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At the cornerstone of the pelvis and spine, the sacrum may be fractured in patients of all ages. Sacral fractures range from high-energy injuries, with mortality rates of up to 18%, to low-energy insufficiency fractures. The intricate geometry of the sacrum, the breadth of morphotypes, and the presence of congenital anomalies all can complicate the treatment of these fractures. Agreement on the surgical indications for these injuries is limited. This narrative review aims to update orthopedic surgeons on the clinical evaluation and the non-surgical and surgical management of these fractures. [ABSTRACT FROM AUTHOR]

Abstract Background Iliosacral screw fixation is safe and effective but can be complicated by loss of fixation, particularly in patients with osteopenic bone. Sacral morphology dictates where iliosacral screws may be placed when stabilizing pelvic ring injuries. In dysmorphic sacra, the safe osseous corridor of the upper sacral segment (S1) is smaller and lacks a transsacral corridor, increasing the need for fixation in the second sacral segment (S2). Previous evidence suggests that S2 is less dense than S1. The aim of this cross-sectional study is to further evaluate bone mineral density (BMD) of the S1 and S2 iliosacral osseous pathways through morphology stratification into normal and dysmorphic sacra. Materials and methods Pelvic computed tomography scans of 50 consecutive trauma patients, aged 18 to 50 years, from a level 1 trauma center were analyzed prospectively. Five radiographic features (upper sacral segment not recessed in the pelvis, mammillary bodies, acute alar slope, residual S1 disk, and misshapen sacral foramen) were used to identify dysmorphic characteristics, and sacra with four or five features were classified as dysmorphic. Hounsfield unit values were used to estimate the regional BMD of S1 and S2. Student’s t-test was utilized to compare the mean values at each segment, with statistical significance being set at p

Abstract Background Exact knowledge of the sacral anatomy is crucial for the percutaneous insertion of iliosacral screws. However, dysplastic anatomical patterns are common. In addition to a preoperative computed tomography (CT) analysis, conventional radiographic measures may help to identify upper sacral dysplasia and to avoid damage to surrounding structures. Aiming to further increase safety in percutaneous iliosacral screw placement in the presence of sacral dysmorphism, this study examined the prevalence of previously established radiographic signs and, in addition, defined the “critical SI angle” as a new radiographic criterion. Methods Pelvic CT scans of 98 consecutive trauma patients were analysed. Next to assessment of established signs indicating upper sacral dysplasia, the critical sacroiliac (SI) angle was defined in standardized pelvic outlet views. Results The critical SI angle significantly correlates with the presence of mammillary bodies and an intraarticular vacuum phenomenon. With a cut-off value of − 14.2°, the critical SI angle detects the feasibility of a safe iliosacral screw insertion in pelvic outlet views with a sensitivity of 85.9% and a specificity of 85.7%. Conclusions The critical SI angle can support the decision-making when planning iliosacral screw fixation. The clinical value of the established signs of upper sacral dysplasia remains uncertain.

Background: Iliosacral screw fixation is safe and effective but can be complicated by loss of fixation, particularly in patients with osteopenic bone. Sacral morphology dictates where iliosacral screws may be placed when stabilizing pelvic ring injuries. In dysmorphic sacra, the safe osseous corridor of the upper sacral segment (S1) is smaller and lacks a transsacral corridor, increasing the need for fixation in the second sacral segment (S2). Previous evidence suggests that S2 is less dense than S1. The aim of this cross-sectional study is to further evaluate bone mineral density (BMD) of the S1 and S2 iliosacral osseous pathways through morphology stratification into normal and dysmorphic sacra.Materials and Methods: Pelvic computed tomography scans of 50 consecutive trauma patients, aged 18 to 50 years, from a level 1 trauma center were analyzed prospectively. Five radiographic features (upper sacral segment not recessed in the pelvis, mammillary bodies, acute alar slope, residual S1 disk, and misshapen sacral foramen) were used to identify dysmorphic characteristics, and sacra with four or five features were classified as dysmorphic. Hounsfield unit values were used to estimate the regional BMD of S1 and S2. Student's t-test was utilized to compare the mean values at each segment, with statistical significance being set at p < 0.05. No change in clinical management occurred as a result of inclusion in this study.Results: A statistical difference in BMD was appreciated between S1 and S2 in both normal and dysmorphic sacra (p < 0.0001), with 28.4% lower density in S2 than S1. Further, S1 in dysmorphic sacra tended to be 4% less dense than S1 in normal sacra (p = 0.047). No difference in density was appreciated at S2 based on morphology.Conclusions: Our results would indicate that, based on BMD alone, fixation should be maximized in S1 prior to fixation in S2. In cases where S2 fixation is required, we recommend that transsacral fixation should be strongly considered if possible to bypass the S2 body and achieve fixation in the cortical bone of the ilium and sacrum.Level Of Evidence: Level III. [ABSTRACT FROM AUTHOR]

Study Design: Retrospective radioanatomic single-center cohort study.Objective: To investigate sex-specific differences in transsacral corridor dimensions, determine feasibility rates of transsacral screw placement without extended safety zones around planned screw positions, and develop an index defining sacral dysmorphism (SD) irrespective of transsacral corridor diameters.Summary Of Background Data: Previously reported SD definitions used radiologically identifiable pelvic characteristics or predefined minimum diameter thresholds of transsacral corridors in the upper sacral segment including safety zones for screw placement. Technical progress of surgical 3D image guidance improved sacral screw insertion accuracy questioning established minimum diameter threshold-based SD definitions.Methods: Datasets from cross-sectional pelvic imaging of 100 women and 100 men presenting to a general hospital from July 2018 through August 2018 were included in a database to evaluate transsacral trajectory rates, and dimensions of transsacral corridor lengths, widths (TSCWs), and heights (TSCHs) in sacral segments I to III (S1-3). SD was assumed, if no transsacral trajectory was found in S1 with a corridor diameter of at least 7.5 mm.Results: Women presented significantly higher rates of transsacral trajectories in the inferior sector of S1 (P = 0.03), and larger transsacral corridor lengths in S2 (superior sector, P = 0.045), and S3 (central position, P = 0.02). In men, significantly higher feasibility rates were found for the placement of two transsacral screws in S2 (P = 0.0002), and singular screws in S3 (P = 0.006), with larger S1- (P = 0.0002), and central S2-TSCWs (P = 0.006). SD was prevalent in 17% of women, and 16% of men (P = 0.85). Calculating TSCW ratios of S1 and S2 was significantly indicative for SD at values below a threshold of 0.8 in women (P < 0.00001), and men (P = 0.0004).Conclusion: SD is independent of sex despite significant differences in sacral morphology. An index defining SD irrespective of absolute transsacral corridor dimensions is presented to reliably differentiate dysmorphic from nondysmorphic sacra in women and men.Level Of Evidence: 2. [ABSTRACT FROM AUTHOR]

ABSTRACT Variations in sacral segmentation may preclude safe placement of transsacral screws for posterior pelvis fixation. We developed a novel automated 3D technique to determine the safe zone size for transsacral screws in the upper two sacral segments in 526 adult pelvis computed tomography scans. Safe zone sizes were then compared by gender and sacral segmentation variations (number of neuroforamen and the presence/absence of lumbosacral transitional vertebrae, ±LSTV). Ten millimeters was used as the safety threshold for a large screw. 3 (0.6%), 366 (70%), and 157 (30%) sacra had 3, 4, or 5 neuroforamen, respectively. Eighty-eight (17%) were +LSTV. Safe zone size depended on gender, number of neuroforamen in −LSTV sacra and presence of LSTV ( p < 0.001) but not on the uni- or bilateral nature of the LSTV. 17% of −LSTV sacra were below the safety threshold in S1, 27% in S2, whereas 3% of +LSTV sacra were below in S1, 74% in S2. Of −LSTV sacra that cannot take an S1 screw safely, 77% can do so in S2, leaving only 4% of sacra that cannot accommodate a screw safely in either upper segment. The results demonstrate a predictable pattern of safe zone size based on gender and sacral segmentation variations. © 2014 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:277-282, 2015. [ABSTRACT FROM AUTHOR]

Background: Recent studies of iliosacral screw fixation performed using intraoperative navigation systems have shown promising results. The Surgivisio Platform is a new-generation three-dimensional intraoperative navigation tool that has been used at our institution for 2years. The aim of this prospective study was to assess the contribution of navigation in terms of iliosacral screw positioning accuracy and of radiation exposure, by comparing outcomes with vs. without navigation., Hypothesis: Navigation allows more accurate percutaneous iliosacral screw positioning regardless of the type of screw fixation (with sacral dysmorphism and/or cemented screw fixation and/or multiple screw fixation)., Materials and Methods: Between January 2018 and December 2019, consecutive patients who underwent percutaneous iliosacral screw fixation of pelvic ring fractures without vertical instability were included in this single-centre prospective study. Screw position accuracy was evaluated by postoperative high-resolution computed tomography (HRCT). Operative time, radiation dose, and complications were recorded., Results: We included 127 patients with 174 iliosacral screws, of which 129 were positioned under fluoroscopic guidance and 45 using navigation. According to the modified Gras classification, 7% (12/174) of the screws were incorrectly positioned and 2% (4/174) required repositioning. The frequency of screw malposition was not significantly different between the fluoroscopy and navigation groups (8.5%, 11/129 vs. 2.2%, 1/45, respectively; p=0.19). However, screw position in dysmorphic sacra was significantly better with navigation (p=0.04), whereas no significant difference in final screw position was found for cemented or multiple screw implantations. In the navigation group, the operative time was significantly longer (28.2min vs. 21.6min, p=0.003), and the mean dose-area product significantly greater (6.6Gy·cm 2 vs. 4.9Gy·cm 2 , p=0.02). The complication rates were not different between the two groups., Conclusion: In patients who have pelvic ring fractures without vertical instability, navigation of percutaneous iliosacral screw placement using the Surgivisio Platform improves screw positioning in dysmorphic sacra, at the cost of a longer operative time and greater radiation exposure of the patient., Level of Evidence: II, prospective study., (Copyright © 2022 Elsevier Masson SAS. All rights reserved.)

Objectives: To investigate the characteristics of iliosacral (IS) screw corridors of Japanese pelves., Methods: Computer tomography images of 42 adult Japanese subjects without any pelvic injury were analyzed at a workstation. Using the manual reconstruction function, the width of a simulated horizontal corridor for an IS screw on the true coronal and true axial planes in the upper (S1), second (S2), and the third (S3) sacral segments was measured. For pelves without an adequate S1 corridor, a cranially tilted corridor was sought. A corridor was defined as "adequate" if its width on both planes was 10 mm or more., Results: An adequate horizontal corridor was found in S1 in 17 (40.5%) subjects, in S2 in 29 (69.0%) subjects, and in S3 in no subject. An independent factor affecting the adequacy of the S1 corridor was the adequacy of the S2 corridor (OR: 0.09). Similarly, an independent factor affecting S2 adequacy was S1 adequacy (OR: 0.10). A tilted, 10 mm diameter corridor was found in all 25 subjects who did not have an adequate horizontal corridor in the S1 segment. The angle required to obtain a 10 mm diameter corridor inversely correlated with the diameter of a horizontal corridor on the true coronal plane (R = -0.713, P  = .000)., Conclusions: The characteristics of IS screw corridors in the 42 Japanese subjects were similar to those reported in previous studies conducted in the West. The importance of preoperative planning using reliable techniques, such as three-dimensional reconstruction, should be emphasized.Level of evidence: Diagnostic Level III. See Instructions for Authors for a complete description of level of evidence., Competing Interests: The author has no conflicts of interest to disclose., (Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Orthopaedic Trauma Association.)

Background: Anatomic variation in the relationship between the lumbar spine and sacrum was first described in the literature nearly a century ago and continues to play an important role in spine deformity, low back pain (LBP), and pelvic trauma. This review will focus on the clinical and surgical implications of abnormal lumbosacral anatomy in the context of sacroiliac joint (SIJ) disease, spine deformity, and pelvic trauma., Methods: A PubMed search using the keywords "lumbosacral transitional vertebrae," "LSTV," "transitional lumbosacral vertebrae," "TLSV," and "sacral dysmorphism" was performed. The articles presented here were evaluated by the authors., Clinical Significance: The prevalence of LSTV varies widely in the literature from 3.9-% to 35.6% in the spine literature, and sacral dysmorphism is described in upwards of 50% of the population in the trauma literature. The relationship between LSTV and LBP is well established. While there is no agreed-on etiology, the source of pain is multifactorial and may be related to abnormal biomechanics and alignment, disc degeneration, and arthritic changes., Surgical Implications: Understanding abnormal lumbosacral anatomy is crucial for preoperative planning of SIJ fusion, spine deformity, and pelvic trauma surgery. LSTV can alter spinopelvic parameters crucial in planning spine deformity correction. Traditional safe zones for sacroiliac screw placement do not apply in the first sacral segment in sacral dysmorphism and risk iatrogenic nerve injury., Conclusions: LSTV and sacral dysmorphism are common anatomic variants found in the general population. Abnormal lumbosacral anatomy plays a significant role in clinical evaluation of LBP and surgical planning in SIJ fusion, spine deformity, and pelvic trauma. Further studies evaluating the influence of abnormal lumbosacral anatomy on LBP and surgical technique would help guide treatment for these patients., Competing Interests: Disclosures and COI: Each author certifies that he or she has no commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted work. This paper is exempt from institutional review board review, as it is not human subjects research. There was no external source of funding for this study., (©International Society for the Advancement of Spine Surgery 2020.)