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Your search keyword '"Quarantelli, Mario"' showing total 335 results
Start Over Author "Quarantelli, Mario" Publication Type Academic Journals
335 results on '"Quarantelli, Mario"'

7. Clinical indications and acquisition protocol for the use of dynamic contrast-enhanced MRI in head and neck cancer squamous cell carcinoma: recommendations from an expert panel

Author

Romeo, Valeria, Stanzione, Arnaldo, Ugga, Lorenzo, Cuocolo, Renato, Cocozza, Sirio, Quarantelli, Mario, Chawla, Sanjeev, Farina, Davide, Golay, Xavier, Parker, Geoff, Shukla-Dave, Amita, Thoeny, Harriet, Vidiri, Antonello, Brunetti, Arturo, Surlan-Popovic, Katarina, and Bisdas, Sotirios

Published
2022
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8. ProspeCtive study to evaluate efficacy, safety and tOlerability of dietary supplemeNT of Curcumin (BCM95) in subjects with Active relapsing MultIple Sclerosis treated with subcutaNeous Interferon beta 1a 44 mcg TIW (CONTAIN): A randomized, controlled trial

Author

Petracca, Maria, Quarantelli, Mario, Moccia, Marcello, Vacca, Giovanni, Satelliti, Barbara, D'Ambrosio, Gianluigi, Carotenuto, Antonio, Ragucci, Monica, Assogna, Francesco, Capacchione, Antonio, Lanzillo, Roberta, and Morra, Vincenzo Brescia

Published
2021
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9. Neuroimaging in Nonsyndromic Craniosynostosis: Key Concepts to Unlock Innovation.

Author

Russo, Camilla, Aliberti, Ferdinando, Ferrara, Ursula Pia, Russo, Carmela, De Gennaro, Domenico Vincenzo, Cristofano, Adriana, Nastro, Anna, Cicala, Domenico, Spennato, Pietro, Quarantelli, Mario, Aiello, Marco, Soricelli, Andrea, Smaldone, Giovanni, Onorini, Nicola, De Martino, Lucia, Picariello, Stefania, Parlato, Stefano, Mirabelli, Peppino, Quaglietta, Lucia, and Covelli, Eugenio Maria

Subjects
MAGNETIC resonance angiography, MAGNETIC resonance, CRANIAL sutures, SYMPTOMS, TECHNOLOGICAL innovations
Abstract

Craniosynostoses (CRS) are caused by the premature fusion of one or more cranial sutures, with isolated nonsyndromic CRS accounting for most of the clinical manifestations. Such premature suture fusion impacts both skull and brain morphology and involves regions far beyond the immediate area of fusion. The combined use of different neuroimaging tools allows for an accurate depiction of the most prominent clinical–radiological features in nonsyndromic CRS but can also contribute to a deeper investigation of more subtle alterations in the underlying nervous tissue organization that may impact normal brain development. This review paper aims to provide a comprehensive framework for a better understanding of the present and future potential applications of neuroimaging techniques for evaluating nonsyndromic CRS, highlighting strategies for optimizing their use in clinical practice and offering an overview of the most relevant technological advancements in terms of diagnostic performance, radiation exposure, and cost-effectiveness. [ABSTRACT FROM AUTHOR]

Published
2024
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13. In vivo imaging of CNS microglial activation/macrophage infiltration with combined [18F]DPA-714-PET and SPIO-MRI in a mouse model of relapsing remitting experimental autoimmune encephalomyelitis

Author

Coda, A. R., Anzilotti, S., Boscia, F., Greco, A., Panico, M., Gargiulo, S., Gramanzini, M., Zannetti, A., Albanese, S., Pignataro, G., Annunziato, L., Salvatore, M., Brunetti, A., De Berardinis, P., Quarantelli, Mario, Palma, G., and Pappatà, Sabina

Published
2021
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16. 2D linear measures of ventricular enlargement may be relevant markers of brain atrophy and long-term disability progression in multiple sclerosis

Author

Pontillo, Giuseppe, Cocozza, Sirio, Di Stasi, Martina, Carotenuto, Antonio, Paolella, Chiara, Cipullo, Maria Brunella, Perillo, Teresa, Vola, Elena Augusta, Russo, Camilla, Masullo, Marco, Moccia, Marcello, Lanzillo, Roberta, Tedeschi, Enrico, Elefante, Andrea, Brescia Morra, Vincenzo, Brunetti, Arturo, Quarantelli, Mario, and Petracca, Maria

Published
2020
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22. Is proctoscopy sufficient for the evaluation of colorectal anastomosis prior to ileostomy reversal? A nationwide retrospective analysis of the Italian Society of Surgical Oncology Colorectal Cancer Network Collaborative group (SICO‐CCN).

Author

Manigrasso, Michele, Degiuli, Maurizio, Maione, Francesco, Venetucci, Pietro, Roviello, Franco, De Palma, Giovanni Domenico, Milone, Marco, Anoldo, Pietro, Vertaldi, Sara, Quarantelli, Mario, Reddavid, Rossella, Petronio, Nicoletta, Rizzo, Gianluca, Coco, Claudio, Amodio, Luca, Gallo, Gaetano, Sena, Giuseppe, Sammarco, Giuseppe, Sica, Giuseppe, and Siragusa, Leandro

Subjects
ILEOSTOMY, ONCOLOGIC surgery, COLORECTAL cancer, SURGICAL anastomosis, PROPENSITY score matching, RETROSPECTIVE studies
Abstract

Aim: Several methods for assessing anastomotic integrity have been proposed, but the best is yet to be defined. The aim of this study was to compare the different methods to assess the integrity of colorectal anastomosis prior to ileostomy reversal. Method: A retrospective cohort analysis on patients between 1 January 2010 and 31 December 2020 with a defunctioning stoma for middle and low rectal anterior resection was performed. A propensity score matching comparison between patients who underwent proctoscopy alone and patients who underwent proctoscopy plus any other preoperative method to assess the integrity of colorectal anastomosis prior to ileostomy reversal (transanal water‐soluble contrast enema via conventional radiology, transanal water‐soluble contrast enema via CT, and magnetic resonance) was performed. Results: The analysis involved 1045 patients from 26 Italian referral colorectal centres. The comparison between proctoscopy alone versus proctoscopy plus any other preoperative tool showed no significant differences in terms of stenoses (p = 0.217) or leakages (p = 0.103) prior to ileostomy reversal, as well as no differences in terms of misdiagnosed stenoses (p = 0.302) or leakages (p = 0.509). Interestingly, in the group that underwent proctoscopy and transanal water‐soluble contrast enema the comparison between the two procedures demonstrated no significant differences in detecting stenoses (2 vs. 0, p = 0.98), while there was a significant difference in detecting leakages in favour of transanal water‐soluble contrast enema via CT (3 vs. 12, p = 0.03). Conclusions: We can confirm that proctoscopy alone should be considered sufficient prior to ileostomy reversal. However, in cases in which the results of proctoscopy are not completely clear or the surgeon remains suspicious of an anastomotic leakage, transanal water‐soluble contrast enema via CT could guarantee its detection. [ABSTRACT FROM AUTHOR]

Published
2024
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27. A Blood Test for the Diagnosis of Multiple Sclerosis.

Author

Giuliano, Paola, La Rosa, Giuliana, Capozzi, Serena, Cassano, Emanuele, Damiano, Simona, Habetswallner, Francesco, Iodice, Rosa, Marra, Maurizio, Pavone, Luigi Michele, Quarantelli, Mario, Vitelli, Giuseppe, Santillo, Mariarosaria, and Paternò, Roberto

Subjects
SEROTONIN receptors, MULTIPLE sclerosis, BLOOD testing, ENZYME-linked immunosorbent assay, NEUROLOGICAL disorders, DIAGNOSIS, NATALIZUMAB
Abstract

Multiple sclerosis (MS) is an autoimmune chronic disease characterized by inflammation and demyelination of the central nervous system (CNS). Despite numerous studies conducted, valid biomarkers enabling a definitive diagnosis of MS are not yet available. The aim of our study was to identify a marker from a blood sample to ease the diagnosis of MS. In this study, since there is evidence connecting the serotonin pathway to MS, we used an ELISA (Enzyme-Linked Immunosorbent Assay) to detect serum MS-specific auto-antibodies (auto-Ab) against the extracellular loop 1 (ECL-1) of the 5-hydroxytryptamine (5-HT) receptor subtype 2A (5-HT2A). We utilized an ELISA format employing poly-D-lysine as a pre-coating agent. The binding of 208 serum samples from controls, both healthy and pathological, and of 104 serum samples from relapsing–remitting MS (RRMS) patients was tested. We observed that the serum-binding activity in control cohort sera, including those with autoimmune and neurological diseases, was ten times lower compared to the RRMS patient cohort (p = 1.2 × 10−47), with a sensitivity and a specificity of 98% and 100%, respectively. These results show that in the serum of patients with MS there are auto-Ab against the serotonin receptor type 2A which can be successfully used in the diagnosis of MS due to their high sensitivity and specificity. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Fully automated measurement of intracranial CSF and brain parenchyma volumes in pediatric hydrocephalus by segmentation of clinical MRI studies.

Author

Russo, Carmela, Pirozzi, Maria Agnese, Mazio, Federica, Cascone, Daniele, Cicala, Domenico, De Liso, Maria, Nastro, Anna, Covelli, Eugenio Maria, Cinalli, Giuseppe, and Quarantelli, Mario

Subjects
HYDROCEPHALUS, MAGNETIC resonance imaging, CEREBROSPINAL fluid, CEREBROSPINAL fluid examination, LIFTING & carrying (Human mechanics)
Abstract

Background: Brain parenchyma (BP) and intracranial cerebrospinal fluid (iCSF) volumes measured by fully automated segmentation of clinical brain MRI studies may be useful for the diagnosis and follow‐up of pediatric hydrocephalus. However, previously published segmentation techniques either rely on dedicated sequences, not routinely used in clinical practice, or on spatial normalization, which has limited accuracy when severe brain distortions, such as in hydrocephalic patients, are present. Purpose: We developed a fully automated method to measure BP and iCSF volumes from clinical brain MRI studies of pediatric hydrocephalus patients, exploiting the complementary information contained in T2‐ and T1‐weighted images commonly used in clinical practice. Methods: The proposed procedure, following skull‐stripping of the combined volumes, performed using a multiparametric method to obtain a reliable definition of the inner skull profile, maximizes the CSF‐to‐parenchyma contrast by dividing the T2w‐ by the T1w‐ volume after full‐scale dynamic rescaling, thus allowing separation of iCSF and BP through a simple thresholding routine. Results: Validation against manual tracing on 23 studies (four controls and 19 hydrocephalic patients) showed excellent concordance (ICC > 0.98) and spatial overlap (Dice coefficients ranging from 77.2% for iCSF to 96.8% for intracranial volume). Accuracy was comparable to the intra‐operator reproducibility of manual segmentation, as measured in 14 studies processed twice by the same experienced neuroradiologist. Results of the application of the algorithm to a dataset of 63 controls and 57 hydrocephalic patients (19 with parenchymal damage), measuring volumes' changes with normal development and in hydrocephalic patients, are also reported for demonstration purposes. Conclusions: The proposed approach allows fully automated segmentation of BP and iCSF in clinical studies, also in severely distorted brains, enabling to assess age‐ and disease‐related changes in intracranial tissue volume with an accuracy comparable to expert manual segmentation. [ABSTRACT FROM AUTHOR]

Published
2023
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35. Is advanced neuroimaging for neuroradiologists? A systematic review of the scientific literature of the last decade

Author

Cocozza, Sirio, Russo, Camilla, Pontillo, Giuseppe, Ugga, Lorenzo, Macera, Antonio, Cervo, Amedeo, De Liso, Maria, Di Paolo, Nilde, Ginocchio, Maria Isabella, Giordano, Flavio, Leone, Giuseppe, Rusconi, Giovanni, Stanzione, Arnaldo, Briganti, Francesco, Quarantelli, Mario, Caranci, Ferdinando, D’Amico, Alessandra, Elefante, Andrea, Tedeschi, Enrico, and Brunetti, Arturo

Published
2016
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