482 results on '"Silke, John"'
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2. Brief Notices
3. RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation
4. Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency
5. Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity
6. The Celtic Monk: Rules and Writings of Early Irish Monks by Uinseann Ó Maidín, O.C.R. (review)
7. Priests and Prelates of Armagh in the Age of Reformations, 1518-1558 by Henry A. Jefferies (review)
8. The Cistercian Abbeys of Tipperary by Colmcille Ó Conbhuidhe, OCSO (review)
9. Blocking cell death limits lung damage and inflammation from influenza
10. RIPK1 and necroptosis role in premature ageing
11. A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation
12. The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family
13. Irlanda y el Rey Prudente and: An Irish Prisoner of Conscience in the Tudor Era: Archbishop Richard Creagh of Armagh, 1523-1586 (review)
14. Apoptotic cell death in disease—Current understanding of the NCCD 2023
15. MLKL deficiency protects against low-grade, sterile inflammation in aged mice
16. High molecular weight hyaluronic acid drastically reduces chemotherapy-induced mucositis and apoptotic cell death
17. Deletion of Gpatch2 does not alter Tnf expression in mice
18. Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease
19. OXTRHigh stroma fibroblasts control the invasion pattern of oral squamous cell carcinoma via ERK5 signaling
20. Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms
21. Dual roles for LUBAC signaling in thymic epithelial cell development and survival
22. Unleashing TNF cytotoxicity to enhance cancer immunotherapy
23. The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL
24. Clinical MDR1 inhibitors enhance Smac-mimetic bioavailability to kill murine LSCs and improve survival in AML models
25. Transplantable programmed death ligand 1 expressing gastroids from gastric cancer prone Nfkb1−/− mice
26. Telemedical cardiac risk assessment by implantable cardiac monitors in patients after myocardial infarction with autonomic dysfunction (SMART-MI-DZHK9): a prospective investigator-initiated, randomised, multicentre, open-label, diagnostic trial
27. Targeting triple-negative breast cancers with the Smac-mimetic birinapant
28. Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease
29. The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis
30. The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis
31. Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation
32. Determination of Cell Survival by RING-Mediated Regulation of Inhibitor of Apoptosis (IAP) Protein Abundance
33. Apaf-1 and Caspase-9 Accelerate Apoptosis, but Do Not Determine Whether Factor-Deprived or Drug-Treated Cells Die
34. Engineered Exosomes as Vehicles for Biologically Active Proteins
35. The Anti-Apoptotic Activity of XIAP Is Retained upon Mutation of Both the Caspase 3- and Caspase 9-Interacting Sites
36. ‘Did He Who Made the Lamb Make Thee?’ New Developments in Treating the ‘Fearful Symmetry’ of Acute Myeloid Leukemia
37. MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
38. A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction
39. DIABLO Promotes Apoptosis by Removing MIHA/XIAP from Processed Caspase 9
40. cIAPs control RIPK1 kinase activity‐dependent and ‐independent cell death and tissue inflammation.
41. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
42. Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted
43. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
44. The importance of being chaperoned: HSP90 and necroptosis
45. Addendum: A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs
46. A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs
47. LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L
48. Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis
49. Cellular inhibitor of apoptosis proteins prevent clearance of hepatitis B virus
50. Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
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