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1. Effects of tricuspid transcatheter edge-to-edge repair on tricuspid annulus diameter - Data from the TriValve registry

Author

Russo, Giulio, Hahn, Rebecca T., Alessandrini, Hannes, Andreas, Martin, Badano, Luigi P., Braun, Daniel, Connelly, Kim A., Denti, Paolo, Estevez-Loureiro, Rodrigo, Fam, Neil, Gavazzoni, Mara, Hausleiter, Joerg, Himbert, Dominique, Kalbacher, Daniel, Latib, Azeem, Lubos, Edith, Ludwig, Sebastian, Lurz, Philipp, Monivas, Vanessa, Nickenig, Georg, Pedicino, Daniela, Pedrazzini, Giovanni, Pozzoli, Alberto, Praz, Fabien, Rodes-Cabau, Joseph, Rommel, Karl-Philipp, Schofer, Joachim, Sievert, Horst, Tang, Gilbert, Thiele, Holger, Unterhuber, Matthias, von Bardeleben, Ralph Stephan, Webb, John, Windecker, Stephan, Leon, Martin, Maisano, Francesco, and Taramasso, Maurizio

Published
2024
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2. Prediction of Mortality and Heart Failure Hospitalization After Transcatheter Tricuspid Valve Interventions: Validation of TRISCORE

Author

Adamo, Marianna, Russo, Giulio, Pagnesi, Matteo, Pancaldi, Edoardo, Alessandrini, Hannes, Andreas, Martin, Badano, Luigi P., Braun, Daniel, Connelly, Kim A., Denti, Paolo, Estevez-Loureiro, Rodrigo, Fam, Neil, Gavazzoni, Mara, Hahn, Rebecca T., Harr, Claudia, Hausleiter, Joerg, Himbert, Dominique, Kalbacher, Daniel, Ho, Edwin, Latib, Azeem, Lubos, Edith, Ludwig, Sebastian, Lupi, Laura, Lurz, Philipp, Monivas, Vanessa, Nickenig, Georg, Pedicino, Daniela, Pedrazzini, Giovanni, Pozzoli, Alberto, Marafon, Denise Pires, Pastorino, Roberta, Praz, Fabien, Rodes-Cabau, Joseph, Besler, Christian, Schöber, Anne Rebecca, Schofer, Joachim, Scotti, Andrea, Piayda, Kerstin, Sievert, Horst, Tang, Gilbert H.L., Sticchi, Alessandro, Messika-Zeitoun, David, Thiele, Holger, Schlotter, Florian, von Bardeleben, Ralph Stephan, Webb, John, Dreyfus, Julien, Windecker, Stephan, Leon, Martin, Maisano, Francesco, Metra, Marco, and Taramasso, Maurizio

Published
2024
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3. Prognostic Value of Tricuspid Valve Gradient After Transcatheter Edge-to-Edge Repair: Insights From the TriValve Registry

Author

Coisne, Augustin, Scotti, Andrea, Taramasso, Maurizio, Granada, Juan F., Ludwig, Sebastian, Rodés-Cabau, Josep, Lurz, Philipp, Hausleiter, Jörg, Fam, Neil, Kodali, Susheel K., Pozzoli, Alberto, Alessandrini, Hannes, Biasco, Luigi, Brochet, Eric, Denti, Paolo, Estevez-Loureiro, Rodrigo, Frerker, Christian, Ho, Edwin C., Monivas, Vanessa, Nickenig, Georg, Praz, Fabien, Puri, Rishi, Sievert, Horst, Tang, Gilbert H.L., Andreas, Martin, Von Bardeleben, Ralph Stephan, Rommel, Karl-Philipp, Muntané-Carol, Guillem, Gavazzoni, Mara, Braun, Daniel, Lubos, Edith, Kalbacher, Daniel, Connelly, Kim A., Juliard, Jean-Michel, Harr, Claudia, Pedrazzini, Giovanni, Philippon, François, Schofer, Joachim, Thiele, Holger, Unterhuber, Matthias, Himbert, Dominique, Alcázar, Marina Ureña, Wild, Mirjam G., Jorde, Ulrich, Windecker, Stephan, Maisano, Francesco, Leon, Martin B., Hahn, Rebecca T., and Latib, Azeem

Published
2023
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5. Transcatheter Tricuspid Valve Intervention in Patients With Previous Left Valve Surgery

Author

Muntané-Carol, Guillem, Taramasso, Maurizio, Miura, Mizuki, Gavazzoni, Mara, Pozzoli, Alberto, Alessandrini, Hannes, Latib, Azeem, Attinger-Toller, Adrian, Biasco, Luigi, Braun, Daniel, Brochet, Eric, Connelly, Kim A., Sievert, Horst, Denti, Paolo, Lubos, Edith, Ludwig, Sebastian, Kalbacher, Daniel, Estevez-Loureiro, Rodrigo, Fam, Neil, Frerker, Christian, Ho, Edwin, Juliard, Jean-Michel, Kaple, Ryan, Kodali, Susheel, Kreidel, Felix, Harr, Claudia, Lauten, Alexander, Lurz, Julia, Kresoja, Karl-Patrik, Monivas, Vanessa, Mehr, Michael, Nazif, Tamim, Nickening, Georg, Pedrazzini, Giovanni, Philippon, François, Praz, Fabien, Puri, Rishi, Schäfer, Ulrich, Schofer, Joachim, Tang, Gilbert H.L., Khattab, Ahmed A., Andreas, Martin, Russo, Marco, Thiele, Holger, Unterhuber, Matthias, Himbert, Dominique, Urena, Marina, von Bardeleben, Ralph Stephan, Webb, John G., Weber, Marcel, Winkel, Mirjam, Zuber, Michel, Hausleiter, Jörg, Lurz, Philipp, Maisano, Francesco, Leon, Martin B., Hahn, Rebecca T., and Rodés-Cabau, Josep

Published
2021
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6. Early Multinational Experience of Transcatheter Tricuspid Valve Replacement for Treating Severe Tricuspid Regurgitation

Author

Hahn, Rebecca T., Kodali, Susheel, Fam, Neil, Bapat, Vinayak, Bartus, Krzysztof, Rodés-Cabau, Josep, Dagenais, Francois, Estevez-Loureiro, Rodrigo, Forteza, Alberto, Kapadia, Samir, Latib, Azeem, Maisano, Francesco, McCarthy, Patrick, Navia, Jose, Ong, Geraldine, Peterson, Mark, Petrossian, George, Pozzoli, Alberto, Reinartz, Markus, Ricciardi, Mark J., Robinson, Newell, Sievert, Horst, Taramasso, Maurizio, Agarwal, Vratika, Bédard, Elisabeth, Tarantini, Giuseppe, and Colli, Andrea

Published
2020
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8. Impact of Massive or Torrential Tricuspid Regurgitation in Patients Undergoing Transcatheter Tricuspid Valve Intervention

Author

Miura, Mizuki, Alessandrini, Hannes, Alkhodair, Abdullah, Attinger-Toller, Adrian, Biasco, Luigi, Lurz, Philipp, Braun, Daniel, Brochet, Eric, Connelly, Kim A., de Bruijn, Sabine, Denti, Paolo, Deuschl, Florian, Estevez-Loureiro, Rodrigo, Fam, Neil, Frerker, Christian, Gavazzoni, Mara, Hausleiter, Jörg, Himbert, Dominique, Ho, Edwin, Juliard, Jean-Michel, Kaple, Ryan, Besler, Christian, Kodali, Susheel, Kreidel, Felix, Kuck, Karl-Heinz, Latib, Azeem, Lauten, Alexander, Monivas, Vanessa, Mehr, Michael, Muntané-Carol, Guillem, Nazif, Tamin, Nickenig, Georg, Pedrazzini, Giovanni, Philippon, François, Pozzoli, Alberto, Praz, Fabien, Puri, Rishi, Rodés-Cabau, Josep, Schäfer, Ulrich, Schofer, Joachim, Sievert, Horst, Tang, Gilbert H.L., Thiele, Holger, Rommel, Karl-Philipp, Vahanian, Alec, Von Bardeleben, Ralph Stephan, Webb, John G., Weber, Marcel, Windecker, Stephan, Winkel, Mirjam, Zuber, Michel, Leon, Martin B., Maisano, Francesco, Hahn, Rebecca T., and Taramasso, Maurizio

Published
2020
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9. Value of Echocardiographic Right Ventricular and Pulmonary Pressure Assessment in Predicting Transcatheter Tricuspid Repair Outcome

Author

Karam, Nicole, Mehr, Michael, Taramasso, Maurizio, Besler, Christian, Ruf, Tobias, Connelly, Kim A., Weber, Marcel, Yzeiraj, Ermela, Schiavi, Davide, Mangieri, Antonio, Vaskelyte, Laura, Alessandrini, Hannes, Deuschl, Florian, Brugger, Nicolas, Ahmad, Hasan, Ho, Edwin, Biasco, Luigi, Orban, Mathias, Deseive, Simon, Braun, Daniel, Gavazzoni, Mara, Rommel, Karl-Philipp, Pozzoli, Alberto, Frerker, Christian, Näbauer, Michael, Massberg, Steffen, Pedrazzini, Giovanni, Tang, Gilbert H.L., Windecker, Stephan, Schäfer, Ulrich, Kuck, Karl-Heinz, Sievert, Horst, Denti, Paolo, Latib, Azeem, Schofer, Joachim, Nickenig, Georg, Fam, Neil, von Bardeleben, Stephan, Lurz, Philipp, Maisano, Francesco, and Hausleiter, Jörg

Published
2020
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10. Transcatheter Edge-to-Edge Tricuspid Repair for Severe Tricuspid Regurgitation Reduces Hospitalizations for Heart Failure

Author

Orban, Mathias, Rommel, Karl-Philipp, Ho, Edwin C., Unterhuber, Matthias, Pozzoli, Alberto, Connelly, Kim A., Deseive, Simon, Besler, Christian, Ong, Geraldine, Braun, Daniel, Edwards, Jeremy, Miura, Mizuki, Gülmez, Gökhan, Stolz, Lukas, Gavazzoni, Mara, Zuber, Michel, Orban, Martin, Nabauer, Michael, Maisano, Francesco, Thiele, Holger, Massberg, Steffen, Taramasso, Maurizio, Fam, Neil P., Lurz, Philipp, and Hausleiter, Jörg

Published
2020
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11. Outcomes of TTVI in Patients With Pacemaker or Defibrillator Leads: Data From the TriValve Registry

Author

Taramasso, Maurizio, Gavazzoni, Mara, Pozzoli, Alberto, Alessandrini, Hannes, Latib, Azeem, Attinger-Toller, Adrian, Biasco, Luigi, Braun, Daniel, Brochet, Eric, Connelly, Kim A., de Bruijn, Sabine, Denti, Paolo, Deuschl, Florian, Estevez-Louriero, Rodrigo, Fam, Neil, Frerker, Christian, Ho, Edwin, Juliard, Jean-Michel, Kaple, Ryan, Kodali, Susheel, Kreidel, Felix, Kuck, Karl-Heinz, Lauten, Alexander, Lurz, Julia, Monivas, Vanessa, Mehr, Michael, Nazif, Tamin, Nickening, Georg, Pedrazzini, Giovanni, Praz, Fabien, Puri, Rishi, Rodés-Cabau, Josep, Schäfer, Ulrich, Schofer, Joachim, Sievert, Horst, Tang, Gilbert H.L., Khattab, Ahmed A., Thiele, Holger, Unterhuber, Matthias, Vahanian, Alec, Von Bardeleben, Ralph Stephan, Webb, John G., Weber, Marcel, Windecker, Stephan, Winkel, Mirjam, Zuber, Michel, Hausleiter, Jörg, Lurz, Philipp, Maisano, Francesco, Leon, Martin B., and Hahn, Rebecca T.

Published
2020
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12. Combined Tricuspid and Mitral Versus Isolated Mitral Valve Repair for Severe MR and TR: An Analysis From the TriValve and TRAMI Registries

Author

Connelly, Kim, Denti, Paolo, Schiavi, Davide, Weber, Marcel, Nickenig, Georg, Frerker, Christian, Sievert, Horst, Vaskelyte, Laura, Schäfer, Ulrich, Kalbacher, Daniel, Deuschl, Florian, Kuck, Karl-Heinz, Allessandrini, Hannes, Besler, Christian, Rommel, Karl-Philipp, Ruf, Tobias, Orban, Mathias, Stocker, Thomas, Deseive, Simon, Braun, Daniel, Näbauer, Michael, Massberg, Steffen, Bekeredjian, Raffi, Meyer-Zuern, Christine S., Pedrazzini, Giovanni, Biasco, Luigi, Pozzoli, Alberto, Mehr, Michael, Karam, Nicole, Taramasso, Maurizio, Ouarrak, Taoufik, Schneider, Steffen, Lurz, Philipp, von Bardeleben, Ralph Stephan, Fam, Neil, Lubos, Edith, Boekstegers, Peter, Schillinger, Wolfgang, Plicht, Björn, Eggebrecht, Holger, Baldus, Stephan, Senges, Jochen, Maisano, Francesco, and Hausleiter, Jörg

Published
2020
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13. Similar outcome of tricuspid valve repair and replacement for isolated tricuspid infective endocarditis

Author

Di Mauro, Michele, Bonalumi, Giorgia, Giambuzzi, Ilaria, Dato, Guglielmo Mario Actis, Centofanti, Paolo, Corte, Alessandro Della, Ratta, Ester Della, Cugola, Diego, Merlo, Maurizio, Santini, Francesco, Salsano, Antonio, Rinaldi, Mauro, Mancuso, Samuel, Cappabianca, Giangiuseppe, Beghi, Cesare, De Vincentiis, Carlo, Biondi, Andrea, Livi, Ugolino, Sponga, Sandro, Pacini, Davide, Murana, Giacomo, Scrofani, Roberto, Antona, Carlo, Cagnoni, Giovanni, Nicolini, Francesco, Benassi, Filippo, De Bonis, Michele, Pozzoli, Alberto, Pano, Marco, Nicolardi, Salvatore, Falcetta, Giosuè, Colli, Andrea, Musumeci, Francesco, Gherli, Riccardo, Vizzardi, Enrico, Salvador, Loris, Picichè, Marco, Paparella, Domenico, Margari, Vito, Troise, Giovanni, Villa, Emmanuel, Dossena, Yudit, Lucarelli, Carla, Onorati, Francesco, Faggian, Giuseppe, Mariscalco, Giovanni, Maselli, Daniele, Barili, Fabio, Parolari, Alessandro, and Lorusso, Roberto

Published
2022
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14. Surgical treatment of isolated tricuspid valve infective endocarditis: 25-year results from a multicenter registry

Author

Di Mauro, Michele, Foschi, Massimiliano, Dato, Guglielmo Mario Actis, Centofanti, Paolo, Barili, Fabio, Corte, Alessandro Della, Ratta, Ester Della, Cugola, Diego, Galletti, Lorenzo, Santini, Francesco, Salsano, Antonio, Rinaldi, Mauro, Mancuso, Samuel, Cappabianca, Giangiuseppe, Beghi, Cesare, De Vincentiis, Carlo, Biondi, Andrea, Livi, Ugolino, Sponga, Sandro, Pacini, Davide, Murana, Giacomo, Scrofani, Roberto, Antona, Carlo, Cagnoni, Giovanni, Nicolini, Francesco, Benassi, Filippo, De Bonis, Michele, Pozzoli, Alberto, Casali, Giovanni, Scrascia, Giuseppe, Falcetta, Giosuè, Bortolotti, Uberto, Musumeci, Francesco, Gherli, Riccardo, Vizzardi, Enrico, Salvador, Loris, Picichè, Marco, Paparella, Domenico, Margari, Vito, Troise, Giovanni, Villa, Emmanuel, Dossena, Yudit, Lucarelli, Carla, Onorati, Francesco, Faggian, Giuseppe, Mariscalco, Giovanni, Maselli, Daniele, Parolari, Alessandro, and Lorusso, Roberto

Published
2019
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15. 1-Year Outcomes After Edge-to-Edge Valve Repair for Symptomatic Tricuspid Regurgitation: Results From the TriValve Registry

Author

Mehr, Michael, Taramasso, Maurizio, Besler, Christian, Ruf, Tobias, Connelly, Kim A., Weber, Marcel, Yzeiraj, Ermela, Schiavi, Davide, Mangieri, Antonio, Vaskelyte, Laura, Alessandrini, Hannes, Deuschl, Florian, Brugger, Nicolas, Ahmad, Hasan, Biasco, Luigi, Orban, Mathias, Deseive, Simon, Braun, Daniel, Rommel, Karl-Philipp, Pozzoli, Alberto, Frerker, Christian, Näbauer, Michael, Massberg, Steffen, Pedrazzini, Giovanni, Tang, Gilbert H.L., Windecker, Stephan, Schäfer, Ulrich, Kuck, Karl-Heinz, Sievert, Horst, Denti, Paolo, Latib, Azeem, Schofer, Joachim, Nickenig, Georg, Fam, Neil, von Bardeleben, Stephan, Lurz, Philipp, Maisano, Francesco, and Hausleiter, Jörg

Published
2019
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18. Outcomes After Current Transcatheter Tricuspid Valve Intervention: Mid-Term Results From the International TriValve Registry

Author

Taramasso, Maurizio, Alessandrini, Hannes, Latib, Azeem, Asami, Masahiko, Attinger-Toller, Adrian, Biasco, Luigi, Braun, Daniel, Brochet, Eric, Connelly, Kim A., Denti, Paolo, Deuschl, Florian, Englmeier, Andrea, Fam, Neil, Frerker, Christian, Hausleiter, Jörg, Himbert, Dominique, Ho, Edwin C., Juliard, Jean-Michel, Kaple, Ryan, Kreidel, Felix, Kuck, Karl-Heinz, Ancona, Marco, Lauten, Alexander, Lurz, Philipp, Mehr, Michael, Nazif, Tamin, Nickening, Georg, Pedrazzini, Giovanni, Pozzoli, Alberto, Praz, Fabien, Puri, Rishi, Rodés-Cabau, Josep, Schäfer, Ulrich, Schofer, Joachim, Sievert, Horst, Sievert, Kolja, Tang, Gilbert H.L., Tanner, Felix C., Vahanian, Alec, Webb, John G., Windecker, Stephan, Yzeiray, Ermela, Zuber, Michel, Maisano, Francesco, Leon, Martin B., and Hahn, Rebecca T.

Published
2019
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20. Minimally Invasive Isolated and Hybrid Surgical Revascularization for Multivessel Coronary Disease: A Single-Center Long-Term Follow-Up.

Author

Torre, Tiziano, Pozzoli, Alberto, Valgimigli, Marco, Leo, Laura Anna, Toto, Francesca, Muretti, Mirko, Birova, Sara, Ferrari, Enrico, Pedrazzini, Giovanni, and Demertzis, Stefanos

Subjects
*REVASCULARIZATION (Surgery), *DRUG-eluting stents, *CORONARY disease, *PERCUTANEOUS coronary intervention, *HOSPITAL mortality, *CORONARY artery bypass
Abstract

Introduction: Some evidence suggests that surgical minimally invasive (MIDCAB) and hybrid coronary revascularization (HCR) are safe and potentially effective at short-term follow-up. Data on long-term outcomes are more limited and inconclusive. Methods: Between February 2013 and December 2023, a total of 1997 patients underwent surgical coronary artery revascularization at our institution, of whom, 92 (4.7%) received left anterior mini-thoracotomy access (MIDCAB), either isolated (N = 78) or in combination with percutaneous coronary intervention (N = 14, HCR group). Results: After a median follow-up of 75 months (range 3.1: 149 months), cardiac mortality was 0% while overall mortality was 3%, with one in-hospital mortality and two additional late deaths. Conversion to sternotomy happened in two patients (2.1%), and surgical re-explorations occurred in five patients (4.6%), of whom three for bleeding and two for graft failure. All patients received left internal mammary (LIMA) to left anterior descending artery (LAD) grafting (100%). In the HCR group, 10 patients (72%) showed percutaneous revascularization (PCI) after MIDCAB, showing PCI on a mean of 1.6 ± 0.6 vessels and implanting 2.1 ± 0.9 drug-eluting stents. Conclusions: MIDCAB, in isolation or in association with hybrid coronary revascularization, is associated with encouraging short- and long-term results in selected patients discussed within a dedicated heart-team. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Continuous Glucose Monitoring System After Coronary Artery Bypass Graft Surgery: A Feasibility Study.

Author

Torre, Tiziano, Schlotterbeck, Hervé, Ferraro, Francesco, Klersy, Catherine, Surace, Giuseppina, Toto, Francesca, Pozzoli, Alberto, Ferrari, Enrico, and Demertzis, Stefanos

Abstract

Background: Blood glucose level variability has been associated with increased risk of complication in the postoperative setting of cardiovascular surgery. Although interesting for optimization of blood glucose management in this context, continuous blood glucose (CBG) devices can have a limited reliability in this context, in particular because of the use of paracetamol. The aim of this study was to evaluate the reliability of Dexcom G6®, a recently developed continuous glucose monitoring device. Methods: We performed a prospective, observational, non-randomized, single-centre study comparing Dexcom G6® CBG level monitoring with the standard methods routinely used in this context. The standard blood glucose values were paired to the time corresponding values measured with Dexcom G6®. Agreement between the two methods and potential correlation in case of paracetamol use were calculated. Results: From May 2020 to August 2021, 36 out of 206 patients operated for isolated coronary artery bypass grafting were enrolled; 673 paired blood glucose level were analyzed. Global agreement (ρc) was 0.85 (95% C.I.: 0.84–0.86), intensive care unit agreement was 0.78 (95%C.I.: 0.74–0.82) and ward agreement was 0.91 (95%C.I.: 0.89–0.93). In the diabetic population, it was 0.87 (95%C.I.: 0.85–0.90). When paracetamol was used, the difference was 0.02 mmol/l (95%C.I.: 0.29–0.33). Conclusions: Dexcom G6® provides good blood glucose level accuracy in the postoperative context of cardiac surgery compared to the standard methods of measurements. The results are particularly reliable in the ward where the need for repeated capillary glucose measurements implies patient discomfort and time-consuming manipulations for the nursing staff. [ABSTRACT FROM AUTHOR]

Published
2024
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23. The International Multicenter TriValve Registry: Which Patients Are Undergoing Transcatheter Tricuspid Repair?

Author

Taramasso, Maurizio, Hahn, Rebecca T., Alessandrini, Hannes, Latib, Azeem, Attinger-Toller, Adrian, Braun, Daniel, Brochet, Eric, Connelly, Kim A., Denti, Paolo, Deuschl, Florian, Englmaier, Andrea, Fam, Neil, Frerker, Christian, Hausleiter, Joerg, Juliard, Jean-Michel, Kaple, Ryan, Kreidel, Felix, Kuck, Karl Heinz, Kuwata, Shingo, Ancona, Marco, Malasa, Margarita, Nazif, Tamim, Nickenig, Georg, Nietlispach, Fabian, Pozzoli, Alberto, Schäfer, Ulrich, Schofer, Joachim, Schueler, Robert, Tang, Gilbert, Vahanian, Alec, Webb, John G., Yzeiraj, Ermela, Maisano, Francesco, and Leon, Martin B.

Published
2017
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24. A predictive model for early mortality after surgical treatment of heart valve or prosthesis infective endocarditis. The EndoSCORE

Author

Di Mauro, Michele, Dato, Guglielmo Mario Actis, Barili, Fabio, Gelsomino, Sandro, Santè, Pasquale, Corte, Alessandro Della, Carrozza, Antonio, Ratta, Ester Della, Cugola, Diego, Galletti, Lorenzo, Devotini, Roger, Casabona, Riccardo, Santini, Francesco, Salsano, Antonio, Scrofani, Roberto, Antona, Carlo, Botta, Luca, Russo, Claudio, Mancuso, Samuel, Rinaldi, Mauro, De Vincentiis, Carlo, Biondi, Andrea, Beghi, Cesare, Cappabianca, Giangiuseppe, Tarzia, Vincenzo, Gerosa, Gino, De Bonis, Michele, Pozzoli, Alberto, Nicolini, Francesco, Benassi, Filippo, Rosato, Francesco, Grasso, Elena, Livi, Ugolino, Sponga, Sandro, Pacini, Davide, Di Bartolomeo, Roberto, De Martino, Andrea, Bortolotti, Uberto, Onorati, Francesco, Faggian, Giuseppe, Lorusso, Roberto, Vizzardi, Enrico, Di Giammarco, Gabriele, Marinelli, Daniele, Villa, Emmanuel, Troise, Giovanni, Picichè, Marco, Musumeci, Francesco, Paparella, Domenico, Margari, Vito, Tritto, Francesco, Damiani, Girolamo, Scrascia, Giuseppe, Zaccaria, Salvatore, Renzulli, Attilio, Serraino, Giuseppe, Mariscalco, Giovanni, Maselli, Daniele, Foschi, Massimiliano, Parolari, Alessandro, and Nappi, Giannantonio

Published
2017
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26. del Nido versus hematic cardioplegia in minimally invasive aortic valve surgery.

Author

Pozzoli, Alberto, Gabriella Surace, Giuseppina, Torre, Tiziano, Bagnato, Pietro, Gallo, Michele, Toto, Francesca, Ferrari, Enrico, and Demertzis, Stefanos

Abstract

Background: The quality of a myocardial protection of a single-dose del Nido cardioplegia versus multiple dose blood-based cardioplegia on myocardial injury, outcomes and operative times in patients undergoing minimally invasive aortic valve replacement is basically unreported. Methods and Results: Preoperative and post-operative data, as well as technical details from isolated minimally invasive aortic valve replacements, performed using single-dose or multiple-dose cardioplegia were prospectively collected and retrospectively analysed. A total of 110 patients undergoing minimally invasive valve replacements at our institution composed two groups: 55 patients in the blood cardioplegia group (BloCa) and 55 in the del Nido group (DeNiCa). The two-matched groups were comparable in terms of preoperative variables. In the DeNiCa group, there was a statistically significant less need for cardiac defibrillation after aortic cross-clamp release (p < 0.001). Moreover, the BloCa group received intraoperatively more blood transfusions (p = 0.001) and more insulin administration for higher glucose levels (p < 0.001). The BloCa group showed higher intraoperative lactate levels (p = 0.01). Need for post-operative inotropic and vasoactive support, Creatine Kinase-MB levels after 6 and 12 h, onset of post-operative atrial fibrillation and length of stay were similar. No deaths occurred in neither groups. Conclusion: Single-dose del Nido cardioplegia in the setting of minimally invasive aortic surgery seems to offer adequate myocardial protection, comparable to multiple dose hematic cardioplegia. It has been documented a lower peri-operative need of defibrillation after cross-clamp release, lactate- and glucose peak values, as well as less blood transfusions compared to blood cardioplegic strategy. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Prosthetic valve endocarditis: predictors of early outcome of surgical therapy. A multicentric study

Author

Luciani, Nicola, Mossuto, Eugenio, Ricci, Davide, Luciani, Marco, Russo, Marco, Salsano, Antonio, Pozzoli, Alberto, Pierri, Michele D., D’Onofrio, Augusto, Chiariello, Giovanni A., Glieca, Franco, Canziani, Alberto, Rinaldi, Mauro, Nardi, Paolo, Milazzo, Valentina, Trecarichi, Enrico M., Santini, Francesco, De Bonis, Michele, Torracca, Lucia, Bizzotto, Eleonora, and Tumbarello, Mario

Published
2017
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38. Sex-related characteristics and short-term outcomes of patients undergoing transcatheter tricuspid valve intervention for tricuspid regurgitation.

Author

Scotti, Andrea, Coisne, Augustin, Taramasso, Maurizio, Granada, Juan F, Ludwig, Sebastian, Rodés-Cabau, Josep, Lurz, Philipp, Hausleiter, Jörg, Fam, Neil, Kodali, Susheel K, Rosiene, Joel, Feinberg, Ari, Pozzoli, Alberto, Alessandrini, Hannes, Biasco, Luigi, Brochet, Eric, Denti, Paolo, Estévez-Loureiro, Rodrigo, Frerker, Christian, and Ho, Edwin C

Subjects
TRICUSPID valve surgery, TRICUSPID valve, TREATMENT effectiveness
Abstract

Aims The impact of sexuality in patients with significant tricuspid regurgitation (TR) undergoing transcatheter tricuspid valve intervention (TTVI) is unknown. The aim of this study was to investigate sex-specific outcomes in patients with significant TR treated with TTVI vs. medical therapy alone. Methods and results The Transcatheter Tricuspid Valve Therapies (TriValve) registry collected data on patients with significant TR from 24 centres who underwent TTVI from 2016 to 2021. A control cohort was formed by medically managed patients with ≥severe isolated TR diagnosed in 2015–18. The primary endpoint was freedom from all-cause mortality. Secondary endpoints were heart failure (HF) hospitalization, New York Heart Association (NYHA) functional status, and TR severity. One-year outcomes were assessed for the TriValve cohort and compared with the control cohort with the inverse probability of treatment weighting (IPTW). A total of 556 and 2072 patients were included from the TriValve and control groups, respectively. After TTVI, there was no difference between women and men in 1-year freedom from all-cause mortality 80.9% vs. 77.9%, P = 0.56, nor in HF hospitalization (P = 0.36), NYHA Functional Classes III and IV (P = 0.17), and TR severity >2+ at last follow-up (P = 0.42). Multivariable Cox-regression weighted by IPTW showed improved 1-year survival after TTVI compared with medical therapy alone in both women (adjusted hazard ratio 0.45, 95% confidence interval 0.23–0.83, P = 0.01) and men (adjusted hazard ratio 0.42, 95% confidence interval 0.18–0.89, P = 0.03). Conclusion After TTVI in high-risk patients, there were no sex-related differences in terms of survival, HF hospitalization, functional status, and TR reduction up to 1 year. The IPTW analysis shows a survival benefit of TTVI over medical therapy alone in both women and men. [ABSTRACT FROM AUTHOR]

Published
2023
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41. Twenty‐year experience with skeletonized bilateral internal thoracic arteries for surgical myocardial revascularization. A single center experience.

Author

Torre, Tiziano M., Toto, Francesca, Klersy, Catherine, Theologou, Thomas, Pozzoli, Alberto, Ferrari, Enrico, and Demertzis, Stefanos

Subjects
INTERNAL thoracic artery, REVASCULARIZATION (Surgery), CHRONIC kidney failure, MYOCARDIAL revascularization, THORACIC arteries, INJURY risk factors
Abstract

Background and Aim of the study: The mammary artery shows excellent long‐term patency and encourages the use of skeletonized bilateral internal thoracic arteries (BITA) for coronary surgery. We analyzed the long‐term outcome of patients operated for myocardial revascularization with BITA in a single center. Materials and Methods: Clinical data and surgical details of patients undergoing coronary surgery with BITA were prospectively collected and retrospectively analyzed. Selected variables were studied as risk factors for sternal wound complication and a subanalysis of clinical outcome for patients aged 70 years or greater was performed. A long‐term follow‐up of the study group is provided. Results: From January 2001 to November 2021, 750 patients underwent myocardial revascularization using BITA grafts (mean age: 61 ± 9.5 years; males: 91%) at our institute. Patients with triple‐vessel disease were 81%, 15.3% of all procedures were performed off‐pump and 3.6% were urgent cases. Hospital mortality was 0.5%. Sternal wound complication was observed in 67 patients (9.0%) with 7 deep sternal wound infections (0.9%). Female gender (odds ratios [OR]: 3.7, p < 0.01), BMI >30 (OR: 1.8, p = 0.04), smoking (OR: 1.8, p = 0.02), and chronic kidney failure (OR: 3.7, p = 0.05) were independent predictors for sternal complications. During a mean follow‐up time of 8.7 ± 5.3 years, 34 patients (4.5%) underwent a repeated myocardial revascularization, and there were 89 all‐cause deaths (11.9%) and the cumulative survival at 5, 10, 15, and 20 years was 97%, 89%, 76%, and 60% for the whole study group 92%, 74%, 47%, and 43% for the subgroup of elderly patients (mean age: 74 ± 3.5 years). Conclusions: Use of skeletonized bilateral thoracic arteries shows low‐rate of wound infection and good long‐term outcome with low risk of repeated revascularizations, regardless of patients' age. [ABSTRACT FROM AUTHOR]

Published
2022
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42. Conventional surgery and transcatheter closure via surgical transapical approach for paravalvular leak repair in high-risk patients: results from a single-centre experience

Author

Taramasso, Maurizio, Maisano, Francesco, Latib, Azeem, Denti, Paolo, Guidotti, Andrea, Sticchi, Alessandro, Panoulas, Vasileios, Giustino, Gennaro, Pozzoli, Alberto, Buzzatti, Nicola, Cota, Linda, De Bonis, Michele, Montorfano, Matteo, Castiglioni, Alessandro, Blasio, Andrea, La Canna, Giovanni, Colombo, Antonio, and Alfieri, Ottavio

Published
2014
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46. Apical closure device for full‐percutaneous transapical structural and valve procedures with large‐sized introducer sheaths: The final preclinical study.

Author

Ferrari, Enrico, Pozzoli, Alberto, Maisano, Francesco, and von Segesser, Ludwig K.

Abstract

Background: Closed‐chest transapical valve implantations (aortic, mitral, and tricuspid) and cardiac structural procedures requiring large‐sized introducer sheaths cannot be safely performed with the available technology. We tested a self‐expanding apical closure device in a closed‐chest animal model, using large‐sized introducer sheaths and human‐sized animals to establish the technique for future tests in humans. Methods: Six human‐sized pigs (mean weight: 89.7 ± 3.7 kg) received general anesthesia, intubation, and full heparinization (15,000 IU/animal; expected activated clotting time >200 s). Under fluoroscopy and multimodality imaging guidance with next‐generation fusion imaging prototypes, a 15‐cm long needle and a standard guidewire were percutaneously inserted under the xiphoidal aponeurosis and into the ventricular apex. After the exchange with a stiff guidewire, a 21‐Fr introducer sheath for transapical procedures (outer diameter: 25‐Fr) was placed in the left ventricle through the apex. The self‐expanding closure device was inserted and deployed under fluoroscopic guidance while the 21‐Fr sheath was gently removed. Hemodynamic conditions were monitored for 30 min and then the chest was opened to inspect the closure device and quantify the blood loss in the pericardium. Animals were killed and the hearts were removed and inspected. Results: All six apical closure devices were successfully deployed without adverse events. No death, hemodynamic collapse, or cardiac tamponade occurred during the 30‐min observational period (mean systolic and diastolic pressures: 88 ± 11 and 58 ± 13 mmHg, respectively; mean heart rate: 60 ± 11 beats per minutes). Pre‐ and postdeployment (after protamine administration) mean activated clotting time was 541 ± 263 and 217 ± 62 s, respectively. The plugs provided good sealing with a mean of 27.2 ± 13.86 ml of blood lost in the pericardium. Postmortem inspection showed good plug fixation without myocardial damage. Conclusion: This self‐expanding apical closure device successfully sealed the percutaneous access sites made with large‐sized introducer sheaths in human‐sized animals. This preclinical study suggests that transapical valve and structural procedures requiring large‐sized introducer sheaths can be performed percutaneously. [ABSTRACT FROM AUTHOR]

Published
2022
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50. Challenges and future perspectives of transcatheter tricuspid valve interventions: adopt old strategies or adapt to new opportunities?

Author

Russo, Giulio, Taramasso, Maurizio, Pedicino, Daniela, Gennari, Marco, Gavazzoni, Mara, Pozzoli, Alberto, Muraru, Denisa, Badano, Luigi P., Metra, Marco, and Maisano, Francesco

Subjects
TRICUSPID valve surgery, CARDIAC surgery, TRICUSPID valve diseases, PROSTHETIC heart valves
Abstract

Tricuspid regurgitation (TR) is a highly prevalent valvular heart disease and is associated with an increased risk of cardiovascular events and death at long-term follow-up. Functional TR accounts for over 90% of TR and is mainly due to annular or right ventricular dilatation. Most often, TR is observed in patients with left-sided valvular heart disease (with or without previous surgical correction) and pulmonary hypertension. Isolated TR is less frequent, though burdened by high surgical mortality. This, together with an incomplete understanding of the disease, has brought to a significant undertreatment in spite of the growing evidence of the impact of severe TR on mortality. Moreover, uncertainties about the appropriate timing for intervention and the predictors of procedural success have contributed to limit TR treatment. Transcatheter tricuspid valve replacement or repair interventions represent novel and less invasive alternatives to surgery and have shown early promising results. The purpose of this review is to provide a complete and updated overview of TR pathology with a special focus on current percutaneous treatment options, future challenges and directions. [ABSTRACT FROM AUTHOR]

Published
2022
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