1. Echocardiographically defined haemodynamic categorization predicts prognosis in ambulatory heart failure patients treated with sacubitril/valsartan
- Author
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Frank L. Dini, Erberto Carluccio, Roberto Bitto, Michele Ciccarelli, Michele Correale, Andreina D'Agostino, Giuseppe Dattilo, Marco Ferretti, Arianna Grelli, Stefania Guida, Francesca Jacoangeli, Laura Lupi, Lorenzo Luschi, Daniele Masarone, Valentina Mercurio, Giuseppe Pacileo, Nicola Riccardo Pugliese, Antonella Rispoli, Laura Scelsi, Carlo Gabriele Tocchetti, Natale Daniele Brunetti, Alberto Palazzuoli, Massimo Piepoli, Savina Nodari, Giuseppe Ambrosio, and Working Group on Heart Failure of the Italian Society of Cardiology
- Subjects
heart failure ,ejection fraction ,haemodynamic ,prognosis ,sacubitril/valsartan ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Aim Echo‐derived haemodynamic classification, based on forward‐flow and left ventricular (LV) filling pressure (LVFP) correlates, has been proposed to phenotype patients with heart failure and reduced ejection fraction (HFrEF). To assess the prognostic relevance of baseline echocardiographically defined haemodynamic profile in ambulatory HFrEF patients before starting sacubitril/valsartan. Methods and results In our multicentre, open‐label study, HFrEF outpatients were classified into 4 groups according to the combination of forward flow (cardiac index; CI:< or ≥2.0 L/min/m2) and early transmitral Doppler velocity/early diastolic annular velocity ratio (E/e′: ≥ or
- Published
- 2022
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