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Your search keyword '"Katharina Angerer"' showing total 1 results
Start Over Author "Katharina Angerer" Publication Type Academic Journals
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1. A modular self-adjuvanting cancer vaccine combined with an oncolytic vaccine induces potent antitumor immunity

Author

Krishna Das, Elodie Belnoue, Matteo Rossi, Tamara Hofer, Sarah Danklmaier, Tobias Nolden, Liesa-Marie Schreiber, Katharina Angerer, Janine Kimpel, Sandra Hoegler, Bart Spiesschaert, Lukas Kenner, Dorothee von Laer, Knut Elbers, Madiha Derouazi, and Guido Wollmann

Subjects
Science
Abstract

Successful cancer immune therapy correlates with a T cell-inflamed tumour microenvironment. Authors show here that co-administration of a self-adjuvanting protein vaccine and an antigen-expressing oncolytic virus in an optimised regimen strongly enhances T cell immunogenicity and may turn non-inflamed tumours proinflammatory and less resistant to checkpoint blockade therapy.

Published
2021
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