302 results on '"Krishnamurthy, Sairam"'
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2. Inhibition of phosphodiesterase-4 mitigates stress-re-stress-paradigm induced mitochondrial perturbations in rats exhibiting PTSD-like symptoms
3. Diet and Nutraceuticals for treatment and prevention of primary and secondary stroke: Emphasis on nutritional antiplatelet and antithrombotic agents
4. Rhodanine composite fluorescence probes to detect pathological hallmarks in Alzheimer's disease models
5. Centella asiatica improves memory and executive function in middle-aged rats by controlling oxidative stress and cholinergic transmission
6. Lead optimization based design, synthesis, and pharmacological evaluation of quinazoline derivatives as multi-targeting agents for Alzheimer's disease treatment
7. Design, synthesis, and biological evaluation of some 2-(3-oxo-5,6-diphenyl-1,2,4-triazin-2(3H)-yl)-N-phenylacetamide hybrids as MTDLs for Alzheimer's disease therapy
8. Suvorexant improves mitochondrial dynamics with the regulation of orexinergic and mTOR activation in rats exhibiting PTSD-like symptoms
9. Preparation, Characterization, in-vitro and in-vivo Pharmacokinetic Evaluation of Thermostable Dimethyl Fumarate Cocrystals
10. Development of multi-targetable chalcone derivatives bearing N-aryl piperazine moiety for the treatment of Alzheimer's disease
11. Discovery of triazole-bridged aryl adamantane analogs as an intriguing class of multifunctional agents for treatment of Alzheimer's disease
12. Indole-3-carbinol ameliorated the thioacetamide-induced hepatic encephalopathy in rats
13. Vasicinone, a pyrroloquinazoline alkaloid from Adhatoda vasica Nees enhances memory and cognition by inhibiting cholinesterases in Alzheimer's disease
14. Discovery of multi-target directed 3-OH pyrrolidine derivatives through a semisynthetic approach from alkaloid vasicine for the treatment of Alzheimer's disease
15. Identification of novel glucocerebrosidase chaperone for potential treatment of Parkinson's disease: An approach using in silico virtual screening, molecular docking and molecular dynamics, and in vitro studies
16. Effects of ELF-PEMF exposure on spontaneous alternation, anxiety, motor co-ordination and locomotor activity of adult wistar rats and viability of C6 (Glial) cells in culture
17. Standardization and validation of novel ex-vivo method for mitochondrial bioenergetics using mitochondrial modulators
18. Pharmacokinetic and Pharmacodynamic Properties of Indole-3-carbinol in Experimental Focal Ischemic Injury
19. In vivo toxicological evaluation of barium-doped bioactive glass in rats
20. An in vivo toxicity assessment of piezoelectric sodium potassium niobate [NaxK1-xNbO3 (x = 0.2–0.8)] nanoparticulates towards bone tissue engineering approach
21. Generation of wild-type rat Glucocerebrosidase homology modeling: Identification of putative interactions site and mechanism for chaperone using combined in-silico and in-vitro studies
22. Diindolylmethane ameliorates platelet aggregation and thrombosis: In silico, in vitro, and in vivo studies
23. Mitochondrial dysfunction in perinatal asphyxia: role in pathogenesis and potential therapeutic interventions
24. Dihydroquercetin ameliorates LPS-induced neuroinflammation and memory deficit
25. Bioactive glass: A multifunctional delivery system
26. In-vitro analysis of bioactivity, hemolysis, and mechanical properties of Zn substituted Calcium Zirconium silicate (baghdadite)
27. Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer’s action: Design, synthesis, crystal structure and in-vitro biological evaluation
28. Synthesis and characterization of barium-doped bioactive glass with potential anti-inflammatory activity
29. Development and treatment of cognitive inflexibility in sub-chronic stress–re-stress (SRS) model of PTSD
30. Design and development of molecular hybrids of 2-pyridylpiperazine and 5-phenyl-1,3,4-oxadiazoles as potential multifunctional agents to treat Alzheimer's disease
31. Discovery of novel series of 2-substituted benzo[d]oxazol-5-amine derivatives as multi-target directed ligands for the treatment of Alzheimer's disease
32. Neurorestorative effects of sub-chronic administration of ambroxol in rodent model of Parkinson’s disease
33. Neurochemical Evidence of Preclinical and Clinical Reports on Target-Based Therapy in Alcohol Used Disorder
34. Neuroprotective effect of chlorogenic acid in global cerebral ischemia-reperfusion rat model
35. Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease
36. Pharmacological application of barium containing bioactive glass in gastro-duodenal ulcers
37. Oral Release Kinetics, Biodistribution, and Excretion of Dopants from Barium-Containing Bioactive Glass in Rats.
38. Development of Piperazinediones as dual inhibitor for treatment of Alzheimer's disease
39. Enhanced in vivo biocompatibility of magnesia-contained bioactive glasses
40. Preparation and in vitro investigation on bioactivity of magnesia-contained bioactive glasses
41. 2,4 Dinitrophenol Attenuates Mitochondrial Dysfunction and Improves Neurobehavioral Outcomes Postanoxia in Neonatal Rats
42. Electromagnetic radiation 2450 MHz exposure causes cognition deficit with mitochondrial dysfunction and activation of intrinsic pathway of apoptosis in rats
43. Indole-3-carbinol improves neurobehavioral symptoms in a cerebral ischemic stroke model
44. Pharmacokinetic Study of Piracetam in Focal Cerebral Ischemic Rats
45. Novel Gastroprotective and Thermostable Cocrystal of Dimethyl Fumarate: Its Preparation, Characterization, and In Vitro and In Vivo Evaluation.
46. Chronic exposure to dim artificial light disrupts the daily rhythm in mitochondrial respiration in mouse suprachiasmatic nucleus.
47. Design, Synthesis, and Biological Evaluation of Piperazine and N‑Benzylpiperidine Hybrids of 5‑Phenyl-1,3,4-oxadiazol-2-thiol as Potential Multitargeted Ligands for Alzheimer's Disease Therapy.
48. Purinergic Antagonism Prevents Mitochondrial Dysfunction and Behavioral Deficits Associated with Dopaminergic Toxicity Induced by 6-OHDA in Rats
49. Coenzyme Q10 Prevents Mitochondrial Dysfunction and Facilitates Pharmacological Activity of Atorvastatin in 6-OHDA Induced Dopaminergic Toxicity in Rats
50. Piracetam Attenuates LPS-Induced Neuroinflammation and Cognitive Impairment in Rats
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