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Objectives: We evaluated the contribution of lung lesion quantification on chest CT using a clinical Artificial Intelligence (AI) software in predicting death and intensive care units (ICU) admission for COVID-19 patients. Methods: For 349 patients with positive COVID-19-PCR test that underwent a chest CT scan at admittance or during hospitalization, we applied the AI for lung and lung lesion segmentation to obtain lesion volume (LV), and LV/Total Lung Volume (TLV) ratio. ROC analysis was used to extract the best CT criterion in predicting death and ICU admission. Two prognostic models using multivariate logistic regressions were constructed to predict each outcome and were compared using AUC values. The first model (“Clinical”) was based on patients’ characteristics and clinical symptoms only. The second model (“Clinical+LV/TLV”) included also the best CT criterion. Results: LV/TLV ratio demonstrated best performance for both outcomes; AUC of 67.8% (95% CI: 59.5 - 76.1) and 81.1% (95% CI: 75.7 - 86.5) respectively. Regarding death prediction, AUC values were 76.2% (95% CI: 69.9 - 82.6) and 79.9% (95%IC: 74.4 - 85.5) for the “Clinical” and the “Clinical+LV/TLV” models respectively, showing significant performance increase (+ 3.7%; p-value

Abstract  Fuzzy set theory constitutes a powerful representation framework that can lead to more robustness in problems such as image segmentation and recognition. This robustness results to some extent from the partial recovery of the continuity that is lost during digitization. In this paper we deal with connectivity measures on fuzzy sets. We show that usual fuzzy connectivity definitions have some drawbacks, and we propose a new definition that exhibits better properties, in particular in terms of continuity. This definition leads to a nested family of hyperconnections associated with a tolerance parameter. We show that corresponding connected components can be efficiently extracted using simple operations on a max-tree representation. Then we define attribute openings based on crisp or fuzzy criteria. We illustrate a potential use of these filters in a brain segmentation and recognition process. [ABSTRACT FROM AUTHOR]