F, Cook, David O, Fremling, U Christoffer, Kumar, Harsh, Taggart, Kirsty, Bagdasaryan, Ashot, Cooke, Jeff, Dahiwale, Aishwarya, Dhawan, Suhail, Dobie, Dougal, Gatkine, Pradip, Golkhou, V Zach, Goobar, Ariel, Chaves, Andreas Guerra, Hankins, Matthew, Kaplan, David L, Kong, Albert KH, Kool, Erik C, Mohite, Siddharth, Sollerman, Jesper, Tzanidakis, Anastasios, Webb, Sara, and Zhang, Keming
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Astronomical Sciences ,Physical Sciences ,Vaccine Related ,astro-ph.HE ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) ,Astronomy & Astrophysics ,Astronomical sciences ,Particle and high energy physics ,Space sciences - Abstract
On 2019 August 14, the Advanced LIGO and Virgo interferometers detected the high-significance gravitational wave (GW) signal S190814bv. The GW data indicated that the event resulted from a neutron star-black hole (NSBH) merger, or potentially a low-mass binary BH merger. Due to the low false-alarm rate and the precise localization (23 deg2 at 90%), S190814bv presented the community with the best opportunity yet to directly observe an optical/near-infrared counterpart to an NSBH merger. To search for potential counterparts, the GROWTH Collaboration performed real-time image subtraction on six nights of public Dark Energy Camera images acquired in the 3 weeks following the merger, covering >98% of the localization probability. Using a worldwide network of follow-up facilities, we systematically undertook spectroscopy and imaging of optical counterpart candidates. Combining these data with a photometric redshift catalog, we ruled out each candidate as the counterpart to S190814bv and placed deep, uniform limits on the optical emission associated with S190814bv. For the nearest consistent GW distance, radiative transfer simulations of NSBH mergers constrain the ejecta mass of S190814bv to be M ej < 0.04 M o˙ at polar viewing angles, or M ej < 0.03 M o˙ if the opacity is κ < 2 cm2g-1. Assuming a tidal deformability for the NS at the high end of the range compatible with GW170817 results, our limits would constrain the BH spin component aligned with the orbital momentum to be χ < 0.7 for mass ratios Q < 6, with weaker constraints for more compact NSs.
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- 2020
28. Evidence for Late-stage Eruptive Mass Loss in the Progenitor to SN2018gep, a Broad-lined Ic Supernova: Pre-explosion Emission and a Rapidly Rising Luminous Transient
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Ho, Anna YQ, Goldstein, Daniel A, Schulze, Steve, Khatami, David K, Perley, Daniel A, Ergon, Mattias, Gal-Yam, Avishay, Corsi, Alessandra, Andreoni, Igor, Barbarino, Cristina, Bellm, Eric C, Blagorodnova, Nadia, Bright, Joe S, Burns, E, Cenko, S Bradley, Cunningham, Virginia, De, Kishalay, Dekany, Richard, Dugas, Alison, Fender, Rob P, Fransson, Claes, Fremling, Christoffer, Goldstein, Adam, Graham, Matthew J, Hale, David, Horesh, Assaf, Hung, Tiara, Kasliwal, Mansi M, Kuin, N Paul M, Kulkarni, SR, Kupfer, Thomas, Lunnan, Ragnhild, Masci, Frank J, Ngeow, Chow-Choong, Nugent, Peter E, Ofek, Eran O, Patterson, Maria T, Petitpas, Glen, Rusholme, Ben, Sai, Hanna, Sfaradi, Itai, Shupe, David L, Sollerman, Jesper, Soumagnac, Maayane T, Tachibana, Yutaro, Taddia, Francesco, Walters, Richard, Wang, Xiaofeng, Yao, Yuhan, and Zhang, Xinhan
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Astronomical Sciences ,Physical Sciences ,Affordable and Clean Energy ,methods: observational ,shock waves ,stars: mass-loss ,supernovae: individual ,surveys ,astro-ph.HE ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) ,Astronomy & Astrophysics ,Astronomical sciences ,Particle and high energy physics ,Space sciences - Abstract
We present detailed observations of ZTF18abukavn (SN2018gep), discovered in high-cadence data from the Zwicky Transient Facility as a rapidly rising (1.4 ± 0.1 mag hr-1) and luminous (Mg,peak = -20 mag) transient. It is spectroscopically classified as a broad-lined stripped-envelope supernova (Ic-BL SN). The high peak luminosity (Lbol ≳ 3 × 1044 erg s-1), the short rise time (trise = 3 days in g band), and the blue colors at peak (g-r ∼ -0.4) all resemble the high-redshift Ic-BL iPTF16asu, as well as several other unclassified fast transients. The early discovery of SN2018gep (within an hour of shock breakout) enabled an intensive spectroscopic campaign, including the highest-temperature (Teff ≳ 40,000 K) spectra of a stripped-envelope SN. A retrospective search revealed luminous (Mg ∼ Mr ≈ mag) emission in the days to weeks before explosion, the first definitive detection of precursor emission for a Ic-BL. We find a limit on the isotropic gamma-ray energy release E γ,iso < 4.9 × 10 48 erg, a limit on X-ray emission LX < 1040 erg s-1, and a limit on radio emission ν Lν ≲ 1037 erg s-1. Taken together, we find that the early (< 10 days) data are best explained by shock breakout in a massive shell of dense circumstellar material (0.02 M⊙) at large radii (3 × 1014 cm) that was ejected in eruptive pre-explosion mass-loss episodes. The late-time (> 10 days) light curve requires an additional energy source, which could be the radioactive decay of Ni-56.
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- 2019
29. An ASKAP Search for a Radio Counterpart to the First High-significance Neutron Star–Black Hole Merger LIGO/Virgo S190814bv
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Dobie, Dougal, Stewart, Adam, Murphy, Tara, Lenc, Emil, Wang, Ziteng, Kaplan, David L, Andreoni, Igor, Banfield, Julie, Brown, Ian, Corsi, Alessandra, De, Kishalay, Goldstein, Daniel A, Hallinan, Gregg, Hotan, Aidan, Hotokezaka, Kenta, Jaodand, Amruta D, Karambelkar, Viraj, Kasliwal, Mansi M, McConnell, David, Mooley, Kunal, Moss, Vanessa A, Newman, Jeffrey A, Perley, Daniel A, Prakash, Abhishek, Pritchard, Joshua, Sadler, Elaine M, Sharma, Yashvi, Ward, Charlotte, Whiting, Matthew, and Zhou, Rongpu
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Astronomical Sciences ,Physical Sciences ,astro-ph.HE ,Astronomical and Space Sciences ,Astronomy & Astrophysics ,Astronomical sciences ,Space sciences - Abstract
We present results from a search for a radio transient associated with the LIGO/Virgo source S190814bv, a likely neutron star-black hole (NSBH) merger, with the Australian Square Kilometre Array Pathfinder. We imaged a 30 deg2 field at ΔT = 2, 9, and 33 days post-merger at a frequency of 944 MHz, comparing them to reference images from the Rapid ASKAP Continuum Survey observed 110 days prior to the event. Each epoch of our observations covers 89% of the LIGO/Virgo localization region. We conducted an untargeted search for radio transients in this field, resulting in 21 candidates. For one of these, AT2019osy, we performed multiwavelength follow-up and ultimately ruled out the association with S190814bv. All other candidates are likely unrelated variables, but we cannot conclusively rule them out. We discuss our results in the context of model predictions for radio emission from NSBH mergers and place constrains on the circum-merger density and inclination angle of the merger. This survey is simultaneously the first large-scale radio follow-up of an NSBH merger, and the most sensitive widefield radio transients search to-date.
- Published
- 2019
30. ZTF Early Observations of Type Ia Supernovae. I. Properties of the 2018 Sample
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Yao, Yuhan, Miller, Adam A, Kulkarni, SR, Bulla, Mattia, Masci, Frank J, Goldstein, Daniel A, Goobar, Ariel, Nugent, Peter, Dugas, Alison, Blagorodnova, Nadia, Neill, James D, Rigault, Mickael, Sollerman, Jesper, Nordin, J, Bellm, Eric C, Cenko, S Bradley, De, Kishalay, Dhawan, Suhail, Feindt, Ulrich, Fremling, C, Gatkine, Pradip, Graham, Matthew J, Graham, Melissa L, Ho, Anna YQ, Hung, T, Kasliwal, Mansi M, Kupfer, Thomas, Laher, Russ R, Perley, Daniel A, Rusholme, Ben, Shupe, David L, Soumagnac, Maayane T, Taggart, K, Walters, Richard, and Yan, Lin
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Space Sciences ,Physical Sciences ,Type Ia supernovae ,Sky surveys ,Catalogs ,Supernovae ,Surveys ,Photometry ,astro-ph.HE ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) ,Astronomy & Astrophysics ,Astronomical sciences ,Particle and high energy physics ,Space sciences - Abstract
Early-time observations of Type Ia supernovae (SNe Ia) are essential to constrain the properties of their progenitors. In this paper, we present high-quality light curves of 127 SNe Ia discovered by the Zwicky Transient Facility (ZTF) in 2018. We describe our method to perform forced point-spread function photometry, which can be applied to other types of extragalactic transients. With a planned cadence of six observations per night (three g + three r), all of the 127 SNe Ia are detected in both g and r bands more than 10 days (in the rest frame) prior to the epoch of g-band maximum light. The redshifts of these objects range from z = 0.0181 to 0.165; the median redshift is 0.074. Among the 127 SNe, 50 are detected at least 14 days prior to maximum light (in the rest frame), with a subset of nine objects being detected more than 17 days before g-band peak. This is the largest sample of young SNe Ia collected to date; it can be used to study the shape and color evolution of the rising light curves in unprecedented detail. We discuss six peculiar events in this sample: one 02cx-like event ZTF18abclfee (SN 2018crl), one Ia-CSM SN ZTF18aaykjei (SN 2018cxk), and four objects with possible super-Chandrasekhar mass progenitors: ZTF18abhpgje (SN 2018eul), ZTF18abdpvnd (SN 2018dvf), ZTF18aawpcel (SN 2018cir), and ZTF18abddmrf (SN 2018dsx).
- Published
- 2019
31. GROWTH on S190425z: Searching Thousands of Square Degrees to Identify an Optical or Infrared Counterpart to a Binary Neutron Star Merger with the Zwicky Transient Facility and Palomar Gattini-IR
- Author
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Coughlin, Michael W, Ahumada, Tomás, Anand, Shreya, De, Kishalay, Hankins, Matthew J, Kasliwal, Mansi M, Singer, Leo P, Bellm, Eric C, Andreoni, Igor, Cenko, S Bradley, Cooke, Jeff, Copperwheat, Christopher M, Dugas, Alison M, Jencson, Jacob E, Perley, Daniel A, Yu, Po-Chieh, Bhalerao, Varun, Kumar, Harsh, Bloom, Joshua S, Anupama, GC, Ashley, Michael CB, Bagdasaryan, Ashot, Biswas, Rahul, Buckley, David AH, Burdge, Kevin B, Cook, David O, Cromer, John, Cunningham, Virginia, D’Aì, Antonino, Dekany, Richard G, Delacroix, Alexandre, Dichiara, Simone, Duev, Dmitry A, Dutta, Anirban, Feeney, Michael, Frederick, Sara, Gatkine, Pradip, Ghosh, Shaon, Goldstein, Daniel A, Golkhou, V Zach, Goobar, Ariel, Graham, Matthew J, Hanayama, Hidekazu, Horiuchi, Takashi, Hung, Tiara, Jha, Saurabh W, Kong, Albert KH, Giomi, Matteo, Kaplan, David L, Karambelkar, VR, Kowalski, Marek, Kulkarni, Shrinivas R, Kupfer, Thomas, Masci, Frank J, Mazzali, Paolo, Moore, Anna M, Mogotsi, Moses, Neill, James D, Ngeow, Chow-Choong, Martínez-Palomera, Jorge, La Parola, Valentina, Pavana, M, Ofek, Eran O, Patil, Atharva Sunil, Riddle, Reed, Rigault, Mickael, Rusholme, Ben, Serabyn, Eugene, Shupe, David L, Sharma, Yashvi, Singh, Avinash, Sollerman, Jesper, Soon, Jamie, Staats, Kai, Taggart, Kirsty, Tan, Hanjie, Travouillon, Tony, Troja, Eleonora, Waratkar, Gaurav, and Yatsu, Yoichi
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Astronomical Sciences ,Physical Sciences ,Gravitational wave astronomy ,Transient detection ,Optical telescopes ,Astronomical and Space Sciences ,Astronomy & Astrophysics ,Astronomical sciences ,Space sciences - Abstract
The third observing run by LVC has brought the discovery of many compact binary coalescences. Following the detection of the first binary neutron star merger in this run (LIGO/Virgo S190425z), we performed a dedicated follow-up campaign with the Zwicky Transient Facility (ZTF) and Palomar Gattini-IR telescopes. The initial skymap of this single-detector gravitational wave (GW) trigger spanned most of the sky observable from Palomar Observatory. Covering 8000 deg2 of the initial skymap over the next two nights, corresponding to 46% integrated probability, ZTF system achieved a depth of ≈21 m AB in g-and r-bands. Palomar Gattini-IR covered 2200 square degrees in J-band to a depth of 15.5 mag, including 32% integrated probability based on the initial skymap. The revised skymap issued the following day reduced these numbers to 21% for the ZTF and 19% for Palomar Gattini-IR. We narrowed 338,646 ZTF transient "alerts" over the first two nights of observations to 15 candidate counterparts. Two candidates, ZTF19aarykkb and ZTF19aarzaod, were particularly compelling given that their location, distance, and age were consistent with the GW event, and their early optical light curves were photometrically consistent with that of kilonovae. These two candidates were spectroscopically classified as young core-collapse supernovae. The remaining candidates were ruled out as supernovae. Palomar Gattini-IR did not identify any viable candidates with multiple detections only after merger time. We demonstrate that even with single-detector GW events localized to thousands of square degrees, systematic kilonova discovery is feasible.
- Published
- 2019
32. Prediction of Survival After Implantation of a Fully Magnetically Levitated Left Ventricular Assist Device
- Author
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Mehra, Mandeep R., Nayak, Aditi, Morris, Alanna A., Lanfear, David E., Nemeh, Hassan, Desai, Sapna, Bansal, Aditya, Guerrero-Miranda, Cesar, Hall, Shelley, Cleveland, Joseph C., Jr., Goldstein, Daniel J., Uriel, Nir, Chen, Leway, Bailey, Stephen, Anyanwu, Anelechi, Heatley, Gerald, Chuang, Joyce, and Estep, Jerry D.
- Published
- 2022
- Full Text
- View/download PDF
33. How aging impacts vaccine efficacy: known molecular and cellular mechanisms and future directions
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Chen, Judy, Deng, Jane C., and Goldstein, Daniel R.
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- 2022
- Full Text
- View/download PDF
34. Age-induced prostaglandin E2 impairs mitochondrial fitness and increases mortality to influenza infection
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Chen, Judy, Deng, Jane C., Zemans, Rachel L., Bahmed, Karim, Kosmider, Beata, Zhang, Min, Peters-Golden, Marc, and Goldstein, Daniel R.
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- 2022
- Full Text
- View/download PDF
35. Changes in Food and Nutrient Intake and Diet Quality on a Low-Fat Vegan Diet Are Associated with Changes in Body Weight, Body Composition, and Insulin Sensitivity in Overweight Adults: A Randomized Clinical Trial
- Author
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Crosby, Lelia, Rembert, Emilie, Levin, Susan, Green, Amber, Ali, Zeeshan, Jardine, Meghan, Nguyen, Minh, Elliott, Patrick, Goldstein, Daniel, Freeman, Amber, Bradshaw, Meka, Holtz, Danielle N., Holubkov, Richard, Barnard, Neal D., and Kahleova, Hana
- Published
- 2022
- Full Text
- View/download PDF
36. GROWTH on S190510g: DECam Observation Planning and Follow-up of a Distant Binary Neutron Star Merger Candidate
- Author
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Andreoni, Igor, Goldstein, Daniel A, Anand, Shreya, Coughlin, Michael W, Singer, Leo P, Ahumada, Tomás, Medford, Michael, Kool, Erik C, Webb, Sara, Bulla, Mattia, Bloom, Joshua S, Kasliwal, Mansi M, Nugent, Peter E, Bagdasaryan, Ashot, Barnes, Jennifer, Cook, David O, Cooke, Jeff, Duev, Dmitry A, Fremling, U Christoffer, Gatkine, Pradip, Golkhou, V Zach, Kong, Albert KH, Mahabal, Ashish, Martínez-Palomera, Jorge, Tao, Duo, and Zhang, Keming
- Subjects
Astronomical Sciences ,Physical Sciences ,binaries: general ,gravitational waves ,methods: observational ,stars: neutron ,supernovae: general ,astro-ph.HE ,astro-ph.IM ,astro-ph.SR ,Astronomical and Space Sciences ,Astronomy & Astrophysics ,Astronomical sciences ,Space sciences - Abstract
The first two months of the third Advanced LIGO and Virgo observing run (2019 April-May) showed that distant gravitational-wave (GW) events can now be readily detected. Three candidate mergers containing neutron stars (NS) were reported in a span of 15 days, all likely located more than 100 Mpc away. However, distant events such as the three new NS mergers are likely to be coarsely localized, which highlights the importance of facilities and scheduling systems that enable deep observations over hundreds to thousands of square degrees to detect the electromagnetic counterparts. On 2019 May 10 02:59:39.292 UT the GW candidate S190510g was discovered and initially classified as a binary neutron star (BNS) merger with 98% probability. The GW event was localized within an area of 3462 deg2, later refined to 1166 deg2 (90%) at a distance of 227 92 Mpc. We triggered Target-of-Opportunity observations with the Dark Energy Camera (DECam), a wide-field optical imager mounted at the prime focus of the 4 m Blanco Telescope at Cerro Tololo Inter-American Observatory in Chile. This Letter describes our DECam observations and our real-time analysis results, focusing in particular on the design and implementation of the observing strategy. Within 24 hr of the merger time, we observed 65% of the total enclosed probability of the final skymap with an observing efficiency of 94%. We identified and publicly announced 13 candidate counterparts. S190510g was reclassified 1.7 days after the merger, after our observations were completed, with a "BNS merger" probability reduced from 98% to 42% in favor of a "terrestrial classification.
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- 2019
37. GROWTH on S190426c: Real-time Search for a Counterpart to the Probable Neutron Star–Black Hole Merger using an Automated Difference Imaging Pipeline for DECam
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Goldstein, Daniel A, Andreoni, Igor, Nugent, Peter E, Kasliwal, Mansi M, Coughlin, Michael W, Anand, Shreya, Bloom, Joshua S, Martínez-Palomera, Jorge, Zhang, Keming, Ahumada, Tomás, Bagdasaryan, Ashot, Cooke, Jeff, De, Kishalay, Duev, Dmitry A, Fremling, U Christoffer, Gatkine, Pradip, Graham, Matthew, Ofek, Eran O, Singer, Leo P, and Yan, Lin
- Subjects
Astronomical Sciences ,Physical Sciences ,gravitational waves ,stars: black holes ,stars: neutron ,surveys ,astro-ph.HE ,astro-ph.IM ,Astronomical and Space Sciences ,Astronomy & Astrophysics ,Astronomical sciences ,Space sciences - Abstract
The discovery of a transient kilonova following the gravitational-wave (GW) event GW170817 highlighted the critical need for coordinated rapid and wide-field observations, inference, and follow-up across the electromagnetic spectrum. In the southern hemisphere, the Dark Energy Camera (DECam) on the Blanco 4 m telescope is well suited to this task, as it is able to cover wide fields quickly while still achieving the depths required to find kilonovae like the one accompanying GW170817 to ∼500 Mpc, the binary neutron star (NS) horizon distance for current generation of LIGO/Virgo collaboration (LVC) interferometers. Here, as part of the multi-facility follow-up by the Global Relay of Observatories Watching Transients Happen collaboration, we describe the observations and automated data movement, data reduction, candidate discovery, and vetting pipeline of our target-of-opportunity DECam observations of S190426c, the first possible NS-black hole merger detected in GWs. Starting 7.5 hr after S190426c, over 11.28 hr of observations, we imaged an area of 525 deg2 (r band) and 437 deg2 (z band); this was 16.3% of the total original localization probability, and nearly all of the probability visible from the southern hemisphere. The machine-learning-based pipeline was optimized for fast turnaround, delivering transients for human vetting within 17 minutes, on average, of shutter closure. We reported nine promising counterpart candidates 2.5 hr before the end of our observations. One hour after our data-taking ended (roughly 20 hr after the announcement of S190426c), LVC released a refined skymap that reduced the probability coverage of our observations to 8.0%, demonstrating a critical need for localization updates on shorter (∼hour) timescales. Our observations yielded no detection of a bona fide counterpart to m z = 21.7 and m r = 22.2 at the 5σ level of significance, consistent with the refined LVC positioning. We view these observations and rapid inferencing as an important real-world test for this novel end-to-end wide-field pipeline.
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- 2019
38. Rates and Properties of Supernovae Strongly Gravitationally Lensed by Elliptical Galaxies in Time-domain Imaging Surveys
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Goldstein, Daniel A, Nugent, Peter E, and Goobar, Ariel
- Subjects
gravitational lensing: strong ,supernovae: general ,astro-ph.GA ,astro-ph.CO ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) ,Astronomy & Astrophysics - Abstract
Supernovae that are strongly gravitationally lensed (gLSNe) by elliptical galaxies are powerful probes of astrophysics and cosmology that will be discovered systematically by wide-field, high-cadence imaging surveys such as the Zwicky Transient Facility (ZTF) and the Large Synoptic Survey Telescope (LSST). Here we use pixel-level simulations that include observing strategy, target selection, supernova properties, and dust to forecast the rates and properties of gLSNe that ZTF and LSST will find. Applying the resolution-insensitive discovery strategy of Goldstein et al., we forecast that ZTF (LSST) can discover 0.02 (0.79) 91bg-like, 0.17 (5.92) 91T-like, 1.22 (47.84) Type Ia, 2.76 (88.51) Type IIP, 0.31 (12.78) Type IIL, and 0.36 (15.43) Type Ib/c gLSNe per year, with uncertainties dominated by uncertainties in the supernova rate. We also forecast that the surveys can discover at least 3.75 (209.32) Type IIn gLSNe per year, for a total of at least 8.60 (380.60) gLSNe per year under fiducial observing strategies. ZTF gLSNe have a median z s = 0.9, z l = 0.35, , Δt max = 10 days, min(θ) = 0.″25, and N img = 4. LSST gLSNe are less compact and less magnified, with a median z s = 1.0, z l = 0.4, , Δt max = 25 days, min(θ) = 0.″6, and N img = 2. We develop a model of the supernova-host galaxy connection and find that the vast majority of gLSN host galaxies will be multiply imaged, enabling detailed constraints on lens models with sufficiently deep high-resolution imaging taken after the supernova has faded. We release the results of our simulations as catalogs at http://portal.nersc.gov/project/astro250/glsne/.
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- 2019
39. The Zwicky Transient Facility: Science Objectives
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Graham, Matthew J, Kulkarni, SR, Bellm, Eric C, Adams, Scott M, Barbarino, Cristina, Blagorodnova, Nadejda, Bodewits, Dennis, Bolin, Bryce, Brady, Patrick R, Cenko, S Bradley, Chang, Chan-Kao, Coughlin, Michael W, De, Kishalay, Eadie, Gwendolyn, Farnham, Tony L, Feindt, Ulrich, Franckowiak, Anna, Fremling, Christoffer, Gezari, Suvi, Ghosh, Shaon, Goldstein, Daniel A, Golkhou, V Zach, Goobar, Ariel, Ho, Anna YQ, Huppenkothen, Daniela, Ivezić, Željko, Jones, R Lynne, Juric, Mario, Kaplan, David L, Kasliwal, Mansi M, Kelley, Michael SP, Kupfer, Thomas, Lee, Chien-De, Lin, Hsing Wen, Lunnan, Ragnhild, Mahabal, Ashish A, Miller, Adam A, Ngeow, Chow-Choong, Nugent, Peter, Ofek, Eran O, Prince, Thomas A, Rauch, Ludwig, van Roestel, Jan, Schulze, Steve, Singer, Leo P, Sollerman, Jesper, Taddia, Francesco, Yan, Lin, Ye, Quan-Zhi, Yu, Po-Chieh, Barlow, Tom, Bauer, James, Beck, Ron, Belicki, Justin, Biswas, Rahul, Brinnel, Valery, Brooke, Tim, Bue, Brian, Bulla, Mattia, Burruss, Rick, Connolly, Andrew, Cromer, John, Cunningham, Virginia, Dekany, Richard, Delacroix, Alex, Desai, Vandana, Duev, Dmitry A, Feeney, Michael, Flynn, David, Frederick, Sara, Gal-Yam, Avishay, Giomi, Matteo, Groom, Steven, Hacopians, Eugean, Hale, David, Helou, George, Henning, John, Hover, David, Hillenbrand, Lynne A, Howell, Justin, Hung, Tiara, Imel, David, Ip, Wing-Huen, Jackson, Edward, Kaspi, Shai, Kaye, Stephen, Kowalski, Marek, Kramer, Emily, Kuhn, Michael, Landry, Walter, Laher, Russ R, Mao, Peter, Masci, Frank J, Monkewitz, Serge, Murphy, Patrick, Nordin, Jakob, Patterson, Maria T, Penprase, Bryan, Porter, Michael, and Rebbapragada, Umaa
- Subjects
Astronomical Sciences ,Physical Sciences ,(stars:) supernovae: general ,surveys ,(galaxies:) quasars: general ,astro-ph.IM ,astro-ph.HE ,Astronomical and Space Sciences ,Astronomy & Astrophysics ,Astronomical sciences ,Particle and high energy physics - Abstract
The Zwicky Transient Facility (ZTF), a public–private enterprise, is a new time-domain survey employing a dedicated camera on the Palomar 48-inch Schmidt telescope with a 47 deg2 field of view and an 8 second readout time. It is well positioned in the development of time-domain astronomy, offering operations at 10% of the scale and style of the Large Synoptic Survey Telescope (LSST) with a single 1-m class survey telescope. The public surveys will cover the observable northern sky every three nights in g and r filters and the visible Galactic plane every night in g and r. Alerts generated by these surveys are sent in real time to brokers. A consortium of universities that provided funding (“partnership”) are undertaking several boutique surveys. The combination of these surveys producing one million alerts per night allows for exploration of transient and variable astrophysical phenomena brighter than r∼20.5 on timescales of minutes to years. We describe the primary science objectives driving ZTF, including the physics of supernovae and relativistic explosions, multi-messenger astrophysics, supernova cosmology, active galactic nuclei, and tidal disruption events, stellar variability, and solar system objects.
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- 2019
40. Single-object Imaging and Spectroscopy to Enhance Dark Energy Science from LSST
- Author
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Hložek, Renée A, Collett, Thomas, Galbany, Lluís, Goldstein, Daniel A, Jha, Saurabh W, Kim, Alex G, Mandelbaum, Rachel, Newman, Jeffrey A, Perlmutter, Saul, Perrefort, Daniel J, Sullivan, Mark, and Verma, Aprajita
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astro-ph.CO - Abstract
Single-object imaging and spectroscopy on telescopes with apertures rangingfrom ~4 m to 40 m have the potential to greatly enhance the cosmologicalconstraints that can be obtained from LSST. Two major cosmological probes willbenefit greatly from LSST follow-up: accurate spectrophotometry for nearby anddistant Type Ia supernovae will expand the cosmological distance lever arm byunlocking the constraining power of high-z supernovae; and cosmology with timedelays of strongly-lensed supernovae and quasars will require additionalhigh-cadence imaging to supplement LSST, adaptive optics imaging orspectroscopy for accurate lens and source positions, and IFU or slitspectroscopy to measure detailed properties of lens systems. We highlight thescientific impact of these two science drivers, and discuss how additionalresources will benefit them. For both science cases, LSST will deliver a largesample of objects over both the wide and deep fields in the LSST survey, butadditional data to characterize both individual systems and overall systematicswill be key to ensuring robust cosmological inference to high redshifts.Community access to large amounts of natural-seeing imaging on ~2-4 mtelescopes, adaptive optics imaging and spectroscopy on 8-40 m telescopes, andhigh-throughput single-target spectroscopy on 4-40 m telescopes will benecessary for LSST time domain cosmology to reach its full potential. In twocompanion white papers we present the additional gains for LSST cosmology thatwill come from deep and from wide-field multi-object spectroscopy.
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- 2019
41. The Zwicky Transient Facility: System Overview, Performance, and First Results
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Bellm, Eric C, Kulkarni, Shrinivas R, Graham, Matthew J, Dekany, Richard, Smith, Roger M, Riddle, Reed, Masci, Frank J, Helou, George, Prince, Thomas A, Adams, Scott M, Barbarino, C, Barlow, Tom, Bauer, James, Beck, Ron, Belicki, Justin, Biswas, Rahul, Blagorodnova, Nadejda, Bodewits, Dennis, Bolin, Bryce, Brinnel, Valery, Brooke, Tim, Bue, Brian, Bulla, Mattia, Burruss, Rick, Cenko, S Bradley, Chang, Chan-Kao, Connolly, Andrew, Coughlin, Michael, Cromer, John, Cunningham, Virginia, De, Kishalay, Delacroix, Alex, Desai, Vandana, Duev, Dmitry A, Eadie, Gwendolyn, Farnham, Tony L, Feeney, Michael, Feindt, Ulrich, Flynn, David, Franckowiak, Anna, Frederick, S, Fremling, C, Gal-Yam, Avishay, Gezari, Suvi, Giomi, Matteo, Goldstein, Daniel A, Golkhou, V Zach, Goobar, Ariel, Groom, Steven, Hacopians, Eugean, Hale, David, Henning, John, Ho, Anna YQ, Hover, David, Howell, Justin, Hung, Tiara, Huppenkothen, Daniela, Imel, David, Ip, Wing-Huen, Ivezić, Željko, Jackson, Edward, Jones, Lynne, Juric, Mario, Kasliwal, Mansi M, Kaspi, S, Kaye, Stephen, Kelley, Michael SP, Kowalski, Marek, Kramer, Emily, Kupfer, Thomas, Landry, Walter, Laher, Russ R, Lee, Chien-De, Lin, Hsing Wen, Lin, Zhong-Yi, Lunnan, Ragnhild, Mahabal, Ashish, Mao, Peter, Miller, Adam A, Monkewitz, Serge, Murphy, Patrick, Ngeow, Chow-Choong, Nordin, Jakob, Nugent, Peter, Ofek, Eran, Patterson, Maria T, Penprase, Bryan, Porter, Michael, Rauch, Ludwig, Rebbapragada, Umaa, Reiley, Dan, Rigault, Mickael, Rodriguez, Hector, van Roestel, Jan, Rusholme, Ben, van Santen, Jakob, Schulze, S, Shupe, David L, and Singer, Leo P
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Space Sciences ,Physical Sciences ,instrumentation: photometers ,telescopes ,astro-ph.IM ,Astronomical and Space Sciences ,Astronomy & Astrophysics ,Astronomical sciences ,Particle and high energy physics - Abstract
The Zwicky Transient Facility (ZTF) is a new optical time-domain survey that uses the Palomar 48 inch Schmidt telescope. A custom-built wide-field camera provides a 47 deg 2 field of view and 8 s readout time, yielding more than an order of magnitude improvement in survey speed relative to its predecessor survey, the Palomar Transient Factory. We describe the design and implementation of the camera and observing system. The ZTF data system at the Infrared Processing and Analysis Center provides near-real-time reduction to identify moving and varying objects. We outline the analysis pipelines, data products, and associated archive. Finally, we present on-sky performance analysis and first scientific results from commissioning and the early survey. ZTF’s public alert stream will serve as a useful precursor for that of the Large Synoptic Survey Telescope.
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- 2019
42. Characteristics and Outcomes of COVID-19 Patients Supported by Venoarterial or Veno-Arterial-Venous Extracorporeal Membrane Oxygenation
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Haroun, Magued W., Patel, Snehal R., Sims, Daniel B., Jorde, Ulrich P., Goldstein, Daniel J., and Saeed, Omar
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- 2022
- Full Text
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43. Center Variability in Patient Outcomes Following HeartMate 3 Implantation: An Analysis of the MOMENTUM 3 Trial
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Kanwar, MANREET K., PAGANI, FRANCIS D., MEHRA, MANDEEP R., ESTEP, JERRY D., PINNEY, SEAN P., SILVESTRY, SCOTT C., URIEL, NIR, GOLDSTEIN, DANIEL J., LONG, JAMES, CLEVELAND, JOSEPH C., JR., KORMOS, ROBERT L., WANG, AIJIA, CHUANG, JOYCE, and COWGER, JENNIFER A.
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- 2022
- Full Text
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44. Hospitalization Patterns and Impact of a Magnetically-Levitated Left Ventricular Assist Device in the MOMENTUM 3 Trial
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Vidula, Himabindu, Takeda, Koji, Estep, Jerry D., Silvestry, Scott C., Milano, Carmelo, Cleveland, Joseph C., Jr., Goldstein, Daniel J., Uriel, Nir, Kormos, Robert L., Dirckx, Nicholas, and Mehra, Mandeep R.
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- 2022
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45. Characteristics and outcomes of patients with COVID-19 supported by extracorporeal membrane oxygenation: A retrospective multicenter study
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Alvarez, Chikezie, DeAnda, Abe, Jr., Gluck, Jason, Jermyn, Rita, Kuntzman, Matthew, McKellar, Stephen, Parides, Michael K., Saunders, Paul, Saeed, Omar, Tatooles, Antone J., Farooq, Muhammad, Schwartz, Gary, Pham, Duc T., Mustafa, Asif K., D'Alessandro, David, Abrol, Sunil, Jorde, Ulrich P., Gregoric, Igor D., Radovancevic, Rajko, Lima, Brian, Bryner, Benjamin S., Ravichandran, Ashwin, Salerno, Christopher T., Spencer, Philip, Friedmann, Patricia, Silvestry, Scott, and Goldstein, Daniel J.
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- 2022
- Full Text
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46. Concordance of Treatment Effect: An Analysis of The Society of Thoracic Surgeons Intermacs Database
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Pagani, Francis D., Cantor, Ryan, Cowger, Jennifer, Goldstein, Daniel J., Teuteberg, Jeffrey J., Mahr, Claudius W., Atluri, Pavan, Kilic, Arman, Maozami, Nader, Habib, Robert H., Naftel, David, and Kirklin, James K.
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- 2022
- Full Text
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47. Rationale and design of a randomized trial evaluating an external support device for saphenous vein coronary grafts
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Bagiella, Emilia, Puskas, John D., Moskowitz, Alan J., Gelijns, Annetine C., Alexander, John H., Narula, Jagat, Smith, Peter K., Hutcheson, Kelley, Chang, Helena L., Gammie, James S., Iribarne, Alexander, Marks, Mary E., Vengrenyuk, Yuliya, Yasumura, Keisuke, Raymond, Samantha, Taylor, Bradley S., Yarden, Orit, Orion, Eyal, Dagenais, François, Ailawadi, Gorav, Chu, Michael W.A., Gupta, Lopa, Levitan, Ronald G., Williams, Judson B., Jr., Crestanello, Juan A., Jessup, Mariell, Rose, Eric A., Scavo, Vincent, Acker, Michael A., Gillinov, Marc, O'Gara, Patrick T., Voisine, Pierre, Mack, Michael J., and Goldstein, Daniel J.
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- 2022
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48. Combination therapy patents: a new front in evergreening
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Strohbehn, Garth W., Kacew, Alec J., Goldstein, Daniel A., Feldman, Robin C., and Ratain, Mark J.
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- 2021
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49. Feasibility and Potential Impact of Heart Transplantation From Adult Donors After Circulatory Death
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Madan, Shivank, Saeed, Omar, Forest, Stephen J., Goldstein, Daniel J., Jorde, Ulrich P., and Patel, Snehal R.
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- 2022
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50. Evaluating sex as a predictive marker for response to bevacizumab in metastatic colorectal carcinoma: Pooled analysis of 3,369 patients in the ARCAD database
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Margalit, Ofer, Harmsen, William S., Shacham-Shmueli, Einat, Voss, Molly M., Boursi, Ben, Wagner, Anna D., Cohen, Romain, Olswold, Curtis L., Saltz, Leonard B., Goldstein, Daniel A., Hurwitz, Herbert, Tebbutt, Niall C., Kabbinavar, Fairooz F., Adams, Richard A., Chibaudel, Benoist, Grothey, Axel, Yoshino, Takayuki, Zalcberg, John, de Gramont, Aimery, Shi, Qian, and Lenz, Heinz-Josef
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- 2022
- Full Text
- View/download PDF
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