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197 results on '"Hellinga, Homme W."'

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17. Retraction

26. Rational design of a calcium-binding protein

27. Computational design of receptor and sensor proteins with novel functions

29. Converting a maltose receptor into a nascent binuclear copper oxygenase by computational design

36. Construction of a Blue Copper analogue through iterative rational protein design cycles demonstrates principles of molecular recognition in metal center formation

37. Construction of a family of Cys2His2 zinc binding sites in the hydrophobic core of thioredoxin by structure-based design

38. Construction of a novel redox protein by rational design: conversion of a disulfide bridge into a mononuclear iron-sulfur center

39. Engineering biosensors by introducing fluorescent allosteric ssignal transducers: construction of a novel glucose sensor

44. Mapping staphylococcal nuclease conformation using an EDTA-Fe derivative attached to genetically engineered cysteine residues

45. Thermodynamic effects of reduction of the active-site disulfide of Escherichia coli thioredoxin explored by differential scanning calorimetry

46. Stability of oxidized Escherichia coli thioredoxin and its dependence on protonation of the aspartic acid residue in the 26 position

49. Thermodynamic analysis of ligand-induced changes in protein thermal unfolding applied to high-throughput determination of ligand affinities with extrinsic fluorescent dyes

50. Structural reorganization and preorganization in enzyme active sites: comparisons of experimental and theoretically ideal active site geometries in the multistep serine esterase reaction cycle

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