8 results on '"Thomas, Chantelle"'
Search Results
2. “One of those things the student is left to do”. Student midwives' experience of infant feeding education. A phenomenological study
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Spencer, Rachael Louise, Stephenson, Jane, and Thomas, Chantelle
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- 2022
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3. Pharmacokinetics of Escalating Doses of Oral Psilocybin in Healthy Adults
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Brown, Randall T., Nicholas, Christopher R., Cozzi, Nicholas V., Gassman, Michele C., Cooper, Karen M., Muller, Daniel, Thomas, Chantelle D., Hetzel, Scott J., Henriquez, Kelsey M., Ribaudo, Alexandra S., and Hutson, Paul R.
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- 2017
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4. High dose psilocybin is associated with positive subjective effects in healthy volunteers.
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Nicholas, Christopher R., Henriquez, Kelsey M., Gassman, Michele C., Cooper, Karen M., Muller, Daniel, Hetzel, Scott, Brown, Randall T., Cozzi, Nicholas V., Thomas, Chantelle, and Hutson, Paul R.
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PSILOCYBIN ,MENTAL depression ,QUALITY of life ,ANXIETY ,MEDICAL care ,COMPARATIVE studies ,DOSE-effect relationship in pharmacology ,HALLUCINOGENIC drugs ,LONGITUDINAL method ,RESEARCH methodology ,MEDICAL cooperation ,ORAL drug administration ,QUESTIONNAIRES ,RELIGION ,RESEARCH ,RESEARCH funding ,SATISFACTION ,TIME ,EVALUATION research ,PHARMACODYNAMICS - Abstract
Aim: The aim of the current study was to investigate the relationship between escalating higher doses of psilocybin and the potential psilocybin occasioned positive subjective effects.Methods: Healthy participants ( n=12) were given three escalating doses of oral psilocybin (0.3 mg/kg; 0.45 mg/kg; 0.6 mg/kg) or (18.8-36.6 mg; 27.1-54.0 mg; 36.3-59.2 mg) a minimum of four weeks apart in a supervised setting. Blood and urine samples, vital signs, and electrocardiograms were obtained. Subjective effects were assessed using the Mystical Experience Questionnaire and Persisting Effects Questionnaire.Results: There was a significant linear dose-related response in Mystical Experience Questionnaire total score and the transcendence of time and space subscale, but not in the rate of a complete mystical experience. There was also a significant difference between dose 3 compared to dose 1 on the transcendence of time and space subscale, while no dose-related differences were found for Mystical Experience Questionnaire total scores or rate of a mystical experience. Persisting Effects Questionnaire positive composite scores 30 days after completion of the last dose were significantly higher than negative composite scores. Persisting Effects Questionnaire results revealed a moderate increase in sense of well-being or life satisfaction on average that was associated with the maximum Mystical Experience Questionnaire total score. Pharmacokinetic measures were associated with dose but not with Mystical Experience Questionnaire total scores or rate of a mystical experience.Conclusions: High doses of psilocybin elicited subjective effects at least as strong as the lower doses and resulted in positive persisting subjective effects 30 days after, indicating that a complete mystical experience was not a prerequisite for positive outcomes. [ABSTRACT FROM AUTHOR]- Published
- 2018
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5. The effect of bundling medication-assisted treatment for opioid addiction with mHealth: study protocol for a randomized clinical trial.
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Gustafson Sr, David H., Landucci, Gina, McTavish, Fiona, Kornfield, Rachel, Johnson, Roberta A., Mares, Marie-Louise, Westergaard, Ryan P., Quanbeck, Andrew, Alagoz, Esra, Pe-Romashko, Klaren, Thomas, Chantelle, and Shah, Dhavan
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DRUG abuse treatment ,OPIOID abuse ,MOBILE health ,SMARTPHONES ,HIV infection risk factors ,HEPATITIS C risk factors ,CLINICAL trials - Abstract
Background: Opioid dependence has devastating and increasingly widespread consequences and costs, and the most common outcome of treatment is early relapse. People who inject opioids are also at disproportionate risk for contracting the human immunodeficiency virus (HIV) and hepatitis C virus (HCV). This study tests an approach that has been shown to improve recovery rates: medication along with other supportive services (medication-assisted treatment, or MAT) against MAT combined with a smartphone innovation called A-CHESS (MAT + A-CHESS). Methods/design: This unblinded study will randomly assign 440 patients to receive MAT + A-CHESS or MAT alone. Eligible patients will meet criteria for having an opioid use disorder of at least moderate severity and will be taking methadone, injectable naltrexone, or buprenorphine. Patients with A-CHESS will have smartphones for 16 months; all patients will be followed for 24 months. The primary outcome is the difference between patients in the two arms in percentage of days using illicit opioids during the 24-month intervention. Secondary outcomes are differences between patients receiving MAT + A-CHESS versus MAT in other substance use, quality of life, retention in treatment, health service use, and, related to HIV and HCV, screening and testing rates, medication adherence, risk behaviors, and links to care. We will also examine mediators and moderators of the effects of MAT + A-CHESS. We will measure variables at baseline and months 4, 8, 12, 16, 20, and 24. At each point, patients will respond to a 20-to 30-min phone survey; urine screens will be collected at baseline and up to twice a month thereafter. We will use mixed-effects to evaluate the primary and secondary outcomes, with baseline scores functioning as covariates, treatment condition as a between-subject factor, and the outcomes reflecting scores for a given assessment at the six time points. Separate analyses will be conducted for each outcome. Discussion: A-CHESS has been shown to improve recovery for people with alcohol dependence. It offers an adaptive and extensive menu of services and can attend to patients nearly as constantly as addiction does. This suggests the possibility of increasing both the effectiveness of, and access to, treatment for opioid dependence. Trial registration: ClinicalTrials.gov, NCT02712034. Registered on 14 March 2016. [ABSTRACT FROM AUTHOR]
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- 2016
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6. Implementing an mHealth system for substance use disorders in primary care: a mixed methods study of clinicians' initial expectations and first year experiences.
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Mares, Marie-Louise, Gustafson, David H., Glass, Joseph E., Quanbeck, Andrew, McDowell, Helene, McTavish, Fiona, Atwood, Amy K., Marsch, Lisa A., Thomas, Chantelle, Shah, Dhavan, Brown, Randall, Isham, Andrew, Nealon, Mary Jane, and Ward, Victoria
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SUBSTANCE abuse treatment ,DRUG abuse ,SMARTPHONES ,CLINICAL trials ,MEDICAL research ,RANDOMIZED controlled trials - Abstract
Background: Millions of Americans need but don't receive treatment for substance use, and evidence suggests that addiction-focused interventions on smart phones could support their recovery. There is little research on implementation of addiction-related interventions in primary care, particularly in Federally Qualified Health Centers (FQHCs) that provide primary care to underserved populations. We used mixed methods to examine three FQHCs' implementation of Seva, a smart-phone app that offers patients online support/discussion, health-tracking, and tools for coping with cravings, and offers clinicians information about patients' health tracking and relapses. We examined (a) clinicians' initial perspectives about implementing Seva, and (b) the first year of implementation at Site 1. Methods: Prior to staggered implementation at three FQHCs (Midwest city in WI vs. rural town in MT vs. metropolitan NY), interviews, meetings, and focus groups were conducted with 53 clinicians to identify core themes of initial expectations about implementation. One year into implementation at Site 1, clinicians there were re-interviewed. Their reports were supplemented by quantitative data on clinician and patient use of Seva. Results: Clinicians anticipated that Seva could help patients and make behavioral health appointments more efficient, but they were skeptical that physicians would engage with Seva (given high caseloads), and they were uncertain whether patients would use Seva. They were concerned about legal obligations for monitoring patients' interactions online, including possible "cries for help" or inappropriate interactions. One year later at Site 1, behavioral health care providers, rather than physicians, had incorporated Seva into patient care, primarily by discussing it during appointments. Given workflow/load concerns, only a few key clinicians monitored health tracking/relapses and prompted outreach when needed; two researchers monitored the discussion board and alerted the clinic as needed. Clinician turnover/leave complicated this approach. Contrary to clinicians' initial concerns, patients showed sustained, mutually supportive use of Seva, with few instances of misuse. Conclusions: Results suggest the value of (a) focusing implementation on behavioral health care providers rather than physicians, (b) assigning a few individuals (not necessarily clinicians) to monitor health tracking, relapses, and the discussion board, (c) anticipating turnover/leave and having designated replacements. Patients showed sustained, positive use of Seva. [ABSTRACT FROM AUTHOR]
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- 2016
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7. Consulting Psychiatry within an Integrated Primary Care Model.
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Schreiter, Elizabeth A. Zeidler, Pandhi, Nancy, Fondow, Meghan D. M., Thomas, Chantelle, Vonk, Jantina, Reardon, Claudia L., and Serrano, Neftali
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COMMUNITY health services ,HEALTH services accessibility ,INTEGRATED health care delivery ,MEDICAL referrals ,MENTAL health services ,PRIMARY health care ,PSYCHIATRY ,MEDICALLY underserved persons - Abstract
After implementation of an integrated consulting psychiatry model and psychology services within primary care at a federally qualified health center, patients have increased access to needed mental health services, and primary care clinicians receive the support and collaboration needed to meet the psychiatric needs of the population. [ABSTRACT FROM AUTHOR]
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- 2013
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8. Initial examination of characteristics of patients who are high utilizers of an established primary care behavioral health consultation service.
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Fondow, Meghan, Zeidler Schreiter, Elizabeth, Thomas, Chantelle, Grosshans, Ashley, Serrano, Neftali, and Kushner, Kenneth
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MENTAL health consultation , *MENTAL health services use , *MENTAL health services , *INTEGRATED health care delivery , *PRIMARY care , *HEALTH promotion , *MEDICAL care , *MEDICAL referrals , *PATIENTS , *PRIMARY health care - Abstract
Obective: Although much has been studied regarding high-utilizing patients of medical services, no studies have been published regarding high-utilizing patients of integrated primary care behavioral health (PCBH) services. The primary purpose of the current study was to examine characteristics of high-utilizing patients of PCBH services and model adherence. The secondary purpose was to describe the process of conducting this research by clinicians in integrated care.
Method: Data were obtained from electronic health records retrospectively for the study's time period, 2007-2013, for the sample of all patients who met with the behavioral health consultation team during that time. Variables include demographics, diagnoses, involvement in additional services, and scores on a patient-complexity scale for a subset of patients. Chi-square analyses, t tests and logistic regression analyses were performed.Results: The results demonstrate significant associations between key demographic characteristics, use of population-based augmentation services (i.e., consulting psychiatry, care management, substance-abuse consulting), and high-utilizing status. Model adherence was maintained over time. Logistic regression analysis, controlling for high-utilizing status and number of visits, demonstrated a significant relationship between more complex diagnostic categories and behavioral health issues.Discussion: There are differences between high-utilizing patients and nonhigh-utilizing patients suggestive of increased clinical severity and appropriate use of services while maintaining PCBH model integrity. The use of the population-based augmentation services is associated with high-utilizer status, and reflects the ability of these services to target those patients who most need the clinical care. (PsycINFO Database Record [ABSTRACT FROM AUTHOR]- Published
- 2017
- Full Text
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