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Copyright of MEDISAN is the property of Centro Provincial de Informacion en Ciencias Medicas de Santiago de Cuba and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The results of the exams that are carried out in the clinical laboratory should constitute an essential part in the evaluation of people included in clinical trials for the introduction of new medications. In this article the most important aspects of work in the laboratory are described, during the development of a trial where new technologies are used. Clinical trials not only improve health indicators of the population, but also, demand the best diagnosis standards and evaluation of the treatment, through new technologies, where clinical laboratory is included. [ABSTRACT FROM AUTHOR]

The internal control of quality in the clinical laboratory is a specialized activity that monitors the quality of the processes and results at the same time that it allows to accept or to reject the analytic runs on the different determinations. To such effects, the elements of a practical guide included in a software are presented, designed with the objective of perfecting the internal control of the quality in these laboratories, where the principles and key concepts of the topic, procedures and their sequence, requirements of quality, control rules, statistical calculations, the interpretation of the results are defined, as well as some of the novel and necessary indicators to assure the quality. [ABSTRACT FROM AUTHOR]

Copyright of MEDISAN is the property of Centro Provincial de Informacion en Ciencias Medicas de Santiago de Cuba and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A descriptive study of 205 users of the Central Laboratory of "Saturnino Lora Torres" Teaching Clinical Surgical Provincial Hospital in Santiago de Cuba was carried out from December, 2013 to the same period in 2014, in order to determine the reference levels of LDL cholesterol for the enzymatic method and identify estimates variations of analito according to 2 methodologies. Anderson Darling's parametric statistical test was applied. Male sex, young adult and the patients with normal weight prevailed. The reference values were established for LDL cholesterol by direct method from 1.37 to 4.89 mmol/L for the general population. A Pearson correlation coefficient of 0.82 was obtained between the direct method and the Friedewald formula. The obtained values were not contained in the established clinical range for this analito and although both methodologies were associated, such values were markedly inferior for the calculated method. [ABSTRACT FROM AUTHOR]