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White waxy corn enjoys global popularity because of its appealing taste and distinctive texture. Although it serves as a dietary cornerstone in numerous regions, it is characterized by relatively modest nutritional content. The objective of this research is to investigate various soaking solutions (including citrate buffer pH 3.0, citrate buffer pH 3.0 with 0,5% vitamin B6, citrate buffer pH 3.0 with 0,5% vitamin B6 and 0,5% glutamic acid) and different germination periods (ranging from 0 to 96 hours) on the level of antioxidant activity, ɣ-aminobutyric acid (GABA), polyphenols, and protein in white waxy corn. The highest ABTS inhibition (66.8%) was achieved through the soaking process involving citrate buffer pH 3.0 combined with L-glutamic acid and vitamin B6 solution during 96-hour germination. In contrast, the highest GABA concentration (213.9 ppm) was attained using citrate buffer pH 3.0 for 96-hour germination. The highest protein content (3110.9 ppm) was observed after 72 hours of germination using a soaking solution of citrate buffer pH three combined with L-glutamic acid and vitamin B6. However, the highest polyphenol (5603.3 ppm) was obtained using citrate buffer pH three for 72 hours. Soaking and germination can improve the chemical composition and antioxidant activity of white waxy corn.

The issue that arises in Kadipaten subdistrict relates to behavioral aspects of operating a financial accounting system. This research aims to determine how behavioral factors influence the use of the Regional Accounting Financial System in Kadipaten subdistrict. In this study, the population is the Kadipaten subdistrict unit of the work device area (SKPD). This study is quantitative research. The type of data used in this research is primary data. Questionnaires were used for the data collection method, purposive sampling was used as the sampling technique, and multiple linear regression was used for data analysis with the aid of the SPSS program. This study's sample consisted of 35 respondents who worked in Kadipaten subdistrict. According to the results of the multiple linear regression test, the regional financial accounting system is partially affected in a significant and positive way by three factors: attitude, motivation, and perception. [ABSTRACT FROM AUTHOR]

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Butyrolactone I (1), a major compound of Aspergillus terreus know has a wide range of biological activities. In this report, butyrolactone I (1) has been isolated along with aspernolide A (2), butyrolactone II (3), butyrolactone III (4) from liquid fermentation of A. terreus. Furthermore, a series of butyrolactone I (1) derivatives 1.1-1.3 have been synthesized, and all compounds obtained were evaluated for their in vitro a-glucosidase inhibitory activity. The interaction of those compounds to the active site of the a-glucosidase enzyme from Saccharomyces cerevisiae was studied by the docking method. Among all the compounds, compound 1 exhibited potential activities against a-glucosidase with IC50 of 53.92 µM, when compared with the standard quercetin having IC50 value 31.29 µM. Docking studies of 1 showed hydrogen bonding interactions with Ser-311, Glu-411, Glu-277, Gln-279, arene-anion, and arene-cation interactions. The promising potential as an a-glucosidase inhibitor compound 1, was then further tested for in vivo toxicities using the DDY mice. Observations were carried out for 14 days, with no mortality was recorded in both of the male group and the female group. The compound 1 is practically non-toxic for female DDY mice (LD50>2,000 mg/kg). Based on these results suggest that the compound 1, could be a promising lead compound in the search for development a new a-glucosidase agen for future drug development against diabetes mellitus. [ABSTRACT FROM AUTHOR]

The antibiotic resistance of phatogenic bacteria has become a serious health concern and encouragement to search for novel and efficient antimicrobial metabolites. On the other hand, endophytic fungi have great potential as a natural source for antimicrobial agents. The objective of this study was to isolate antibacterial compound from endophytic fungi A.elegans SweF9. The fungus was stationarily cultured at 30°C for 12 days in potato malt peptone (PMP) medium, then the filtrate was extracted with ethyl acetate. The antibacterial activities of the extract were evaluated by agar diffusion method against Gram-poitive (Bacillus subtilis and Staphylococcus aureus) and Gramnegative (Escherichia coli) bacterial strains. The broth extract at a concentration of 1% was able to inhibit the growth of E. coli, S. aureus and B. subtilis with an index of antibacterial activity 84.6%, 91.6%, and 90% compared to streptomycin sulfate at the same concentration. The active compound (1) was purified to yield amorphous white and identified using FTIR, NMR, and EI-MS analyses, revealed identified as (+) - epi-Epoformin. The compound showed an antibacterial activity index of against E. coli, S. aureus and B. subtilis bacterial were 48%, 45%, and 47%, respectively, at concentration 1%. [ABSTRACT FROM AUTHOR]