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Your search keyword '"Schena, F.P."' showing total 67 results
Start Over Author "Schena, F.P." Publication Type Academic Journals
67 results on '"Schena, F.P."'

28. Effect of Fibronectin on C3b and Fc Receptor-mediated Phagocytosis by Peripheral Blood Monocytes in Uraemic Patients.

Author

Pertosa, G., Mastrolitti, R.T., Späth, P.J., Fracasso, A.R., Manno, C., and Schena, F.P.

Abstract

The influence of human fibronectin was evaluated on the phagocytosis in vitro of (C3b receptor-mediated) and IgG antibody-coated sheep erythrocytes .(Fc receptor-mediated) by the peripheral blood monocytes of 40 uraemic patients undergoing periodic haemodialysis. Some nutritional parameters (albumin, transferrin, C4, C3, haematocrit, lymphocyte count, height and bodyweight) were also evaluated. Results showed significantly decreased plasma fibronectin (<0.001) and reduced C3b receptor (R)- and FcR-mediated phagocytosis in uraemic patients (<0.001). A strict correlation was found between fibronectin and C3bR-mediated phagocytosis (<0.001) and between fibronectin and FcR-mediated phagocytosis (<0.05). In 20 patients with decreased fibronectin concentrations and reduced phagocytic function, the in vitro incubation of peripheral blood monocytes with 50 μg/ml of purified fibronectin significantly enhanced C3bR- (<0.001) but not FcR-mediated phagocytosis. Study of nutritional parameters in the uraemic patients revealed that values of fibronectin, C3, IgG and albumin were significantly reduced. Fibronectin correlated significantly (<0.00l) with C3. A good relationship (<0.05) was also found between the plasma fibronectin and bodyweight loss. A greater incidence of infectious disease was observed in patients with decreased plasma fibronectin than in uraemic patients with normal values (<0.05). The results suggest that a decrease in plasma fibronectin in uraemic patients could impair the peripheral blood monocyte phagocytic capacity and be potentially dangerous, predisposing the patient to infections. The determination of fibronectin concentration in these patients may, therefore, have a potential value as an indicator of peripheral blood mono cyte phagocytic function. [ABSTRACT FROM PUBLISHER]

Published
1989

41. Literature Abstracts.

Author

Gharavi, A.G., Yan, Y., Scolari, F., Schena, F.P., Frasca, G.M., Ghiggeri, G.M., Cooper, K., Amoroso, A., Viola, B.F., Battini, G., Caridi, G., Canova, C., Farhi, A., Subramanian, V., Nelson-Williams, C., Woodword, S., Julian, B.A., Wyatt, R.J., and Lifton, R.P.

Subjects
KIDNEY diseases, IGA glomerulonephritis, KIDNEY calcification, HYPERCALCIUREA
Abstract

Presents abstracts of article concerning kidney diseases, featured in the 2001 issue of the periodical 'Pediatric Nephrology.' Linkage of immunoglobulin A nephropathy and 6q22-23; Characteristics of hypomagnesemia-hypercalciuria-nephrocalcinosis.

Published
2001

42. Comparison of pathologic and normal sera by immune complex determination: Five disease groups within 190 samples are discriminated by computer-selected combinations of 13 methods: Report of the Italian committee for the study of immune complexes (WIC)

Author

Migliorini, Paola, Aiuti, F., Balestrieri, G., Bombardieri, S., Cantarella, Sebastiana, Carbonara, A., Clerici, E., Coppo, Rosanna, Cordiali Fei, Paola, D'Amelio, R., Del Giacco, G.S., Di Mario, U., Manca, F., Manno, C., Marchi, M., Massai, Graziella, Natali, P.G., Passaleva, A., isini, A., Pastore, Rosella, Rossi, G., Schena, F.P., Tincani, Angela, Trovatello, G., Valesini, G., and Celada, F.

Published
1984
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