1. Stimulating autoantibodies directed against the cardiac [beta].sub.1-adrenergic receptor predict increased mortality in idiopathic cardiomyopathy
- Author
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Stork, Stefan, Boivin, Valerie, Horf, RuDiger, Hein, Lutz, Lohse, Martin J., Angermann, Christiane E., and Jahns, Roland
- Subjects
Cardiac patients -- Prognosis ,Cardiac patients -- Health aspects ,Heart failure -- Prognosis ,Heart failure -- Health aspects ,Autoimmunity -- Health aspects ,Autoantibodies -- Health aspects ,Mortality ,Health - Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ahj.2006.05.004 Byline: Stefan Stork (a), Valerie Boivin (b), Rudiger Horf (a), Lutz Hein (b), Martin J. Lohse (b), Christiane E. Angermann (a), Roland Jahns (a)(b) Abstract: The aim of this study was to estimate the independent and incremental prognostic value of the presence of stimulating autoantibodies directed against the human [beta].sub.1-adrenergic receptor (anti-[beta].sub.1-AR) in patients with chronic heart failure. Author Affiliation: (a) Department of Internal Medicine I / Center of Cardiovascular Medicine, University of Wurzburg, Wurzburg, Germany (b) Institute of Pharmacology and Toxicology, University of Wurzburg, Wurzburg, Germany Article History: Received 12 January 2006; Accepted 2 May 2006 Article Note: (footnote) Funding source: Deutsche Forschungsgemeinschaft, Grant Ja 706/2-4; Ernst und Berta Grimmke Stiftung, Dusseldorf, Germany.
- Published
- 2006