1. Late-Onset Neutropenia after Rituximab Treatment for Adult-Onset Nephrotic Syndrome
- Author
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Mayuko Yamazaki, Hidekazu Sugiura, Yosuke Iwatani, Mizuki Kyoda, Hirohiko Nokiba, Nobuyuki Amemiya, Kosaku Nitta, and Ken Tsuchiya
- Subjects
Diseases of the genitourinary system. Urology ,RC870-923 - Abstract
A 41-year-old woman developed nephrotic syndrome at the age of 32 and was diagnosed with minimal change nephrotic syndrome based on a renal biopsy. Although remission was achieved with administration of prednisolone (PSL) and cyclosporine, the nephrotic syndrome recurred. She was also started on rituximab (RTX). She developed late-onset neutropenia after RTX treatment (R-LON) and improved 17 days later. Although the majority of R-LON cases undergo spontaneous remission, cases of death have been reported. This report is intended to warn about R-LON, since the use of RTX for adult-onset nephrotic syndrome is expected to increase in the future.
- Published
- 2019
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