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Start Over Author "Müller, Michael" Publication Type Academic Journals
3,163 results on '"Müller, Michael"'

5. Risk assessment of mixed and displacement ventilation (LAF) during orthopedic and trauma surgery on COVID-19 patients with increased release of infectious aerosols

Author

Kramer, Axel, Külpmann, Rüdiger, Brunner, Arnold, Müller, Michael, and Wassilew, Georgi

Subjects
displacement ventilation, laminar air flow, mixed ventilation, no ventilation, negative pressure, sars-cov-2 spread, Medicine, Public aspects of medicine, RA1-1270, Microbiology, QR1-502
Published
2020
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6. Hybrid-DRGs – Die Herausforderung

Author

Kisch, Tobias, Müller-Rath, Ralf, Gregor, Sven, Lorenz, Ralph, Neumann, Axel, Dittrich, Stephan, Müller, Michael, Lippert, Ralf, Henniger, Jan, Lembeck, Burkhard, Baur, Eva-Maria, Karst, Jörg, Vescia, Frank, and Schmitz, Ralf

Published
2024
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7. Retinitis bei Rickettsiose

Author

Biller, Marvin Lucas, Kaiser, Klemens Paul, Kessel, Johanna, Koepsell, Julia, Besier, Silke, Kenikstul, Ninel, Bucur, Julian, Müller, Michael, and Kohnen, Thomas

Published
2024
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8. Differences between women and men in prolonged weaning

Author

Röser, Evelyn, Michels-Zetsche, Julia D., Ersöz, Hilal, Neetz, Benjamin, Höger, Philipp, Trinkmann, Frederik, Müller, Michael M., Klotz, Laura, Kontogianni, Konstantina, Winter, Hauke, Dahlhoff, Jana Christina, Krysa, Sabine, Herth, Felix J. F., and Trudzinski, Franziska C.

Published
2024
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9. E-learning—an interventional element of the PRiVENT project to improve weaning expertise

Author

Michels-Zetsche, Julia D., Schubert-Haack, Janina, Tanck, Katrin, Neetz, Benjamin, Iberl, Gabriele, Müller, Michael, Kempa, Axel, Joves, Biljana, Rheinhold, Andreas, Ghiani, Alessandro, Tsitouras, Konstantinos, Schneider, Armin, Rauch, Christoph, Gehrig, Patrick, Biehler, Elena, Fleischauer, Thomas, Britsch, Simone, Frerk, Timm, Szecsenyi, Joachim, Herth, Felix J. F., and Trudzinski, Franziska C.

Published
2024
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18. A ketogenic diet in combination with gemcitabine increases survival in pancreatic cancer KPC mice

Author

Cortez, Natalia E, Lanzi, Cecilia Rodriguez, Hong, Brian V, Xu, Jihao, Wang, Fangyi, Chen, Shuai, Ramsey, Jon J, Pontifex, Matthew G, Müller, Michael, Vauzour, David, Vahmani, Payam, Hwang, Chang-Il, Matsukuma, Karen, and Mackenzie, Gerardo G

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Rare Diseases, Complementary and Integrative Health, Digestive Diseases, Pancreatic Cancer, Cancer, Nutrition, Mice, Male, Female, Animals, Gemcitabine, Diet, Ketogenic, Pancreatic Neoplasms, Carcinoma, Pancreatic Ductal, ERK and AKT signaling pathways, Ketogenic diet, Lipid metabolism, gemcitabine, microbiome, pancreatic cancer, pancreatic ductal adenocarcinoma
Abstract

Pancreatic ductal adenocarcinoma (PDAC) continues to be a major health problem. A ketogenic diet (KD), characterized by a very low carbohydrate and high fat composition, has gained attention for its anti-tumor potential. We evaluated the effect and mechanisms of feeding a strict KD alone or in combination with gemcitabine in the autochthonous LSL-KrasG12D/+; LSL-Trp53 R172H/+; Pdx1-Cre (KPC) mouse model. For this purpose, both male and female pancreatic tumor-bearing KPC mice were allocated to a control diet (CD; %kcal: 70% carb, 14% protein, 16% fat), a KD (%kcal: 14% protein, 1% carb, 85% fat), a CD + gemcitabine (CG), or a KD + gemcitabine (KG) group. Mice fed a KD alone or in combination with gemcitabine showed significantly increased blood β-hydroxybutyrate levels compared to mice fed a CD or CG. KPC mice fed a KG had a significant increase in overall median survival compared to KPC mice fed a CD (increased overall median survival by 42%). Interestingly, when the data was disaggregated by sex, the effect of a KG was significant in female KPC mice (60% increase in median overall survival), but not in male KPC mice (28% increase in median overall survival). Mechanistically, the enhanced survival response to a KD combined with gemcitabine was multifactorial, including inhibition of ERK and AKT pathways, regulation of fatty acid metabolism and the modulation of the gut microbiota. In summary, a KD in combination with gemcitabine appears beneficial as a treatment strategy in PDAC in KPC mice, deserving further clinical evaluation.

Published
2022

23. Digitales Notfallmanagement im Netzwerk der Akut- und Notfallversorgung. Eckpunktepapier des Expertenrats des ZTM

Author

Eder, Patrick Andreas, Soda, Hassan, Kumle, Bernhard, Dodt, Christoph, Dormann, Harald, Popp, Erik, Flasch, Bernhard, Müller, Michael Patrick, Böhmer, Matthias, Kerber, Sebastian, Barth, Sebastian, Krämer, Rainer, Kraus, Martin, Purrucker, Jan C., Oberhoff, Martin, Hans, Felix P., Stäblein, Heiko, Brammen, Dominik, Gilmore, Scott, Deneke, Thomas, Wehler, Markus, and Rashid, Asarnusch

Published
2023
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27. The impact of Substantial LYMphovascular space invasion on sentinel lymph nodes status and recurrence in Endometrial Cancer patients: SLYM-EC a multicenter retrospective study

Author

Buda, Alessandro, Fruscio, Robert, Mauro, Jessica, Imboden, Sara, De Ponti, Elena, Perrone, Emanuele, Grassi, Tommaso, Bruno, Valentina, Garcia-Pineda, Virginia, Taskin, Salih, Restaino, Stefano, Siegenthaler, Franziska, Casarin, Jvan, Raimondo, Diego, Capozzi, Vito Andrea, Vatansever, Dogan, Capasso, Ilaria, Vizza, Enrico, Gungor, Mete, Zapardiel, Ignacio, Papadia, Andrea, Taskiran, Cagatay, Fanfani, Francesco, Vizzielli, Giuseppe, Scambia, Giovanni, and Mueller, Michael

Published
2024
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30. Standalone Axial Malrotation after Pediatric Supracondylar Fracture Does Not Seem to Be an Indication for Immediate Postoperative Revision Surgery.

Author

Greve, Frederik, Müller, Michael, Wurm, Markus, Biberthaler, Peter, Singer, Georg, Till, Holger, and Wegmann, Helmut

Subjects
axial malrotation, long-term outcome, pediatric supracondylar humeral fracture, rotational spur
Abstract

Rotational spurs as evidence for post-surgical malrotation are frequently observed when treating pediatric supracondylar humeral fractures (SCHFs). This study aimed to investigate the long-term outcome of a pediatric cohort with unrevised axial malrotation and to discuss the indication for revision surgery. Postoperative radiographs of children treated for SCHFs over eight years were retrospectively analyzed. Children with radiological signs of malrotation (von Laer malrotation quotient) were invited for a follow-up clinical and radiological examination. Among 338 treated children, 39 (11.5%) with a mean age of 5.3 years (range 1.8-11.7 years) showed radiological signs for postoperative malrotation and were not revised and therefore invited to participate in the study. Twelve patients (31%) with a mean age of 11.3 years (range 8.8-13.8 years) took part in the follow-up examination after a mean of 7.1 years (range 5.4 to 11.3 years). The mean postoperative van Laer malrotation quotient was 0.15 (range 0.11-0.2). At follow-up, the range of motion of the elbow joint was not significantly different compared to the contralateral side. Apart from the humeral ulnar angle (p = 0.023), there were no significant differences in the radiological axes. The Flynn criteria were excellent and good in 90% of the cases. The mean was 1.7 points indicating excellent subjective results. Standalone postoperative malrotation did not lead to an adverse long-term outcome in a small cohort of pediatric patients with SCHFs and did not indicate immediate postoperative revision surgery. However, further investigations with larger cohorts should verify whether additional criteria such as stability of the osteosynthesis and signs for increasing valgus or varus displacement in the follow-up radiographs should get more importance in decision making.

Published
2022

38. Prevention of invasive ventilation (PRiVENT)—a prospective, mixed-methods interventional, multicentre study with a parallel comparison group: study protocol

Author

Michels, Julia D., Meis, Jan, Sturm, Noemi, Bornitz, Florian, von Schumann, Selina, Weis, Aline, Neetz, Benjamin, Bentner, Martina, Forstner, Johanna, Litke, Nicola, Wensing, Michel, Erdmann, Stella, Grobe, Thomas, Frerk, Timm, Kempa, Axel, Neurohr, Claus, Schneider, Armin, Müller, Michael, Herth, Felix J. F., Szecsenyi, Joachim, and Trudzinski, Franziska C.

Published
2023
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39. Creating World Views: Work-Expenditure Calculations for Funnel Beaker Megalithic Graves and Flint Axe Head Depositions in Northern Germany

Author

Wunderlich Maria, Müller Michael, and Behrens Anja

Subjects
collective action, neolithic monumentality, megalithic architecture, neolithic ritual practices, work expenditure, Archaeology, CC1-960
Abstract

The creation, maintenance, and modification of prehistoric built spaces and structural landscapes required communities that engaged and interacted collectively. Starting from the appearance of early monumentality and depositional behaviour in Funnel Beaker communities, we trace the variation in this phenomenon among three study areas in what is now northern Germany. In doing so, we build on a specific perspective and approach, namely that of work-expenditure calculations for megalithic graves and flint axe heads. In the process, variable dynamics of construction and deposition activities within the Early and Middle Neolithic are revealed, which we regard as differentiated translations of widespread impulses, adapted to the needs of different socio-cultural communities. The similar developments seen in flint axe head depositions and in the construction of megalithic monuments are indicative of evolving spaces of memory, landscapes of cooperative collaboration, and an increasing structuring of local environments that seem to follow a specific understanding of, and interaction with, space.

Published
2024
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46. Sex, Genotype, and Liver Volume Progression as Risk of Hospitalization Determinants in Autosomal Dominant Polycystic Liver Disease

Author

Ambrose, John C., Arumugam, Prabhu, Bevers, Roel, Bleda, Marta, Boardman-Pretty, Freya, Boustred, Christopher R., Brittain, Helen, Caulfield, Mark J., Chan, Georgia C., Elgar, Greg, Fowler, Tom, Giess, Adam, Hamblin, Angela, Henderson, Shirley, Hubbard, Tim J.P., Jackson, Rob, Jones, Louise J., Kasperaviciute, Dalia, Kayikci, Melis, Kousathanas, Athanasios, Lahnstein, Lea, Leigh, Sarah E.A., Leong, Ivonne U.S., Lopez, Javier F., Maleady-Crowe, Fiona, McEntagart, Meriel, Minneci, Federico, Moutsianas, Loukas, Mueller, Michael, Murugaesu, Nirupa, Need, Anna C., O’Donovan, Peter, Odhams, Chris A., Patch, Christine, Pereira, Mariana Buongermino, Perez-Gil, Daniel, Pullinger, John, Rahim, Tahrima, Rendon, Augusto, Rogers, Tim, Savage, Kevin, Sawant, Kushmita, Scott, Richard H., Siddiq, Afshan, Sieghart, Alexander, Smith, Samuel C., Sosinsky, Alona, Stuckey, Alexander, Tanguy, Mélanie, Taylor Tavares, Ana Lisa, Thomas, Ellen R.A., Thompson, Simon R., Tucci, Arianna, Welland, Matthew J., Williams, Eleanor, Witkowska, Katarzyna, Wood, Suzanne M., Schönauer, Ria, Sierks, Dana, Boerrigter, Melissa, Jawaid, Tabinda, Caroff, Lea, Audrezet, Marie-Pierre, Friedrich, Anja, Shaw, Melissa, Degenhardt, Jan, Forberger, Mirjam, de Fallois, Jonathan, Bläker, Hendrik, Bergmann, Carsten, Gödiker, Juliana, Schindler, Philipp, Schlevogt, Bernhard, Müller, Roman-U., Berg, Thomas, Patterson, Ilse, Griffiths, William J., Sayer, John A., Popp, Bernt, Torres, Vicente E., Hogan, Marie C., Somlo, Stefan, Watnick, Terry J., Nevens, Frederik, Besse, Whitney, Cornec-Le Gall, Emilie, Harris, Peter C., Drenth, Joost P.H., and Halbritter, Jan

Published
2024
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47. Sentinel node mapping in high-intermediate and high-risk endometrial cancer: Analysis of 5-year oncologic outcomes

Author

Cuccu, Ilaria, Raspagliesi, Francesco, Malzoni, Mario, Vizza, Enrico, Papadia, Andrea, Di Donato, Violante, Giannini, Andrea, De Iaco, Pierandrea, Perrone, Anna Myriam, Plotti, Francesco, Angioli, Roberto, Casarin, Jvan, Ghezzi, Fabio, Cianci, Stefano, Vizzielli, Giuseppe, Restaino, Stefano, Petrillo, Marco, Sorbi, Flavia, Multinu, Francesco, Schivardi, Gabriella, De Vitis, Luigi Antonio, Falcone, Francesca, Lalli, Luca, Berretta, Roberto, Mueller, Michael D., Tozzi, Roberto, Chiantera, Vito, Benedetti Panici, Pierluigi, Fanfani, Francesco, Scambia, Giovanni, and Bogani, Giorgio

Published
2024
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