9 results on '"Uddin, Mohi"'
Search Results
2. Health-Related Quality of Life among Medical Students and Its Associated Factors: A Cross-Sectional Study.
- Author
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Uddin, Mohi, Naeem, Nimra, Khalid, Zainab, Saleem, Aqsa, Tariq, Memona, and Sana, Laiba
- Subjects
PHYSICAL mobility ,QUALITY of life ,MEDICAL students ,SOCIAL skills ,DENTAL schools - Abstract
Objective: To assess the health-related quality of life (HRQOL) and its associated factors among medical students residing in Faisalabad, Pakistan. Methods: This cross-sectional study was conducted at Aziz Fatimah Medical and Dental College, Faisalabad, Pakistan from July 2023 to December 2023. All medical students aged 18 years and above were included. HRQOL was assessed using the 36-Item Short Form Survey (SF-36), covering eight domains: Physical Functioning, Role Limitations due to Physical Health, Role Limitations due to Emotional Problems, Vitality, Mental Health, Social Functioning, Bodily Pain, and General Health Perception. Each domain was scored from 0 (low) to 100 (high). Physical and Mental Component Summary scores were also calculated. Results: Of total 300 students, SF-36 domains showed higher mean scores in Bodily Pain and Physical Functioning i.e., 66.6 ±24.9 and 61.6 ±29.1. Males reported significantly higher mean scores in General Health Perception (pvalue < 0.001) and Vitality (p-value 0.013), while females had significantly higher Physical Functioning scores (pvalue <0.005). Students >21 years had significantly higher mean scores in Physical Functioning (p-value 0.017). Furthermore, day scholars showed significantly better mean scores in Physical Functioning (p-value <0.001), Bodily Pain (p-value 0.020), Social Functioning (p-value 0.030), and Physical Component Summary (p-value <0.001) than hostelites. Students who exercised (p-value 0.020), had strong family relationships (p-value 0.003), and faced no distressing family events (p-value <0.001) reported significantly higher SF-36 scores. Conclusion: Overall, SF-36 domains showed higher mean scores in Bodily Pain and Physical Functioning, with significant differences in HRQOL based on age, gender, residence, and lifestyle factors among medical students. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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3. Effect of transforming growth factor-β1 on functional expression of monocarboxylate transporter 1 in alveolar epithelial A549 cells
- Author
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Uddin, Mohi, Kawami, Masashi, Yumoto, Ryoko, and Takano, Mikihisa
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- 2020
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4. Evaluation of Antioxidant, Cytotoxic and Hepato-protective Effect of Bridelia tomentosa Fruit Extract.
- Author
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Rahman, Mohammad A., Hasan, Nazmul A. H. M., Mondal, Milon, Uddin, Mohi, Wahed, Tania B., and Alam, Khairul K. M.
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PHYLLANTHACEAE ,HERBAL medicine ,ANTIOXIDANTS ,ACETAMINOPHEN ,CELL-mediated cytotoxicity - Abstract
Over the past decade, plant derived herbal medicines have become a worldwide concern. This study explored the anti-oxidant, cytotoxic and hepatoprotective potential of the fruit of Bridelia tomentosa. The ethanolic extract of Bridelia tomentosa fruits was evaluated for in-vitro antioxidant, cytotoxic and hepato-protective properties in Sprague-Dawley male rats. Total phenol, flavonoid and antioxidant capacity of the plant extract were extimated as 99.04145 ± 1.195mg/g GAE, 126.5046 ± 3.095mg/g QE and 372.094 ± 3.148 mg/g AAE. The extract showed good inhibitory potential of DPPH free radical (IC50 = 30.579 ± 1.895 µg/ml) and exhibited poor cytotoxic potential (LC50 = 537.693 ± 70.099 µg/ml). The fruit extract of Bridelia tomentosa was found safe at 6000mg/kg BW dose in rats. Bridelia tomentosa fruit extract was administered at two different doses (250mg/kg-body weight and 500mg/kg-body weight) in Sprague-Dawley male rats and improved all the hepatic parameters in paracetamol induced hepatic injury and highest effect was observed at 500mg/kg BW dose. At 500mg/kg BW dose, the fruit extract, reduced the ALT, AST and ALP level to 38.250 ± 1.652, 25.500 ± 2.754 and 139.250 ± 10.515 µ/L (p< 0.05) respectively. The fruit extract also moderately decreased total bilirubin level. The fruit extract was able to reverse the effect of hepatic damage caused by paracetamol significantly as evidenced from histopathological examination. Fruits of Bridelia tomentosa could be a good source of newer antioxidant and hepato-protective agents and isolation of potent bioactive compounds are highly suggested. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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5. Retinal Ganglion Cell Topography and Spatial Resolving Power of Eye in the Native Chicken of Bangladesh.
- Author
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Uddin, Mohi, Faruq, Abdullah Al, Hasan Sohel, Md Shahriar, Imamoto, Yasushi, and Rahman, Mohammad Lutfur
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RETINAL ganglion cells , *OPTIC disc , *CHICKENS , *RETINA , *MICROSCOPY , *CELL size - Abstract
The distribution of retinal ganglion cells (RGCs) was observed in the retinal wholemount of native chicken (Gallus gallus domestricus) of Bangladesh by using light microscopy. We considered five different anatomic regions (central, nasal, temporal, dorsal, and ventral) of Nissl stained wholemount, and the RGCs were counted, plotted, and measured accordingly. The average area of the retina was 431.75 mm2 while the total number of ganglion cells was 2124431 on average. Only the central area of the retina was the peak density (10400 cells/mm2 ) area, signifying the acute visual area, whilst the maximum spatial resolving power was 11 cycles/degree. The overall concentration of RGCs gradually declined towards the periphery but the size of cells generally decreased towards centrally. The size of ganglion cell was not uniform (12 to 180 µm2 ), specifically the central retina, just above the optic disc was packed with tiny-sized cells. The number, topographic distribution, and size of RGCs in native chicken signified their domesticated or terrestrial characters, uneven visual acuteness, and possibly only the central retina was the area for fine vision as the function of RGCs. [ABSTRACT FROM AUTHOR]
- Published
- 2022
6. Distribution of neuronal structures immunoreactive for parvalbumin in the midcingulate cortex of the rabbit.
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Uddin, Mohi and Shibata, Hideshi
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CALCIUM-binding proteins , *RABBITS , *CINGULATE cortex - Abstract
The rabbit midcingulate cortex that enclosed four cortical areas was immunohistochemically studied using a calcium‐binding protein, parvalbumin, as a neurochemical marker. The distribution of parvalbumin‐immunopositive somata and fibres was similar across all four areas, where they were present mainly in layers 2/3 and 5. However, there were a slightly greater number of the immunopositive structures in the two ventral areas than the two dorsal areas. Similarity in the distribution of parvalbumin‐immunopositive structures across the four areas suggests that neurons expressing parvalbumin may be involved in similar functions across the constituent areas of the rabbit midcingulate cortex. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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7. Ethnopharmacological investigation of the aerial part of Phragmites karka (Poaceae).
- Author
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Sultan, Ramiz Ahmed, Hafez Kabir, Mohammad Shah, Nasir Uddin, Mir Muhammad, Uddin, Mohi, Mahmud, Zobaer Al, Raihan, Sheikh Zahir, and Qais, Nazmul
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ANTIDIARRHEALS ,ANALGESICS ,ANTI-inflammatory agents ,BIOLOGICAL models ,DRUG design ,CLINICAL drug trials ,GLUCOSE tolerance tests ,HYPOGLYCEMIC agents ,METHANOL ,MICE ,ORGANIC compounds ,PLANT extracts - Abstract
Background: In this ethnopharmacological study, methanolic extract of the aerial plant parts of Phragmites karka (Family: Poaceae) and its petroleum ether and carbon tetrachloride fractions were investigated for bioactivities in Swiss-albino mice, namely, analgesic, central nervous system (CNS) depressant, hypoglycemic, and antidiarrheal activity. Methods: The cold methanolic extract of the aerial plant parts of Phragmites karka (MEPK) was first prepared, and it was then further fractionated as petroleum ether (PEFMEPK) and carbon tetrachloride (CTFMEPK) fractions. Analgesic activity was performed employing acidic acid-induced writhing test, central analgesic effect by radiant heat tail-flick method. CNS depressant activity was evaluated by phenobarbitone-induced sleeping time test. Hypoglycemic activity was tested by glucose tolerance test (GTT). Antidiarrheal activity was evaluated by castor oil-induced diarrhea method. For all in vivo tests, doses of 200 and 400 mg/kg body weight were used. Results: In the mice model, the MEPK, PEFMEPK, and CTFMEPK fractions showed significant peripheral analgesic activity at a dose of 400 mg/kg body weight with percentage of inhibition of acetic acid-induced writhing 77.67 (p< 0.001), 33.50 (p< 0.001), and 40.29 (p< 0.001), respectively, compared to the standard dichlofenac (60.68%, p < 0.001) group. The hypoglycemic properties of MEPK, PEFMEPK, and CTFMEPK extracts were evaluated in normoglycemic mice where the reduction of blood glucose level after 30 min of glucose load were 69.85%, 78.91%, and 72.73%, respectively, and for standard glibenclamide, the reduction was 72.85%. All results were significant (p < 0.05). In the case of the CNS depressant activity by phenobarbitone-induced sleeping time test, the crude ME significantly reduced sleep latency by 57.14% and increased the duration of sleep by 63.29% compared to the control, which were comparable to that of standard diazepam (65.71% and 77.62%, respectively). Among all the extract and fractions, methanolic extract showed the maximum antidiarrheal effect. The methanolic extract at 200 mg/kg dose induced a significant decrease in the total number of defecation in 4 h (69.05% of inhibition, p < 0.001) and at 400 mg/kg dose showed 76.19% of inhibition (p< 0.001). Conclusions: In light of the available literature, these findings represent the first experimental investigation of biological activities of P. karka in the perspective of their traditional use. [ABSTRACT FROM AUTHOR]
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- 2017
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8. Macroanatomy of the Bones of Pelvis and Hind Limb of an Asian Elephant (Elephas maximus).
- Author
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Shil, Subrata Kumar, Quasem, Md. Abul, Rahman, Mohammad Lutfur, Kibria, A. S. M. Golam, Uddin, Mohi, and Ahasan, A. S. M. Lutful
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PELVIC bones , *HINDLIMB , *ANATOMY education , *BUTTOCKS , *ASIATIC elephant , *ANATOMY , *PHYSIOLOGY - Abstract
Recent excavated skeleton of an adult female Asian Elephant (Elephas maximus), died in dystokia in Bangladesh was used for macro anatomical study. Some unique morphological features of bones of hind limb were observed. Pelvic canal was more oval and the wings of ilium were wider. Rump slope was about 36°. Angle between femur and tibia was close to 180°. In Femur, the major trochanter was located at the lower level of head. Minor trochanter, fovea capitis and trochanteric ridge were absent. Supracondyloid fossa was shallow but the intercondyloid fossa was deep. Posterior surface of patella possessed a blunt vertical ridge. The articular surfaces of both tibial condyles were clearly concave. The tibia and the fibula were articulated proximally and distally with keeping a wide interosseous space. Instead of tibial tuberosity, there was an elongated triangular depression in proximal part. There were six tarsal bones arranged in three rows. The comparative size of the distal tarsal bones were III+IV > I > II. The comparative lengths of the metatarsal bones were III > II > IV > V> I. Digits I and V were the most vertical and digit III was the most horizontal. The proximal phalanx [ABSTRACT FROM AUTHOR]
- Published
- 2013
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9. Distribution of calretinin immunopositive somata and fibers in the rabbit midcingulate cortex.
- Author
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Uddin M and Shibata H
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- Animals, Female, Immunohistochemistry, Neural Inhibition, Calbindin 2 metabolism, Gyrus Cinguli anatomy & histology, Neurons metabolism, Rabbits anatomy & histology
- Abstract
The midcingulate cortex (MCC; area 24') resides in the mid-rostrocaudal part of the cingulate gyrus, and it plays important roles in nociceptive, cognitive and skeletomotor functions. The MCC has recently been shown to consist of four cortical areas (areas a24a', a24b', p24a' and p24b') in the rabbit, based on immunohistochemistry. To further characterize the organization of these areas, here we immunohistochemically identified structures immunopositive (+) for calretinin (CR) as a marker of a subpopulation of inhibitory neurons. CR+ somata were identified as multipolar and bipolar neurons. The multipolar neurons were predominant throughout the MCC. CR+ somata were present mainly in layer (L) 2/3 and L6, and CR+ fibers occurred mainly in L1, L2/3 and L6. However, there were differences in the distribution of CR+ structures in each area. CR+ somata tended to be most densely distributed in area a24a', followed by area p24a', area a24b' and area p24b'. CR+ fibers were most densely distributed in area p24a', followed by area p24b', area a24a' and area a24b'. In addition, only areas p24a' and p24b' enclosed patchy CR+ fibers and terminals in deep L2/3. These results show the distinct distribution of CR+ structures in each area of the MCC in the rabbit, suggesting that CR+ neurons may contribute to information processing for cognitive functions in somewhat different manners in each area of the MCC.
- Published
- 2019
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