686 results on '"He, Qiaojun"'
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2. Regorafenib inhibits EphA2 phosphorylation and leads to liver damage via the ERK/MDM2/p53 axis
3. Dabrafenib alleviates hepatotoxicity caused by lenvatinib via inhibiting the death receptor signaling pathway
4. Targeting the Wnt/β-catenin signal pathway for the treatment of gastrointestinal cancer: Potential for advancement
5. Macrophage senescence in health and diseases
6. Insights into the role of derailed endocytic trafficking pathway in cancer: From the perspective of cancer hallmarks
7. Cediranib enhances the transcription of MHC-I by upregulating IRF-1
8. Development and safety of PI3K inhibitors in cancer
9. Cancer-associated fibroblasts drive early pancreatic cancer cell invasion via the SOX4/MMP11 signalling axis
10. Unraveling the treatment effects of huanglian jiedu decoction on drug-induced liver injury based on network pharmacology, molecular docking and experimental validation
11. Rutin attenuates ensartinib-induced hepatotoxicity by non-transcriptional regulation of TXNIP
12. Josephin domain containing 2 (JOSD2) promotes lung cancer by inhibiting LKB1 (Liver kinase B1) activity
13. Strategies to synergize PD-1/PD-L1 targeted cancer immunotherapies to enhance antitumor responses in ovarian cancer
14. Crizotinib induces pulmonary toxicity by blocking autophagy flux in alveolar epithelial cells
15. The palmitoyltransferase ZDHHC21 regulates oxidative phosphorylation to induce differentiation block and stemness in AML
16. Mevalonate improves anti-PD-1/PD-L1 efficacy by stabilizing CD274 mRNA
17. Opportunities and challenges of incretin-based hypoglycemic agents treating type 2 diabetes mellitus from the perspective of physiological disposition
18. A practical “preTACs-cytoblot” platform accelerates the streamlined development of PROTAC-based protein degraders
19. Fingolimod exerts in vitro anticancer activity against hepatocellular carcinoma cell lines via YAP/TAZ suppression
20. Dasatinib causes keratinocyte apoptosis via inhibiting high mobility group Box 1-mediated mitophagy
21. Deubiquitination complex platform: A plausible mechanism for regulating the substrate specificity of deubiquitinating enzymes
22. Butein suppresses PD-L1 expression via downregulating STAT1 in non-small cell lung cancer
23. Structures of the endogenous peptide- and selective non-peptide agonist-bound SSTR2 signaling complexes
24. Deneddylation of PML/RARα reconstructs functional PML nuclear bodies via orchestrating phase separation to eradicate APL
25. CT-707 overcomes hypoxia-mediated sorafenib resistance in Hepatocellular carcinoma by inhibiting YAP signaling
26. Design, synthesis and biological evaluation of new dihydropyridine derivatives as PD-L1 degraders for enhancing antitumor immunity
27. Protective effects of six different pectic polysaccharides on DSS-induced IBD in mice
28. Design, synthesis, and biological evaluation of quinazoline derivatives with covalent reversible warheads as potential FGFR4 inhibitors
29. Noncovalent CDK12/13 dual inhibitors-based PROTACs degrade CDK12-Cyclin K complex and induce synthetic lethality with PARP inhibitor
30. Multi-constraint molecular generation based on conditional transformer, knowledge distillation and reinforcement learning
31. Design, synthesis and biological evaluation of quinazoline derivatives as potent and selective FGFR4 inhibitors
32. Bisdemethoxycurcumin alleviates vandetanib-induced cutaneous toxicity in vivo and in vitro through autophagy activation
33. Anti-inflammation effects of highly purified low-Mw RG-I pectins on LPS-activated macrophages
34. Defining therapeutic targets for renal fibrosis: Exploiting the biology of pathogenesis
35. Cyclin-dependent kinases-based synthetic lethality: Evidence, concept, and strategy
36. Canagliflozin primes antitumor immunity by triggering PD-L1 degradation in endocytic recycling
37. Recent advance of peptide-based molecules and nonpeptidic small-molecules modulating PD-1/PD-L1 protein-protein interaction or targeting PD-L1 protein degradation
38. Crosstalk between alveolar macrophages and alveolar epithelial cells/fibroblasts contributes to the pulmonary toxicity of gefitinib
39. Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy
40. Effects of prepubertal exposure to forchlorfenuron through prenatal and postnatal gavage administration in developing Sprague-Dawley rats
41. Structure-activity relationship of Citrus segment membrane RG-I pectin against Galectin-3: The galactan is not the only important factor
42. PD-1/PD-L1 counterattack alliance: multiple strategies for treating triple-negative breast cancer
43. CovEpiAb: a comprehensive database and analysis resource for immune epitopes and antibodies of human coronaviruses.
44. SynergyX: a multi-modality mutual attention network for interpretable drug synergy prediction.
45. Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling
46. ASFP (Artificial Intelligence based Scoring Function Platform): a web server for the development of customized scoring functions
47. Targeting post-translational modification of transcription factors as cancer therapy
48. Advances in differentiation therapy for osteosarcoma
49. Keratinocytes apoptosis contributes to crizotinib induced-erythroderma
50. s-HBEGF/SIRT1 circuit-dictated crosstalk between vascular endothelial cells and keratinocytes mediates sorafenib-induced hand–foot skin reaction that can be reversed by nicotinamide
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