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Your search keyword '"Werner, C. L"' showing total 7 results
Start Over Author "Werner, C. L" Publication Type Academic Journals
7 results on '"Werner, C. L"'

6. Case management for children and families.

Author

Horst L, Werner RR, and Werner CL

Subjects
Adult, Child, Clinical Competence standards, Humans, Total Quality Management organization & administration, Case Management organization & administration, Child Health Services organization & administration, Family Health, Models, Organizational, Patient-Centered Care organization & administration
Published
2000

7. Clinical efficacy of the Abbott Tacrolimus II assay for the IMx.

Author

Cannon RD, Wong SH, Hariharan S, Adams MB, Johnson CP, Roza AM, Pearson ML, and Werner CL

Subjects
Adult, Black or African American, Drug Monitoring, Female, Graft Rejection blood, Humans, Male, Middle Aged, Reagent Kits, Diagnostic, Sensitivity and Specificity, White People, Graft Rejection prevention & control, Immunosuppressive Agents blood, Tacrolimus blood
Abstract

Monitoring tacrolimus is essential to maintain therapeutic concentrations. Performance of the new Abbott Tacrolimus assay (FK II) was evaluated and compared to the original tacrolimus assay (FK I). 189 trough whole blood samples from transplant cases were included in the study. Samples (n = 117) with FK I concentrations > 5 ng/mL were reanalyzed with the FK II assay. Patient samples (n = 43) that had FK I concentration < 5 ng/mL with apparent mean and range of 3.1 ng/mL and 0.7 to 4.5 ng/mL, respectively, were also reanalyzed with FK II to yield a mean of 5.9 ng/mL with a range of 2.9 to 10.8 ng/mL. Checking for patient compliance, samples (n = 10) with a FK I concentration of 0 ng/mL were re-analyzed. With one exception of a mislabeled cyclosporine sample, all samples (n = 9) showed FK506 levels greater than 2 ng/mL with the FK II assay. The FK II assay was shown to be a clinically efficacious assay, with improved sensitivity and acceptable precision versus the previous FK I assay.

Published
1999

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