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1,541 results on '"Greiner W"'

2. New prospects in synthesis and study of neutron rich heavy nuclei

Author

Greiner W., Mishustin I.N., Karpov A.V., and Zagrebaev V.I.

Subjects
Physics, QC1-999
Abstract

The present limits of the upper part of the nuclear map are rather close to the beta stability line while the unexplored area of heavy neutron rich nuclides (also those located along the neutron closed shell N = 126 to the right hand side of the stability line) is extremely important for nuclear astrophysics investigations and, in particular, for the understanding of the r-process of astrophysical nucleogenesis. For elements with Z > 100 only neutron deficient isotopes (located to the left of the stability line) have been synthesized so far. The “north-east” area of the nuclear map can be reached neither in fusion–fission reactions nor in fragmentation processes widely used nowadays for the production of new nuclei. Multi-nucleon transfer processes in near barrier collisions of heavy ions seem to be the only reaction mechanism allowing us to produce and explore neutron rich heavy nuclei including those located at the superheavy island of stability. Neutron capture process can be also considered as an alternative method for the production of long-lived neutron rich superheavy nuclei. Strong neutron fluxes might be provided by nuclear reactors and nuclear explosions in laboratory frame and by supernova explosions in nature.

Published
2011
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27. SALUS—a non-inferiority trial to compare self-tonometry in glaucoma patients with regular inpatient intraocular pressure controls: study design and set-up.

Author

Oldiges, Kristina, Steinmann, Maren, Duevel, Juliane Andrea, Gruhn, Sebastian, Diener, Raphael, Leclaire, Martin Dominik, Al-Nawaiseh, Sami, Eter, Nicole, on behalf of the SALUS study group, Greiner, W., Behm, B., Kisielinski, D., Schwarze, K., Meyer, F., Warkentin, S., Hammerschmidt, R., Luzius, M., Berlage, T., Becker, M., and Charles, A.

Subjects
INTRAOCULAR pressure, PRESSURE control, GLAUCOMA, EXPERIMENTAL design, HEALTH literacy, CLINICAL trials monitoring
Abstract

Purpose: The SALUS study aims to improve the healthcare situation for glaucoma patients in Germany. In order to detect diurnal intraocular pressure (IOP) fluctuations, inpatient monitoring of IOP in an eye hospital for a minimum of 24 h is the current standard. SALUS assesses the benefits of a new form of outpatient care, where IOP can be measured by the patients themselves at home using a self-tonometer. This approach should promote the patient's health competence and empowerment within the healthcare system while reducing treatment costs. Methods: The SALUS study is a randomized controlled, open non-inferiority trial, alongside an economic analysis, determining whether outpatient monitoring of IOP with self-tonometry is at least as effective as current standard care and would reduce treatment costs. Participants (n = 1980) will be recruited by local ophthalmologists in the area of Westphalia-Lippe, Germany, and randomized to receive 7-day outpatient or 24-h inpatient monitoring. Participants in both study arms will also receive 24-h blood pressure monitoring. Furthermore, patient data from both study groups will be collected in an electronic case file (ECF), accessible to practitioners, hospitals, and the study participants. The primary endpoint is the percentage of patients with IOP peaks, defined as levels 30% above the patient-specific target pressure. Data will also be collected during initial and final examinations, and at 3, 6, and 9 months after the initial examination. Results: The study implementation and trial management are represented below. Conclusion: SALUS is a pioneering prospective clinical trial focused on the care of glaucoma patients in Germany. If SALUS is successful, it could improve the healthcare situation and health literacy of the patients through the introduction of various telemedical components. Furthermore, the approach would almost certainly reduce the treatment costs of glaucoma care. Trial registration: ClinicalTrials.gov ID: NCT04698876, registration date: 11/25/2020. DRKS-ID: DRKS00023676, registration date: 11/26/2020. [ABSTRACT FROM AUTHOR]

Published
2022
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37. Voraussetzungen für ein neues Versorgungsmodell für ältere Menschen mit Multimorbidität: Ergebnisse und Schlussfolgerungen aus 3-jähriger Forschung im PRISCUS-Verbund

Author

Thiem*, U., Hinrichs*, T., Müller*, C.A., Holt-Noreiks*, S., Nagl*, A., Bucchi, C., Trampisch, U., Moschny, A., Platen, P., Penner, E., Junius-Walker, U., Hummers-Pradier, E., Theile, G., Schmiedl, S., Thürmann, P.A., Scholz, S., Greiner, W., Klaaßen-Mielke, R., Pientka, L., and Trampisch, H.J.

Published
2011
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