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Your search keyword '"Riva, Matteo"' showing total 240 results
Start Over Author "Riva, Matteo" Publication Type Academic Journals
240 results on '"Riva, Matteo"'

1. YY1 mutations disrupt corticogenesis through a cell type specific rewiring of cell-autonomous and non-cell-autonomous transcriptional programs

Author

Pereira, Marlene F., Finazzi, Veronica, Rizzuti, Ludovico, Aprile, Davide, Aiello, Vittorio, Mollica, Luca, Riva, Matteo, Soriani, Chiara, Dossena, Francesco, Shyti, Reinald, Castaldi, Davide, Tenderini, Erika, Carminho-Rodrigues, Maria Teresa, Bally, Julien F., de Vries, Bert B. A., Gabriele, Michele, Vitriolo, Alessandro, and Testa, Giuseppe

Published
2025
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6. GPR162 is a beta cell CART receptor

Author

Lindqvist, Andreas, Abels, Mia, Shcherbina, Liliya, Ngara, Mtakai, Kryvokhyzha, Dmytro, Chriett, Sabrina, Riva, Matteo, Fajul, Abul, Barghouth, Mohammad, Luan, Cheng, Eliasson, Lena, Larsen, Olav, Rosenkilde, Mette M., Zhang, Enming, Renström, Erik, and Wierup, Nils

Published
2023
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10. Selective Cerebrospinal Fluid Hypothermia: Bioengineering Development and In Vivo Study of an Intraventricular Cooling Device (V-COOL)

Author

Beretta, Simone, Versace, Alessandro, Fiore, Gianfranco, Piola, Marco, Martini, Beatrice, Bigiogera, Vittorio, Coppadoro, Lorenzo, Mariani, Jacopo, Tinti, Lorenzo, Pirovano, Silvia, Monza, Laura, Carone, Davide, Riva, Matteo, Padovano, Giada, Galbiati, Gilda, Santangelo, Francesco, Rasponi, Marco, Padelli, Francesco, Giachetti, Isabella, Aquino, Domenico, Diamanti, Susanna, Librizzi, Laura, Bruzzone, Maria Grazia, De Curtis, Marco, Giussani, Carlo, Sganzerla, Erik P., and Ferrarese, Carlo

Published
2022
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20. Multi-parameter perturbations for the space-periodic heat equation.

Author

Riva, Matteo Dalla, Luzzini, Paolo, Molinarolo, Riccardo, and Musolino, Paolo

Subjects
HEAT transfer, NONLINEAR operators
Abstract

This paper is divided into three parts. The first part focuses on periodic layer heat potentials, demonstrating their smooth dependence on regular perturbations of the support of integration. In the second part, we present an application of the results from the first part. Specifically, we consider a transmission problem for the heat equation in a periodic domain and we show that the solution depends smoothly on the shape of the transmission interface, boundary data, and transmission parameters. Finally, in the last part of the paper, we fix all parameters except for the transmission parameters and outline a strategy to deduce an explicit expansion of the solution using Neumann-type series. [ABSTRACT FROM AUTHOR]

Published
2024
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23. CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion

Author

Abels, Mia, Riva, Matteo, Bennet, Hedvig, Ahlqvist, Emma, Dyachok, Oleg, Nagaraj, Vini, Shcherbina, Liliya, Fred, Rikard G., Poon, Wenny, Sörhede-Winzell, Maria, Fadista, Joao, Lindqvist, Andreas, Kask, Lena, Sathanoori, Ramasri, Dekker-Nitert, Marloes, Kuhar, Michael J., Ahrén, Bo, Wollheim, Claes B., Hansson, Ola, Tengholm, Anders, Fex, Malin, Renström, Erik, Groop, Leif, Lyssenko, Valeriya, and Wierup, Nils

Published
2016
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26. Preclinical studies performed in appropriate models could help identify optimal timing of combined chemotherapy and immunotherapy.

Author

Berckmans, Yani, Ceusters, Jolien, Vankerckhoven, Ann, Wouters, Roxanne, Riva, Matteo, and Coosemans, An

Subjects
IMMUNE checkpoint inhibitors, CANCER chemotherapy, IMMUNOTHERAPY, CANCER treatment, SCIENTIFIC models
Abstract

Immune checkpoint inhibitors (ICI) have been revolutionary in the field of cancer therapy. However, their success is limited to specific indications and cancer types. Recently, the combination treatment of ICI and chemotherapy has gained more attention to overcome this limitation. Unfortunately, many clinical trials testing these combinations have provided limited success. This can partly be attributed to an inadequate choice of preclinical models and the lack of scientific rationale to select the most effective immune-oncological combination. In this review, we have analyzed the existing preclinical evidence on this topic, which is only limitedly available. Furthermore, this preclinical data indicates that besides the selection of a specific drug and dose, also the sequence or order of the combination treatment influences the study outcome. Therefore, we conclude that the success of clinical combination trials could be enhanced by improving the preclinical set up, in order to identify the optimal treatment combination and schedule to enhance the anti-tumor immunity. [ABSTRACT FROM AUTHOR]

Published
2023
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27. A Degenerating Robin-Type Traction Problem in a Periodic Domain.

Author

Dalla Riva, Matteo, Mishuris, Gennady, and Musolino, Paolo

Subjects
*POWER series, *MATRIX functions, *BOUNDARY value problems, *INTEGRAL operators, *INTEGRAL equations, *GENTRIFICATION
Abstract

We consider a linearly elastic material with a periodic set of voids. On the boundaries of the voids we set a Robin-type traction condition. Then, we investigate the asymptotic behavior of the displacement solution as the Robin condition turns into a pure traction one. To wit, there will be a matrix function b[k](·) that depends analytically on a real parameter k and vanishes for k = 0 and we multiply the Dirichlet-like part of the Robin condition by b[k](·). We show that the displacement solution can be written in terms of power series of k that converge for k in a whole neighborhood of 0. For our analysis we use the Functional Analytic Approach. [ABSTRACT FROM AUTHOR]

Published
2023
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32. Head down tilt 15° to preserve salvageable brain tissue in acute ischemic stroke: A pre‐clinical pooled analysis, with focus on cerebral hemodynamics.

Author

Diamanti, Susanna, Mariani, Jacopo, Versace, Alessandro, Riva, Matteo, Cuccione, Elisa, Cai, Ruiyao, Monza, Laura, Viganò, Martina, Bolbos, Radu, Chauveau, Fabien, Cho, Tae‐Hee, Carone, Davide, Ferrarese, Carlo, and Beretta, Simone

Subjects
ISCHEMIC stroke, HEMODYNAMICS, ARTERIAL occlusions, CEREBRAL arteries
Abstract

Neurological outcome after ischemic stroke depends on residual salvageable brain tissue at the time of recanalization. Head down tilt 15° (HDT15) was proven effective in reducing infarct size and improving functional outcome in rats with transient middle cerebral artery occlusion (t‐MCAO) by increasing cerebral perfusion within the ischemic penumbra. In this pooled analysis, individual animal‐level data from three experimental series were combined in a study population of 104 t‐MCAO rats (45 in HDT15 group and 59 in flat position group). Co‐primary outcomes were infarct size and functional outcome at 24 h in both groups. The secondary outcome was hemodynamic change induced by HDT15 in ischemic and non‐ischemic hemispheres in a subgroup of animals. Infarct size at 24 h was smaller in HDT15 group than in flat position group (absolute mean difference 31.69 mm3, 95% CI 9.1–54.2, Cohen's d 0.56, p = 0.006). Functional outcome at 24 h was better in HDT15 group than in flat position group (median [IQR]: 13[10–16] vs. 11), with a shift in the distribution of the neurobehavioural scores in favour of HDT15. Mean cerebral perfusion in the ischemic hemisphere was higher during HDT15 than before its application (Perfusion Unit [P.U.], mean ± SD: 52.5 ± 19.52 P.U. vs. 41.25 ± 14.54 P.U., mean of differences 13.36, 95% CI 7.5–19.18, p = 0.0002). Mean cerebral perfusion in the non‐ischemic hemisphere before and during HDT15 was unchanged (P.U., mean ± SD: 94.1 ± 33.8 P.U. vs. 100.25 ± 25.34 P.U., mean of differences 3.95, 95%, CI −1.9 to 9.6, p = 0.1576). This study confirmed that HDT15 improves the outcome in t‐MCAO rats by promoting cerebral perfusion in the ischemic territory, without disrupting hemodynamics in non‐ischemic areas. [ABSTRACT FROM AUTHOR]

Published
2023
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33. Singular behavior for a multi-parameter periodic Dirichlet problem.

Author

Dalla Riva, Matteo, Luzzini, Paolo, and Musolino, Paolo

Subjects
*DIRICHLET problem, *ANALYTIC mappings, *REAL numbers, *POISSON'S equation, *RADIUS (Geometry), *BANACH spaces, *GEOMETRY
Abstract

We consider a Dirichlet problem for the Poisson equation in a periodically perforated domain. The geometry of the domain is controlled by two parameters: a real number ϵ > 0 , proportional to the radius of the holes, and a map ϕ, which models the shape of the holes. So, if g denotes the Dirichlet boundary datum and f the Poisson datum, we have a solution for each quadruple (ϵ , ϕ , g , f). Our aim is to study how the solution depends on (ϵ , ϕ , g , f) , especially when ϵ is very small and the holes narrow to points. In contrast with previous works, we do not introduce the assumption that f has zero integral on the fundamental periodicity cell. This brings in a certain singular behavior for ϵ close to 0. We show that, when the dimension n of the ambient space is greater than or equal to 3, a suitable restriction of the solution can be represented with an analytic map of the quadruple (ϵ , ϕ , g , f) multiplied by the factor 1 / ϵ n − 2 . In case of dimension n = 2 , we have to add log ϵ times the integral of f / 2 π. [ABSTRACT FROM AUTHOR]

Published
2023
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46. Existence results for a nonlinear nonautonomous transmission problem via domain perturbation.

Author

Dalla Riva, Matteo, Molinarolo, Riccardo, and Musolino, Paolo

Subjects
BOUNDARY value problems, DIFFERENTIAL inclusions, NONLINEAR operators
Abstract

In this paper we study the existence and the analytic dependence upon domain perturbation of the solutions of a nonlinear nonautonomous transmission problem for the Laplace equation. The problem is defined in a pair of sets consisting of a perforated domain and an inclusion whose shape is determined by a suitable diffeomorphism $\phi$. First we analyse the case in which the inclusion is a fixed domain. Then we will perturb the inclusion and study the arising boundary value problem and the dependence of a specific family of solutions upon the perturbation parameter $\phi$. [ABSTRACT FROM AUTHOR]

Published
2022
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47. Shape analyticity and singular perturbations for layer potential operators.

Author

Dalla Riva, Matteo, Luzzini, Paolo, and Musolino, Paolo

Subjects
*SINGULAR perturbations, *POWER series, *ZETA potential, *OPERATOR equations, *NONLINEAR operators
Abstract

We study the effect of regular and singular domain perturbations on layer potential operators for the Laplace equation. First, we consider layer potentials supported on a diffeomorphic image ϕ(∂Ω) of a reference set ∂Ω and we present some real analyticity results for the dependence upon the map ϕ. Then we introduce a perforated domain Ω(ε) with a small hole of size ε and we compute power series expansions that describe the layer potentials on ∂Ω(ε) when the parameter ε approximates the degenerate value ε = 0. [ABSTRACT FROM AUTHOR]

Published
2022
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